Protein

View in Explore

UniProt accession

A0A6B9WJD5 [UniProt]

Protein name

BIG2 domain-containing protein

RBP type

TSP

Evidence RBPdetect2

Probability 0,74

Protein sequence

MFPIPIFTIMTSTGVVPLPAGIVKKVITLDYPDNAGNSNSSLAILLNDGRLFTQGANLFGEIADGTRSARFNNFHLASTVVADVFTADRCFVIKTNSGGWQYSGLTAGLVGSIAAGGADACVTTWTSFPSVITGTISLANLKEVKGGYNNTLWLMNSGVLYGSGQNTVGSLGASTTNEVSTPRQITSAAVAFDAGYNQCSYVNNVGTLRVCGASKGLAGNNNTTKAFVNATISTTETVYVKDYINTVSQTIVVGDTSGGTGTTNYLYVRSNTETTYTKLDTFAAGFSTWKFPPSRHSFFVGINNSLWAIGKNYTANLGLGYDSASGDPLQVGKPVKPEGVGSWDINKLTSVHTLNMDVTNQLGYQGTFFVYNGSMYYSGIWKDGKASYLFNSGLNYNKFTPIASSVITGDVLATSLTTDSLGICIVGGTKQLTHSVSPEGGKLFNIKYTSSAPANMTISSTGLMTFQAEGGFDAGMTALNAEGTTLSDISGGYASTLSVYTPSLSAMDVGTTQTMVAEITPTGAASLPGMVVEYTTTDPSVATVDPTTGVITGVGDGGCRIGCTATYQGVVTASDSSYLTVNAVAGKELAPSPSSSLTVLNGYFNHSADGAITFPTLSGTVTPANFVVKVDDVVVPSSKVIFRNKAFSTVDSYPAGEYRLAIEFASASVVNNVEVSMEANPDLLELWGGNRIGYSTSPASQFLKGCANLRRITSDCFSNTSYTGTSISGIFSGCTSLTAIPEGLFSDTLFPSMTTMSSTFEGCTSLTSIPSDLFKNLSKVTRYSYTFKNCTSLAEVPAGMFDNIPTKVTSLTATFQGCLALTDFNKIFNDNPGLTVCGQRGALSSFFSGCTNLTGTGVTLTSTLGGAANSYLFRYCTKLSDYNNIPSGYK

Physico‐chemical properties

protein length:	890 AA
molecular weight:	93167,38570 Da
isoelectric point:	5,35403
aromaticity:	0,09888
hydropathy:	0,07090

Domains

Domains [InterPro]

DC_0065
STR
1–291

DC_0065 DC_0179 G3DSA:2.60.40.1080 DC_0356 IPR032675

IPR009091
STR
34–354

IPR009091 DC_1711 DC_0669

IPR009091
STR
39–333

IPR009091 IPR008964 DC_0669

IPR003343
STR
505–565

IPR003343

A0A6B9WJD5

1 890

Architecture

STR

STR 1-668 | STR 673-889 |

Legend: ATT STR RBD CBM LEC ENZ CHP LNK TAS TTP UNK Unmapped

Domains [InterPro]

Domain ID	Category	Cluster	Start	End	Layer	Name	Pref Zone	Confidence	Evidence	Support
DC_0065	STR	DC_0065	1	291	Novel HMM	DC_0065	Central	Low	Positional only	140 proteins / 140 hits
IPR009091	STR	IPR009091	34	354	Merged direct domain	Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II	Central	Low	Positional only	141 proteins / 141 hits
IPR009091	STR	IPR009091	39	333	Merged direct domain	Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II	Central	Low	Positional only	141 proteins / 141 hits
DC_0179	STR	DC_0179	342	501	Novel HMM	DC_0179	Central	Low	Positional only	58 proteins / 58 hits
DC_1711	RBD	DC_1711	482	585	Novel HMM	DC_1711	C-terminal	Low	Positional only	141 proteins / 141 hits
G3DSA:2.60.40.1080	STR	G3DSA:2.60.40.1080	502	583	Merged direct domain	G3DSA:2.60.40.1080	Central	Low	Positional only	18 proteins / 18 hits
IPR008964	RBD	IPR008964	503	571	Merged direct domain	Invasin/intimin cell-adhesion fragments	C-terminal	Low	Positional only	2 proteins / 2 hits
IPR003343	STR	DC_0008	505	565	InterPro cluster	Bacterial Ig-like domain, group 2	C-terminal	Medium	Text match	304 proteins / 473 hits
DC_0356	STR	DC_0356	585	668	Novel HMM	DC_0356	Central	Low	Positional only	24 proteins / 24 hits
IPR032675	STR	IPR032675	673	883	Merged direct domain	Leucine-rich repeat domain superfamily	Central	Low	Positional only	55 proteins / 55 hits
DC_0669	RBD	DC_0669	687	837	Novel HMM	DC_0669	C-terminal	Low	Positional only	46 proteins / 46 hits
DC_0669	RBD	DC_0669	820	889	Novel HMM	DC_0669	C-terminal	Low	Positional only	46 proteins / 46 hits

Tail Spike Domain Segmentation

This protein has been segmented into three structural domains: N-terminal, central domain, and C-terminal.

Domain Layout

N-terminal

Central

C-terminal

A0A6B9WJD5

1 890

Domain	Start	End	Length (AA)	Confidence
N-terminal	1	24	24	0,6885
Central domain	25	244	221	0,5919
C-terminal	245	890	645	0,0693

Note: Constraints were applied during segmentation.
Fixed 22 C-terminal predictions appearing before Central domain

Legend: N-terminal Central domain C-terminal

3D Structure with Domain Coloring

The structure is colored according to the domain segmentation: N-terminal (blue), Central (green), C-terminal (pink).

Domain Coloring

N-terminal
1-24

Central
25-244

C-terminal
245-890

Taxonomy

	Name	Taxonomy ID	Lineage
Phage	Escherichia phage ukendt [NCBI]	2696458	Uroviricota > Caudoviricetes > Stephanstirmvirinae > Phapecoctavirus ukendt >
Host	Escherichia coli K-12 [NCBI]	83333	Bacteria > Proteobacteria > Gammaproteobacteria > Enterobacteriales > Enterobacteriaceae > Escherichia

Coding sequence (CDS)

No CDS data available.

Genome Context

Tertiary structure

PDB ID

4e544610f7b702a83a9c41d7d93ba1096b93fd07d88cdf48ead62ecac7eb5a83

ColabFold

Source ColabFold

Method ColabFold

Resolution 0,2923

Oligomeric State monomer

Download PDB

Model Confidence

Very high
pLDDT > 90

High
90 > pLDDT > 70

Low
70 > pLDDT > 50

Very low
pLDDT < 50

Protein

Domains

Domains [InterPro]

Domains [InterPro]

Tail Spike Domain Segmentation

Tail Spike Domain Segmentation

3D Structure with Domain Coloring

Domain Coloring

Taxonomy

Coding sequence (CDS)

Coding sequence (CDS)

Genome Context

Genome Context

Tertiary structure

Predicted Aligned Error (PAE)

Model Confidence