Protein

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UniProt accession
A0A8S5TZF1 [UniProt]
Protein name
Cytosine specific methyltransferase
RBP type
TSP
Evidence DepoScope
Probability 1,00
Protein sequence
MNKKPMTLGSLFDGSGGFPLGGLISGITPLWASEVEPFPIRVTSKRIPQMKHLGDISTINGAEIEPVDIITFGSPCQDMSVAGKRSGLDGERSCLFYEAIRIVKEMRCKTNGQYPRYIVWENVPGAFSSNAGEDFKAVLEAVASVKGDYAVPCPPKGKWTGAGEILGDDFSIAWRCVDAQFWGVPQRRRRIYLVADFNGGCAGKILFESEGLFGNLEPSRCPWKRTAGTSEESTPATGIVLNDQGGSRMDVTEEFTCPLRAEAHHPPCVMESAGFCTEHSADSRGIGYEAEKSPTLRAGVVPATVYENHSQDTRYVGPLDVAQTVAATYGTGGNNQPFVVECPKTLKIRSGCEGGGKGALIQDNLSATLCCNNDQTLFIPKAYGICSKDSNAMKSPNPNSGFYKADTSRTLDGNGGNPTCNQGGIAIVEGNGSRPSHHGNGYAESDVMYTLNTVDRHAVVYAIDRESYNCGQNFARNMGISDEGVNSTLKATGPDAVAVPTYSSSKASFFISAEEELANTLVATDYKDPPLVNDTDGDLEYIVRRLTPTECARLQGFPDWWCADLGVKLPSEEELTRWAEIFETHRKIVGTSSKPKTRKQIFKWLQNPHSDSAEYKMWGNGVALPNVVYVLTGIVYYTQNEGV
Physico‐chemical
properties
protein length:643 AA
molecular weight: 69721,49100 Da
isoelectric point:5,37466
aromaticity:0,08709
hydropathy:-0,36625

Domains

Domains [InterPro]
IPR029063
STR
1–212
IPR029063 G3DSA:3.90.120.30
IPR001525
ATT
6–195
IPR001525
IPR029063
STR
6–634
IPR029063
IPR001525
ATT
6–588
IPR001525
IPR001525
ATT
7–23
IPR001525 IPR050750
IPR018117
Unmapped
68–80
IPR018117 IPR001525 IPR001525
A0A8S5TZF1
1 643
Architecture
ATT
STR
ATT 1-588 | STR 589-634 |
Legend: ATT STR RBD CBM LEC ENZ CHP LNK TAS TTP UNK Unmapped

Tail Spike Domain Segmentation

Tail Spike Domain Segmentation

This protein has been segmented into three structural domains: N-terminal, central domain, and C-terminal.

Domain Layout
N-terminal
Central
C-terminal
A0A8S5TZF1
1 643
Domain Start End Length (AA) Confidence
N-terminal 1 231 231 0,0814
Central domain 232 454 224 0,7834
C-terminal 455 643 188 0,5885
Legend: N-terminal Central domain C-terminal
3D Structure with Domain Coloring

The structure is colored according to the domain segmentation: N-terminal (blue), Central (green), C-terminal (pink).

