Protein

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Genbank accession

YP_010657804.1 [GenBank]

Protein name

tail spike protein

RBP type

Evidence UniProt/TrEMBL

Probability 1,00

Evidence GenBank

Probability 1,00

TSP

Evidence RBPdetect

Probability 0,88

Protein sequence

MGMNSHIPFDADNDWTLDPYHCNRSNDPLVDKVIGNAYAVVRAVYCNLGNLKLLYDFLNTYGMVLGVKSEAELKKLNKLAKYARVYGFADTGDRQVTDYLYVPDDTSGIRPDDQTATGSWIKVSTSGSGSGGTGGGSGSYIPYVYANGSALGGETSFKVPAEALGVPFIIINGSVQYIGYGFSFNPANSTVTLSNPLVQGDEVIALTSAAPASPDNPNVSNWVQVNWLYNNGAAVGGEQVITVPYNFKDVPAVYKNGERYYKNLQTKSYVYDPSTRTVTMTELLAQGDRVIITLGGESASLEITDRTTQEVARANNVKDTDVVLSSSTNVVITDKKVLYDVNAQKYWDLPNLPPNVYIVKVEGNKLIYNPGAVVIDLLEPANPLVIVEPVLSRLGAETGNPMAGTFEKGATVDSAAKSVGSTMEGKLYRWEGALPKTVRAGDTPSSSGGIGSGKWVEITNATLRSQLASTGGAAMVKASDGRTVEQWLVQSDSASFRAKNMAKLAWCDYQVHNRGSLKCCFLGDSMTAGFDRTSSDTIPAQDGDWATRASMNYPYRFASYLPEQSGCSVYITMRAISGYTAKQAYEEALWQSNPNCDIVFIMYAINDSGGVAGATLDLYMEYMEKLIRRYIDWGCAVVVQRPSGGGQGAGNPAWLHWAKRMQMVARVYGCPVFDAHEVMLNRHYAAVQSDGTHYNSMGYAIHGEKLASMLMAGGLLDTYKPVVNETTVWTGMMSDHIGWCDARGNIGTGRSDGAYTRDKVTGVLQAGKATICTFSFYLDAEAAHIYGKLDGLINTIYTNGYWWNNGNKPYYQYAVDIDNSFGASLQRVNKSANNYEGMPGSRKFVGRLIGRGWHTITLFTNLQGEALKDAFVNSITVQPIPIGLSTEQMWGQDEERRYRVVHTRRMPSPSGQGGTLPVAVALTGFQMRAPQSFLGTGPGTNAVPAPYFYNTVPGKLKVYNEKGDYIEWLVYKDGSSGLKWKGKVLTHSFADVASVPTLTAYMGTAKQNVIVAAGSSGANQPLENIYDYNAGLQEQTGNPSTDLSWKGGIYLVFTLAWPSTAPTGYWTIELEGSDWFGNSESAVGCF

Physico‐chemical properties

protein length:	1086 AA
molecular weight:	117901,16480 Da
isoelectric point:	5,76668
aromaticity:	0,10681
hydropathy:	-0,23923

Domains

Domains [InterPro]

DC_0041
STR
27–223

DC_0041 DC_1596 DC_0640

G3DSA:3.30.2020.50
ATT
295–380

G3DSA:3.30.2020.50 G3DSA:2.10.10.80 IPR036514

IPR040775
RBD
405–458

IPR040775 SSF52266

IPR013830
ENZ
521–701

IPR013830

cd00229
ENZ
521–708

cd00229

YP_010657804.1

1 1086

Architecture

STR

ATT

STR

ATT

STR

RBD

STR 27-223 | STR 271-294 | ATT 295-380 | STR 381-399 | ATT 400-470 | STR 471-711 | RBD 712-1083 |

Legend: ATT STR RBD CBM LEC ENZ CHP LNK TAS TTP UNK Unmapped

Domains [InterPro]

Domain ID	Category	Cluster	Start	End	Layer	Name	Pref Zone	Confidence	Evidence	Support
DC_0041	STR	DC_0041	27	223	Novel HMM	DC_0041	Central	Low	Positional only	179 proteins / 179 hits
DC_1596	STR	DC_1596	271	632	Novel HMM	DC_1596	Central	Low	Positional only	84 proteins / 84 hits
G3DSA:3.30.2020.50	ATT	G3DSA:3.30.2020.50	295	380	Merged direct domain	G3DSA:3.30.2020.50	N-terminal	Low	Positional only	289 proteins / 289 hits
G3DSA:2.10.10.80	ATT	G3DSA:2.10.10.80	400	470	Merged direct domain	G3DSA:2.10.10.80	N-terminal	Low	Positional only	383 proteins / 383 hits
IPR040775	RBD	DC_0821	405	458	InterPro cluster	Tail spike TSP1/Gp66, N-terminal domain	Central	High	Text match	1281 proteins / 1285 hits
IPR036514	STR	IPR036514	501	711	Merged direct domain	SGNH hydrolase superfamily	Central	Low	Positional only	180 proteins / 180 hits
SSF52266	STR	SSF52266	519	710	Merged direct domain	SSF52266	Central	Low	Positional only	227 proteins / 227 hits
IPR013830	ENZ	DC_0001	521	701	InterPro cluster	SGNH hydrolase-type esterase domain	C-terminal	High	Text match	480 proteins / 783 hits
cd00229	ENZ	DC_0001	521	708	InterPro cluster	cd00229	C-terminal	High	Text match	480 proteins / 783 hits
DC_0640	RBD	DC_0640	712	1083	Novel HMM	DC_0640	C-terminal	Low	Positional only	15 proteins / 15 hits

