Protein

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UniProt accession
A0A219YHC2 [UniProt]
Protein name
Depolymerase 2, capsule K5-specific
RBP type
TF
Evidence Phold
Probability 1,00
TSP
Evidence DepoScope
Probability 1,00
TSP
Evidence RBPdetect
Probability 0,91
TSP
Evidence RBPdetect2
Probability 0,95
Protein sequence
MIKNDFNQPKGSTIGVLKDGRTIQEAFDSLGYLGVAVLSPANYGAKGDGKADDTIPLRQCVQDACALGGRVVGTVGAEYKISGTIAGTVGDGKYVELDFTGSKFVPTTDDAVMTITGVATSPVAEVTVEVVSVNLGNGSTNTIAMKVTAPGGHSFTKKGEIGKAWSPVLCLNNDLSTQYAGEPFVVGLVESSTVFYTTSVFTELYMGTSLKVIRVPTTQVVVKGLDVESEWTTGWKASTLTLSGLLRPFVYKPKCKNINGPFVNLTGCYGATVFLPEGDNLRNAPSEGAYGYFVNDSASFGSTIYGINCTNARHAYTTSSPRSEPTDDKWWLKGRTLFSEITNGLGTGCHNAFDTHSPSYGIKFTNCRAVGDFRGVDTGGAGFQIRGDRSSLVDCTAINSKIGAAFTAVNISGNSELYISGFTYEGPAGHLALSLSGKAGQVNRVTISDSRWKTLEQYATAITNVEVSASNVEAVVDSATTASAAWRIGEGATLRTRGGAARFSAGSGHSVISLAASGAKVDVGDLEVTGSSFMQYLLATLSQYAGDVYIEADLDGAIPGNPVGGGGTDLKAAVVYTAGNKFRRPLAYRALTIGNANGNTLGLNYSGHDVITWEITATVAGANVNGITPGAFIGQQLNIGSSPASTQQLIINNGTNIAMGHAVTLEAGRGVTLYWNGANWRSGSV
Physico‐chemical
properties
protein length:685 AA
molecular weight: 71411,08310 Da
isoelectric point:5,97721
aromaticity:0,08467
hydropathy:-0,02628

Domains

Domains [InterPro]
DC_1231
ATT
1–204
DC_1231 IPR057996
IPR012334
STR
33–488
IPR012334
DC_1484
STR
185–673
DC_1484
A0A219YHC2
1 685
Architecture
ATT
STR
ATT 1-204 | STR 205-681 |
Legend: ATT STR RBD CBM LEC ENZ CHP LNK TAS TTP UNK Unmapped

Tail Spike Domain Segmentation

Tail Spike Domain Segmentation

This protein has been segmented into three structural domains: N-terminal, central domain, and C-terminal.

Domain Layout
N-terminal
Central
C-terminal
A0A219YHC2
1 685
Domain Start End Length (AA) Confidence
N-terminal 1 52 52 0,9487
Central domain 53 587 536 0,9788
C-terminal 588 685 97 0,9900
Legend: N-terminal Central domain C-terminal
3D Structure with Domain Coloring

The structure is colored according to the domain segmentation: N-terminal (blue), Central (green), C-terminal (pink).

Domain Coloring
N-terminal
1-52
Central
53-587
C-terminal
588-685

Taxonomy

  Name Taxonomy ID Lineage
Phage Klebsiella phage K5-2
[NCBI] 		1932361 Viruses > Duplodnaviria > Heunggongvirae > Uroviricota > Caudoviricetes
Host Klebsiella pneumoniae subsp. ozaenae
[NCBI] 		574 Pseudomonadota > Gammaproteobacteria > Enterobacterales > Enterobacteriaceae > Klebsiella > Klebsiella pneumoniae

Coding sequence (CDS)

Coding sequence (CDS)

No CDS data available.

Genome Context

Genome Context

Gene Ontology

Description Category Evidence (source)
GO:0098015 virus tail Cellular Component IEA:UniProtKB-KW (UniProt)
GO:0098671 adhesion receptor-mediated virion attachment to host cell Biological Process IEA:UniProtKB-KW (UniProt)
GO:0098994 symbiont entry into host cell via disruption of host cell envelope Biological Process IEA:UniProtKB-KW (UniProt)
GO:0098996 symbiont entry into host cell via disruption of host cell glycocalyx Biological Process IDA:UniProtKB (UniProt)

Tertiary structure

PDB ID
bf314cfde594426fa6f6041149057bb512202d15b1c1a0f020a7504893ff53fc
ESMFold
Source ESMFold
Method ESMFold
Resolution 0,7844
Oligomeric State monomer
Download PDB
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50