Protein

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UniProt accession
A0A8S5NFE7 [UniProt]
Protein name
DNA-directed DNA polymerase
RBP type
TSP
Evidence DepoScope
Probability 0,98
Protein sequence
MARPKKVKYLVGDFETTVYEGQKNTEVWASAIVEMFTEDVSILNSIDETWKYLVTLKSNLIVYYHNLKFDGNFWISFFLNKLNLKQAYTGDGVNSCEWKHDKEMYNNTFKYTISEMGQWYSIKVKINNKVIEFRDSLKLLPFSVKEIGKAFKTKHQKLDMEYKGFRYAGCEIKQDEKKYIANDVLVVKEALEIVFQEGHNRLTIGSCCLAEYKQIVGKDDWKRRFPDVTQLELDSEIYGKSNVDAYIRKSYRGGWCYLVKGKENKIYTNGTTADVNSLYPSMMHSMSGNRYPVGKPMFWSGNFIPDKALQSNTYFFIRIKTKFYLKSGKLPFIQIKGNMLYKGTESLHTSDVFDKATGKYYDKYIDIDGNTCDTRVELTLTMTDYFLILEHYELVDFEILDGCYFYSEVGIFDEYIDKYAMIKMNSKGARRTLAKLFLNNLYGKMASSTDSSFKLAYVKDDNSIGFINITAKDKEAGYIPVGSAITSYARNFTIRAAQANYHGVNKRGFIYADTDSIHCDLPPEQITGIKVHETDFCAWKLESCWDKAIFARQKTYIEHVTHEDLQKIEEPYNNIKCAGMPQRCKDLFELSMSGKAVYEDYKENTPVNRFLFNQVTHEPIVRTFDDFKIGLNVPCKLIPKRIEGGVLLVESTYQMR
Physico‐chemical
properties
protein length:656 AA
molecular weight: 76047,18770 Da
isoelectric point:8,27795
aromaticity:0,13567
hydropathy:-0,41814

Domains

Domains [InterPro]
IPR036397
ATT
3–202
IPR036397 IPR023211 G3DSA:4.10.80.30
IPR012337
Unmapped
9–196
IPR012337 IPR023211
IPR004868
STR
57–165
IPR004868 IPR004868
IPR043502
Unmapped
240–603
IPR043502
IPR006172
Unmapped
270–283
IPR006172 G3DSA:3.30.1770.10 G3DSA:1.10.287.690 G3DSA:4.10.80.20 IPR006172
IPR006172
Unmapped
431–443
IPR006172 IPR017964
A0A8S5NFE7
1 656
Architecture
ATT
STR
RBD
ATT 3-202 | STR 203-565 | RBD 621-656
Legend: ATT STR RBD CBM LEC ENZ CHP LNK TAS TTP UNK Unmapped

Tail Spike Domain Segmentation

Tail Spike Domain Segmentation

This protein has been segmented into three structural domains: N-terminal, central domain, and C-terminal.

Domain Layout
N-terminal
Central
C-terminal
A0A8S5NFE7
1 656
Domain Start End Length (AA) Confidence
N-terminal 1 158 158 0,1068
Central domain 159 357 200 0,0427
C-terminal 358 656 298 0,8918
Legend: N-terminal Central domain C-terminal
3D Structure with Domain Coloring

The structure is colored according to the domain segmentation: N-terminal (blue), Central (green), C-terminal (pink).

