Protein

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Genbank accession
QBX30214.1 [GenBank]
Protein name
hyaluronate lyase
RBP type
TSP
Evidence DepoScope
Probability 1,00
TSP
Evidence RBPdetect2
Probability 0,96
Protein sequence
MTETIPLRVQFKRMTAEEWTRSDVILLESEIGFETDTGYAKFGDGKNQFSKLKYLNKPDLGAFAQKEETNSKITKLESSKADKNAVYLKAESKIELDKKLNLKGGVMTGQLQFKPNKSGIKPSSSVGGAINIDMSKSEGAGVVVYSNNDTSDGPLMSLRTGKETFNQSALFVDYSGKTNAVNIAMRQPTTPNFSSALNITSGNENGSAMQIRGVEKALGTLKITHENPNVEANYDENAAALSIDIVKKQKGGKGTAAQGIYINSTSGTTGKLLRIRNLGDDKFYVKHDGGFYAKKTSQIDGNLKLKNPTADDHAATKAYVDSEVKKLKALLMDKQV
Physico‐chemical
properties
protein length:336 AA
molecular weight: 36483,84200 Da
isoelectric point:9,27934
aromaticity:0,06548
hydropathy:-0,57708

Domains

Domains [InterPro]
SSF69349
STR
7–332
SSF69349
IPR041352
ATT
9–46
IPR041352 IPR009860
QBX30214.1
1 336
Architecture
ATT
STR
ATT 7-46 | STR 47-332 |
Legend: ATT STR RBD CBM LEC ENZ CHP LNK TAS TTP UNK Unmapped

Tail Spike Domain Segmentation

Tail Spike Domain Segmentation

This protein has been segmented into three structural domains: N-terminal, central domain, and C-terminal.

Domain Layout
N-terminal
Central
C-terminal
QBX30214.1
1 336
Domain Start End Length (AA) Confidence
N-terminal 1 108 108 0,9888
Central domain 109 307 200 0,0986
C-terminal 308 336 28 0,9875
Legend: N-terminal Central domain C-terminal
3D Structure with Domain Coloring

The structure is colored according to the domain segmentation: N-terminal (blue), Central (green), C-terminal (pink).

Domain Coloring
N-terminal
1-108
Central
109-307
C-terminal
308-336

Taxonomy

  Name Taxonomy ID Lineage
Phage Streptococcus phage Javan526
[NCBI] 		2548239 Viruses > Duplodnaviria > Heunggongvirae > Uroviricota > Caudoviricetes
Host Streptococcus pyogenes MGAS9429
[NCBI] 		370551 Bacillota > Bacilli > Lactobacillales > Streptococcaceae > Streptococcus > Streptococcus pyogenes

Coding sequence (CDS)

Coding sequence (CDS)
Genbank protein accession
QBX30214.1 [NCBI]
Genbank nucleotide accession
MK448975 [NCBI]
CDS location
range 33652 -> 34662
strand +
CDS
ATGACAGAAACTATACCGCTACGAGTCCAATTTAAGCGGATGACTGCCGAAGAATGGACTCGCAGCGATGTCATCTTACTTGAGAGTGAAATAGGCTTTGAGACCGATACAGGATATGCTAAGTTTGGTGATGGTAAAAACCAATTTAGTAAGCTTAAGTACCTTAATAAACCAGATCTAGGTGCGTTTGCACAAAAAGAAGAAACTAATAGTAAAATCACCAAATTAGAATCAAGCAAAGCAGATAAAAACGCTGTTTACTTAAAAGCAGAGTCAAAAATAGAGCTTGACAAGAAATTAAATCTCAAAGGCGGCGTCATGACAGGTCAACTACAGTTTAAACCTAATAAAAGTGGTATTAAACCCTCATCTTCCGTAGGAGGAGCGATTAACATTGATATGTCTAAATCGGAAGGTGCTGGTGTTGTTGTCTATTCTAACAATGATACCAGTGATGGGCCGTTAATGAGCTTGCGGACGGGTAAAGAGACCTTCAATCAATCAGCGCTTTTTGTCGATTACAGCGGTAAGACTAATGCCGTTAATATTGCGATGCGTCAGCCAACCACCCCCAATTTTTCCTCTGCGCTTAATATTACTAGCGGCAATGAAAATGGTAGTGCGATGCAAATTAGAGGCGTCGAAAAAGCATTGGGAACGCTCAAAATCACACACGAAAACCCAAACGTTGAGGCAAATTACGATGAAAACGCTGCAGCGTTATCTATTGATATCGTTAAAAAACAGAAAGGCGGAAAAGGTACTGCTGCTCAAGGAATCTACATTAACTCAACCTCAGGAACGACAGGGAAGTTGCTTAGGATTAGAAATCTTGGTGATGATAAGTTCTACGTCAAGCATGACGGTGGTTTTTATGCCAAGAAAACTTCGCAGATTGATGGCAACCTGAAACTCAAGAATCCCACAGCGGATGATCATGCGGCAACTAAAGCTTATGTTGATAGTGAAGTCAAAAAATTAAAAGCACTCTTAATGGATAAGCAAGTGTAA

Genome Context

Genome Context

Tertiary structure

PDB ID
3be72d85384b00a307dc95f3b5f8dd7ae2a87673f91703af9fc6c019b2bbdb97
ESMFold
Source ESMFold
Method ESMFold
Resolution 0,7724
Oligomeric State monomer
Download PDB
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50

Literature

Title Authors Date PMID Source
Prophages and satellite prophages are widespread among Streptococcus species and may play a role in pneumococcal pathogenesis Rezaei Javan,R., Ramos-Sevillano,E., Akter,A., Brown,J. and Brueggemann,A.B. 2018-12-20 — GenBank