Domain Coloring
N-terminal
1-231
Central
232-454
C-terminal
455-643

Taxonomy

  Name Taxonomy ID Lineage
Phage Siphoviridae sp. ctkkB9
[NCBI] 		2825644 Uroviricota > Caudoviricetes >
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
Genbank protein accession
DAF87585.1 [NCBI]
Genbank nucleotide accession
BK015964 [NCBI]
CDS location
range 12489 -> 14420
strand -
CDS
ATGAATAAGAAACCTATGACCCTCGGCAGCCTCTTTGACGGCTCCGGGGGGTTTCCTTTGGGAGGCTTGATTTCTGGTATCACCCCTTTGTGGGCATCGGAGGTCGAGCCTTTTCCTATTCGTGTAACAAGCAAGCGGATTCCTCAAATGAAGCACCTCGGAGATATCTCCACCATAAACGGTGCAGAAATTGAACCCGTGGACATCATCACTTTCGGAAGTCCCTGCCAGGATATGAGCGTTGCGGGTAAACGCAGCGGTCTTGACGGTGAACGCTCCTGCCTGTTCTACGAAGCAATCCGAATCGTAAAAGAAATGAGGTGTAAAACCAATGGACAATATCCAAGATACATCGTGTGGGAAAATGTCCCCGGTGCCTTTTCCTCAAACGCAGGAGAAGATTTCAAGGCAGTCCTTGAGGCAGTCGCGTCCGTCAAAGGTGACTATGCTGTCCCTTGTCCTCCGAAAGGGAAGTGGACAGGAGCAGGAGAAATCCTGGGAGATGATTTCAGCATCGCATGGAGATGTGTTGACGCGCAGTTTTGGGGAGTTCCCCAGAGAAGAAGACGTATCTATCTTGTCGCAGATTTTAATGGCGGGTGTGCCGGAAAAATATTATTTGAGTCAGAAGGCCTGTTTGGGAATCTTGAACCGAGCCGATGCCCGTGGAAAAGAACTGCCGGAACTTCTGAAGAAAGCACTCCTGCGACAGGCATCGTCTTAAATGATCAGGGTGGCAGCCGTATGGATGTCACCGAAGAGTTCACCTGTCCCCTTCGCGCCGAGGCTCACCATCCGCCTTGCGTGATGGAATCCGCAGGCTTTTGCACGGAACATTCTGCCGACAGCCGTGGCATTGGATATGAGGCAGAAAAATCTCCTACACTCCGAGCCGGAGTTGTTCCCGCCACTGTGTATGAAAACCACTCCCAAGATACCCGTTATGTGGGACCTCTTGATGTAGCACAGACTGTGGCAGCTACCTACGGCACAGGTGGAAACAATCAGCCTTTCGTGGTTGAATGTCCGAAAACATTAAAGATCCGTAGTGGCTGTGAAGGTGGTGGCAAAGGTGCTTTAATTCAAGATAATTTGTCCGCTACCTTGTGTTGCAACAATGACCAGACATTATTTATACCCAAAGCTTATGGAATCTGTTCCAAGGACAGCAACGCTATGAAGTCACCAAACCCCAACAGCGGTTTTTATAAAGCAGATACCTCCCGAACACTTGATGGCAATGGTGGAAACCCAACATGTAACCAGGGCGGCATTGCCATTGTTGAGGGCAACGGTTCAAGACCTTCCCACCACGGAAACGGCTATGCAGAAAGTGATGTCATGTACACCTTAAATACCGTTGACCGCCACGCCGTTGTCTATGCTATCGACCGTGAAAGTTATAACTGTGGTCAGAACTTCGCAAGAAATATGGGCATCAGTGATGAGGGTGTCAATTCCACATTAAAAGCCACGGGACCCGATGCGGTTGCCGTTCCCACCTACTCGAGCAGTAAGGCATCGTTCTTTATTTCTGCGGAAGAGGAACTTGCCAACACTTTAGTAGCTACGGATTACAAAGACCCTCCGCTGGTCAATGACACCGATGGTGATCTGGAATACATTGTCCGCAGGCTGACCCCTACGGAATGTGCAAGGCTCCAGGGATTCCCCGATTGGTGGTGTGCTGACCTCGGTGTAAAACTTCCTTCTGAAGAGGAACTCACACGGTGGGCAGAAATCTTTGAAACACATCGTAAGATTGTGGGAACATCAAGCAAACCGAAGACACGGAAACAAATCTTCAAGTGGCTGCAGAACCCTCACTCCGACTCGGCTGAGTATAAAATGTGGGGCAACGGCGTGGCACTTCCGAATGTAGTTTATGTGCTGACGGGCATCGTGTACTATACACAAAATGAAGGGGTATAA

Genome Context

Genome Context

Gene Ontology

Description Category Evidence (source)
GO:0008168 methyltransferase activity Molecular Function IEA:UniProtKB-KW (UniProt)
GO:0032259 methylation Biological Process IEA:UniProtKB-KW (UniProt)
GO:0099018 symbiont-mediated evasion of host restriction-modification system Biological Process IEA:UniProtKB-KW (UniProt)
GO:0052170 symbiont-mediated suppression of host innate immune response Biological Process IEA:UniProtKB-KW (UniProt)

Tertiary structure

PDB ID
0652bc19499c9aaf7ac1c27428cac3d3baf51956fd291538db4c7d5b89cdba92
ColabFold
Source ColabFold
Method ColabFold
Resolution 0,6156
Oligomeric State monomer
Download PDB
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50