Tail Spike Domain Segmentation

This protein has been segmented into three structural domains: N-terminal, central domain, and C-terminal.

Domain Layout

N-terminal

Central

C-terminal

YP_010657804.1

1 1086

Domain	Start	End	Length (AA)	Confidence
N-terminal	1	493	493	0,9561
Central domain	494	1011	519	0,9297
C-terminal	1012	1086	74	0,3378

Legend: N-terminal Central domain C-terminal

3D Structure with Domain Coloring

The structure is colored according to the domain segmentation: N-terminal (blue), Central (green), C-terminal (pink).

Domain Coloring

N-terminal
1-493

Central
494-1011

C-terminal
1012-1086

Taxonomy

	Name	Taxonomy ID	Lineage
Phage	Shigella virus Moo19 [NCBI]	2886042	Uroviricota > Caudoviricetes > Schitoviridae > Moovirus > Moovirus moo
Host	Shigella flexneri [NCBI]	623	cellular organisms > Bacteria > Pseudomonadati > Pseudomonadota > Gammaproteobacteria > Enterobacterales

Coding sequence (CDS)

Genbank protein accession

YP_010657804.1 [NCBI]

Genbank nucleotide accession

NC_070850.1 [NCBI]

CDS location

range 65719 -> 68979
strand -

CDS

ATGGGTATGAACTCTCACATTCCATTTGATGCAGACAATGACTGGACTCTCGACCCATATCATTGCAATCGCTCCAACGACCCACTTGTCGATAAGGTGATTGGTAATGCCTATGCCGTGGTTCGTGCAGTCTACTGTAACCTGGGTAACCTGAAGTTACTGTATGACTTCCTGAATACCTACGGTATGGTTCTGGGTGTTAAGTCAGAAGCTGAATTAAAGAAGCTGAACAAGTTGGCTAAGTATGCCCGTGTCTATGGCTTCGCTGATACAGGTGACCGTCAGGTAACTGATTACCTGTACGTACCTGATGATACTTCTGGTATTCGCCCAGATGACCAAACTGCTACAGGCTCCTGGATTAAAGTATCTACCTCTGGTTCCGGCAGTGGTGGTACAGGTGGTGGTTCCGGTTCCTACATTCCATACGTTTATGCTAATGGCTCTGCATTGGGTGGGGAGACTTCATTTAAAGTTCCTGCTGAAGCACTGGGTGTACCCTTCATTATCATTAACGGCTCGGTTCAGTACATTGGTTATGGCTTCAGCTTTAACCCAGCTAACTCCACCGTTACCCTTAGTAACCCACTGGTTCAGGGTGATGAAGTTATTGCACTGACTTCTGCTGCTCCAGCAAGCCCGGATAACCCTAATGTATCCAACTGGGTTCAGGTTAACTGGCTCTATAACAACGGTGCTGCTGTAGGTGGCGAACAGGTAATTACTGTTCCTTATAACTTTAAAGATGTTCCTGCCGTTTATAAAAATGGTGAACGTTACTATAAGAACCTGCAAACCAAGTCTTACGTTTATGACCCAAGTACTCGTACTGTTACTATGACTGAGCTTCTTGCTCAGGGTGACCGTGTGATTATTACTCTGGGTGGTGAATCTGCCAGTCTTGAGATTACTGACCGAACCACGCAAGAAGTAGCTCGTGCAAACAACGTAAAGGATACTGATGTTGTTCTGTCTTCCTCTACTAATGTAGTGATTACTGACAAGAAAGTTCTTTACGATGTGAATGCTCAGAAGTACTGGGATTTGCCTAACCTGCCACCTAACGTTTATATCGTTAAGGTAGAAGGTAACAAGCTGATTTATAACCCAGGTGCTGTTGTTATTGACCTGTTAGAACCAGCAAACCCACTGGTAATCGTTGAGCCTGTTCTTTCCCGTCTGGGGGCTGAGACTGGTAATCCAATGGCTGGTACTTTCGAGAAAGGTGCAACTGTTGACTCTGCTGCTAAGTCAGTTGGTTCTACTATGGAAGGTAAGCTATATCGTTGGGAAGGTGCATTACCTAAGACTGTACGTGCCGGGGATACTCCATCTTCTTCTGGTGGAATTGGTTCTGGTAAGTGGGTAGAGATTACTAATGCAACTTTACGCAGCCAGCTTGCAAGTACTGGTGGTGCTGCAATGGTTAAAGCCTCTGACGGGCGTACTGTTGAGCAATGGCTTGTTCAGTCTGACTCTGCATCTTTCCGTGCAAAGAACATGGCTAAGCTGGCATGGTGCGATTATCAAGTTCATAACCGTGGTTCCCTGAAGTGCTGCTTCCTGGGTGACTCCATGACTGCTGGGTTTGACCGTACTTCCTCAGATACTATTCCTGCTCAGGATGGTGACTGGGCTACCCGTGCTTCTATGAACTACCCATACCGTTTTGCTAGTTACTTGCCTGAACAGTCTGGTTGTTCCGTCTATATTACTATGAGAGCAATTTCAGGTTACACGGCGAAACAGGCTTATGAAGAGGCACTGTGGCAGTCTAATCCAAACTGCGACATTGTGTTCATCATGTATGCAATTAACGATTCCGGTGGTGTAGCTGGTGCAACTCTTGACCTCTACATGGAATACATGGAGAAGCTCATTCGTCGTTATATCGACTGGGGCTGTGCTGTAGTTGTTCAACGTCCATCTGGTGGTGGTCAGGGTGCTGGTAACCCAGCGTGGCTGCATTGGGCTAAACGTATGCAGATGGTAGCTCGTGTTTACGGTTGCCCTGTATTTGATGCTCATGAAGTAATGCTTAACCGTCACTATGCTGCTGTTCAGTCTGATGGTACTCACTACAACTCTATGGGTTATGCAATTCACGGTGAGAAGCTGGCATCCATGCTTATGGCAGGTGGACTCCTGGATACCTATAAACCAGTGGTTAATGAAACTACTGTGTGGACGGGTATGATGTCTGACCATATTGGTTGGTGTGATGCACGAGGTAATATTGGTACTGGTCGTTCTGACGGAGCGTACACTCGTGACAAAGTTACTGGTGTACTCCAGGCGGGTAAAGCAACCATCTGTACCTTTAGCTTCTATCTGGATGCAGAAGCTGCACATATCTACGGTAAGCTGGATGGTTTAATTAATACCATTTACACCAATGGATACTGGTGGAATAACGGCAACAAGCCTTATTACCAGTATGCAGTAGATATTGATAACTCTTTTGGTGCATCTTTACAGCGTGTTAATAAGTCAGCTAACAACTACGAGGGAATGCCAGGCTCACGTAAGTTTGTGGGTCGTTTGATTGGTCGTGGTTGGCACACTATTACTCTGTTTACCAATTTGCAAGGTGAAGCACTGAAAGATGCTTTTGTTAACAGCATTACTGTTCAGCCAATCCCAATTGGTCTGTCAACTGAGCAGATGTGGGGACAGGATGAAGAACGCCGTTATCGTGTAGTACACACTCGTCGTATGCCTTCTCCATCTGGGCAGGGTGGTACGCTACCTGTGGCAGTAGCATTGACTGGCTTCCAAATGAGAGCACCTCAGAGCTTCTTGGGTACTGGTCCGGGTACGAATGCAGTTCCTGCTCCTTATTTCTACAATACGGTTCCAGGCAAACTGAAGGTATATAACGAGAAAGGCGACTACATCGAGTGGCTTGTCTACAAGGATGGTTCGTCTGGTCTTAAGTGGAAAGGCAAAGTTCTTACCCACAGTTTTGCTGATGTTGCCTCTGTACCAACCTTAACTGCATACATGGGTACAGCTAAACAAAACGTTATTGTGGCAGCGGGTAGTTCTGGTGCAAACCAACCATTGGAAAATATTTATGACTACAATGCAGGTTTGCAAGAACAAACAGGTAACCCATCTACTGACCTTTCCTGGAAAGGTGGTATTTATCTGGTATTTACTCTGGCATGGCCTAGCACTGCTCCAACTGGTTATTGGACCATTGAGCTTGAGGGTAGTGATTGGTTTGGTAACTCTGAGTCTGCTGTAGGTTGCTTCTAA

Genome Context

Tertiary structure

1 / 3

PDB ID

Source

Method

Resolution

Oligomeric State

Protein

Domains

Domains [InterPro]

Domains [InterPro]

Tail Spike Domain Segmentation

Tail Spike Domain Segmentation

3D Structure with Domain Coloring

Domain Coloring

Taxonomy

Coding sequence (CDS)

Coding sequence (CDS)

Genome Context

Genome Context

Tertiary structure

Predicted Aligned Error (PAE)