Domain Coloring
N-terminal
1-158
Central
159-357
C-terminal
358-656

Taxonomy

  Name Taxonomy ID Lineage
Phage Podoviridae sp. ct2nF21
[NCBI] 		2826537 Uroviricota > Caudoviricetes >
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
Genbank protein accession
DAD93557.1 [NCBI]
Genbank nucleotide accession
BK015162 [NCBI]
CDS location
range 3055 -> 5025
strand +
CDS
ATGGCAAGGCCTAAAAAAGTAAAGTATCTGGTTGGGGACTTTGAAACGACAGTCTATGAGGGCCAGAAAAATACAGAGGTTTGGGCATCTGCCATTGTAGAAATGTTCACAGAAGATGTTTCTATATTAAATTCAATAGATGAAACGTGGAAATATCTGGTCACTTTAAAATCAAACTTAATAGTGTATTATCACAATCTAAAATTTGACGGTAACTTTTGGATATCGTTTTTTCTGAATAAACTAAATCTTAAACAAGCATATACTGGCGATGGTGTTAACTCTTGTGAATGGAAACATGACAAAGAAATGTATAACAACACGTTCAAGTACACTATTTCTGAAATGGGGCAATGGTACAGCATCAAAGTCAAGATAAATAATAAGGTTATAGAATTTCGTGATTCACTGAAGCTACTGCCATTTTCTGTCAAAGAAATAGGAAAAGCTTTTAAGACCAAGCATCAGAAGCTCGACATGGAATATAAAGGTTTTCGTTATGCAGGTTGTGAGATTAAACAAGATGAAAAAAAGTACATCGCTAACGATGTACTTGTTGTTAAAGAAGCCCTAGAGATTGTTTTTCAAGAGGGACATAATAGACTAACGATAGGTAGTTGTTGTCTAGCTGAATATAAACAAATAGTTGGTAAAGATGATTGGAAAAGAAGATTTCCAGACGTTACACAATTAGAACTAGATTCTGAGATATACGGAAAGTCAAACGTTGATGCCTATATAAGAAAGTCGTATAGGGGTGGTTGGTGTTATCTTGTAAAAGGAAAAGAAAACAAGATATATACTAACGGAACTACTGCTGATGTAAATTCTTTGTACCCATCTATGATGCACTCAATGTCTGGTAATAGATATCCTGTCGGAAAGCCGATGTTCTGGTCTGGTAACTTTATTCCAGACAAGGCTCTACAAAGCAACACGTATTTTTTCATCAGAATAAAAACAAAATTTTATTTGAAAAGTGGTAAGTTGCCATTCATTCAGATAAAAGGAAATATGTTATACAAGGGAACAGAGTCCTTACATACGTCTGATGTGTTCGACAAAGCTACTGGTAAGTATTACGATAAATACATAGATATTGATGGTAATACTTGTGATACAAGAGTAGAACTTACATTAACCATGACTGATTACTTTCTTATTCTTGAGCATTATGAGCTTGTTGACTTTGAGATTCTTGACGGTTGTTACTTTTATTCAGAAGTTGGAATATTTGATGAATACATTGATAAATACGCAATGATAAAGATGAACAGTAAAGGAGCTAGACGTACACTTGCGAAGCTTTTTTTAAACAATCTATATGGTAAGATGGCTTCATCTACTGACTCATCATTTAAGTTAGCATATGTTAAAGACGATAATTCAATAGGCTTCATAAACATAACAGCCAAGGATAAAGAAGCAGGTTATATTCCTGTTGGTTCAGCTATTACCAGTTACGCTAGAAACTTTACAATTAGAGCCGCACAAGCAAATTATCATGGTGTAAATAAAAGAGGTTTCATTTATGCTGATACAGACAGTATACATTGTGACTTACCACCAGAACAGATTACAGGTATTAAAGTACATGAAACAGATTTTTGTGCATGGAAACTTGAATCTTGTTGGGATAAAGCTATTTTTGCAAGACAGAAAACGTATATTGAACATGTTACACATGAAGATTTGCAAAAGATTGAAGAACCATACAACAACATCAAGTGTGCGGGAATGCCACAGCGATGCAAAGACTTGTTTGAATTGTCAATGTCTGGCAAAGCTGTGTATGAAGATTACAAAGAAAATACACCAGTAAACAGATTTCTTTTTAACCAAGTCACACACGAACCTATTGTAAGAACTTTTGACGATTTCAAAATAGGATTAAACGTACCATGTAAATTAATTCCAAAGCGAATAGAGGGTGGTGTTTTACTTGTTGAATCAACGTATCAAATGCGGTAA

Genome Context

Genome Context

Gene Ontology

Description Category Evidence (source)
GO:0003677 DNA binding Molecular Function IEA:UniProtKB-KW (UniProt)
GO:0003887 DNA-directed DNA polymerase activity Molecular Function IEA:UniProtKB-KW (UniProt)
GO:0004527 exonuclease activity Molecular Function IEA:UniProtKB-KW (UniProt)
GO:0000166 nucleotide binding Molecular Function IEA:InterPro (UniProt)
GO:0006260 DNA replication Biological Process IEA:UniProtKB-KW (UniProt)
GO:0039693 viral DNA genome replication Biological Process IEA:UniProtKB-KW (UniProt)

Tertiary structure

PDB ID
a4ddb0ece61ef05ee963fd7d63cdf56222bd1779ed9cb4a76398ad9100e5534b
ColabFold
Source ColabFold
Method ColabFold
Resolution 0,9351
Oligomeric State monomer
Download PDB
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50