Protein
- UniProt accession
- Q9XJP3 [UniProt]
- Protein name
- Tail spike protein
- RBP type
-
TSPTSPTSP
- Protein sequence
-
MTDIITNVVIGMPSQLFTMARSFKAVANGKIYIGKIDTDPVNPENQIQVYVENEDGSHVPASQPIVINAAGYPVYNGQIVKFVTEQGHSMAVYDAYGSQQFYFQNVLKYDPDQFGPDLIEQLAQSGKYSQDNTKGDAMIGVKQPLPKAVLRTQHDKNKEAISILDFGVIDDGVTDNYQAIQNAIDAVASLPSGGELFIPASNQAVGYIVGSTLLIPGGVNIRGVGKASQLRAKSGLTGSVLRLSYDSDTIGRYLRNIRVTGNNTCNGIDTNITAEDSVIRQVYGWVFDNVMVNEVETAYLMQGLWHSKFIACQAGTCRVGLHFLGQCVSVSVSSCHFSRGNYSADESFGIRIQPQTYAWSSEAVRSEAIILDSETMCIGFKNAVYVHDCLDLHMEQLDLDYCGSTGVVIENVNGGFSFSNSWIAADADGTEQFTGIYFRTPTSTQSHKIVSGVHINTANKNTAANNQSIAIEQSAIFVFVSGCTLTGDEWAVNIVDINECVSFDKCIFNKPLRYLRSGGVSVTDCYLAGITEVQKPEGRYNTYRGCSGVPSVNGIINVPVAVGATSGSAAIPNPGNLTYRVRSLFGDPASSGDKVSVSGVTINVTRPSPVGVALPSMVEYLAI
- Physico‐chemical
properties -
protein length: 623 AA molecular weight: 67065,69120 Da isoelectric point: 5,09513 aromaticity: 0,08668 hydropathy: -0,03435
Domains
Domains [InterPro]
Legend:
Pfam
SMART
CDD
TIGRFAM
HAMAP
SUPFAM
PRINTS
Gene3D
PANTHER
Other
Taxonomy
| Name | Taxonomy ID | Lineage | |
|---|---|---|---|
| Phage |
Shigella phage Sf6 [NCBI] |
2905959 | Viruses > Duplodnaviria > Heunggongvirae > Uroviricota > Caudoviricetes |
| Host | No host information | ||
Coding sequence (CDS)
Coding sequence (CDS)
No CDS data available.
Gene Ontology
| Description | Category | Evidence (source) | |
|---|---|---|---|
| GO:0098024 | virus tail, fiber | Cellular Component | IDA:UniProtKB (UniProt) |
| GO:0052775 | endo-1,3-alpha-L-rhamnosidase activity | Molecular Function | IDA:UniProtKB (UniProt) |
| GO:0044409 | symbiont entry into host | Biological Process | IDA:UniProtKB (UniProt) |
| GO:0098994 | symbiont entry into host cell via disruption of host cell envelope | Biological Process | IEA:UniProtKB-KW (UniProt) |
| GO:0098995 | symbiont entry into host cell via disruption of host cell envelope lipopolysaccharide | Biological Process | IEA:UniProtKB-KW (UniProt) |
| GO:0019062 | virion attachment to host cell | Biological Process | IDA:UniProtKB (UniProt) |
Enzymatic activity
No enzymatic activity data available.
Tertiary structure
PDB ID
2VBE
PDB ID
2VBK
PDB ID
2VBM
PDB ID
4URR
PDB ID
7SG7
PDB ID
7UKJ
PDB ID
e65d0a8b910307962c0c4b66affe666068c94983828182a52e9b45343130689c
Literature
| Title | Authors | Date | PMID | Source |
|---|---|---|---|---|
| Enzymic and molecular properties of base-plate parts of bacteriophage P22. | Iwashita S, Kanegasaki S | 1976-05-17 | 6284 | PubMed |
| The tailspike protein of Shigella phage Sf6. A structural homolog of Salmonella phage P22 tailspike protein without sequence similarity in the beta-helix domain. | Freiberg A, Morona R, Van den Bosch L, Jung C, Behlke J, Carlin N, Seckler R, Baxa U | 2003-01-17 | 12424253 | PubMed |
| An intersubunit active site between supercoiled parallel beta helices in the trimeric tailspike endorhamnosidase of Shigella flexneri Phage Sf6. | Müller JJ, Barbirz S, Heinle K, Freiberg A, Seckler R, Heinemann U | 2008-05 | 18462681 | PubMed |
| Enzymic and Molecular Properties of Base-Plate Parts of Bacteriophage P22 | Shintaro IWASHITA, Shiro KANEGASAKI | 1976-05 | 10.1111/j.1432-1033.1976.tb10392.x | DOI |
| The Shigella flexneri bacteriophage Sf6 tailspike protein (TSP)/endorhamnosidase is related to the bacteriophage P22 TSP and has a motif common to exo- and endoglycanases, and C-5 epimerases | James E. H. Chua, Paul A. Manning, Renato Morona | 1999-07-01 | 10.1099/13500872-145-7-1649 | DOI |
| The Tailspike Protein of Shigella Phage Sf6 | Alexander Freiberg, Renato Morona, Luisa Van Den Bosch, Christiane Jung, Joachim Behlke, Nils Carlin, Robert Seckler, Ulrich Baxa | 2003-01 | 10.1074/jbc.m205294200 | DOI |
| An Intersubunit Active Site between Supercoiled Parallel β Helices in the Trimeric Tailspike Endorhamnosidase of Shigella flexneri Phage Sf6 | Jürgen J. Müller, Stefanie Barbirz, Karolin Heinle, Alexander Freiberg, Robert Seckler, Udo Heinemann | 2008-05 | 10.1016/j.str.2008.01.019 | DOI |