Protein

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UniProt accession
A0AB74UQ03 [UniProt]
Protein name
Tail spike protein
RBP type
TSP
Evidence UniProt/TrEMBL
Probability 1,00
TF
Evidence GenBank
Probability 1,00
TSP
Evidence DepoScope
Probability 1,00
TSP
Evidence RBPdetect
Probability 0,91
TSP
Evidence RBPdetect2
Probability 0,95
Protein sequence
MALIRLVAPERVFSDLASMVAYPNFQVQDKITLLGSAGGDFTFTTTASVVDNGTVFAVPGGYLLRKFVGPAYSSWFSNWAGIVTFMSAPNRHLVVDTVLQATSVLNIKSNSTLEFTDTGRILPDAAVARQVLNIIGSAPSVFVPLAADAAAGSKVITVAAGALSAVKGTYLYLRSNKLCDGGPNTHGVKISQIRKVVGVSTSGGVTSIRLDKALHYNYHLSDAAEVGIPTMVENVTLVSPYINEFGYDDLNRFFTIGISANFAADLHIQGGVIIGNKRPGASDIEGRSAIKFNNCVDSTVKGTYFYNIGWYGVEVLGCSEDTEVHDIHAMDVRHAISLNWQSTADGGKWGEPIEFLGVNCEAYNTTLAGFDTHDIGKRVKFVRCVSYDSADDGFQARTNGVEYLNCRAYRAAMDGFASNTGVAFPIYRECLAYDNVRSGFNCSYGGGYVYDCEAHGSQNGVRINGGRVKGGRYTRNSSSHIFVTKDVAETAQTSLEIDGVSMRYDGTGRAVYFHGTMGINPTLVSMSNNDMTGHGLFWALLSGYTVQPTPPRMSRNLLDDTGIRGVATLVAGEATVNARVRGNFGSVANSFKWASEVKLTRLTFPASAGALTVTGVAQNQDVPTPNPDLNSFVIRSSNAADVSQVAWEVYL
Physico‐chemical
properties
protein length:651 AA
molecular weight: 69796,68990 Da
isoelectric point:6,23969
aromaticity:0,09831
hydropathy:-0,00676

Domains

Domains [InterPro]
IPR057094
ENZ
1–71
IPR057094 DC_0267 DC_1484
IPR057095
ENZ
141–230
IPR057095 IPR011050 IPR056204
IPR006626
Unmapped
263–294
IPR006626 IPR006626 IPR012334
IPR006626
Unmapped
376–398
IPR006626 IPR006626
A0AB74UQ03
1 651
Architecture
ENZ
ATT
ENZ
STR
ENZ 1-71 | ATT 72-145 | ENZ 146-179 | STR 180-651
Legend: ATT STR RBD CBM LEC ENZ CHP LNK TAS TTP UNK Unmapped

Tail Spike Domain Segmentation

Tail Spike Domain Segmentation

This protein has been segmented into three structural domains: N-terminal, central domain, and C-terminal.

Domain Layout
N-terminal
Central
C-terminal
A0AB74UQ03
1 651
Domain Start End Length (AA) Confidence
N-terminal 1 78 78 0,9876
Central domain 79 582 505 0,9849
C-terminal 583 651 68 0,9471
Legend: N-terminal Central domain C-terminal
3D Structure with Domain Coloring

The structure is colored according to the domain segmentation: N-terminal (blue), Central (green), C-terminal (pink).

Domain Coloring
N-terminal
1-78
Central
79-582
C-terminal
583-651

Taxonomy

  Name Taxonomy ID Lineage
Phage Klebsiella phage HenuGS
[NCBI] 		3350566 Uroviricota > Caudoviricetes > Autographivirales > Slopekvirinae > Drulisvirus
Host Klebsiella pneumoniae
[NCBI] 		573 cellular organisms > Bacteria > Pseudomonadati > Pseudomonadota > Gammaproteobacteria > Enterobacterales

Coding sequence (CDS)

Coding sequence (CDS)
Genbank protein accession
XHV15869.1 [NCBI]
Genbank nucleotide accession
PQ362313 [NCBI]
CDS location
range 42055 -> 44010
strand +
CDS
ATGGCATTAATTAGATTAGTAGCTCCAGAGCGGGTGTTCTCCGACTTGGCGAGCATGGTAGCATACCCAAACTTTCAGGTGCAGGACAAGATTACCCTGCTGGGCAGCGCCGGTGGGGATTTCACCTTTACTACTACTGCGTCGGTAGTGGATAACGGAACCGTGTTTGCTGTACCCGGTGGGTACCTGCTACGTAAATTCGTGGGCCCAGCATACAGCTCCTGGTTCAGCAACTGGGCGGGCATAGTCACGTTCATGAGCGCGCCTAATAGGCACCTGGTTGTGGACACGGTCCTGCAGGCCACGAGTGTGCTCAACATCAAAAGCAACTCTACGCTAGAGTTTACCGATACCGGAAGAATCCTACCGGATGCTGCGGTTGCACGTCAAGTGCTTAATATTATCGGCTCGGCACCCTCGGTGTTCGTACCGTTAGCAGCGGATGCCGCAGCGGGCAGTAAAGTCATTACGGTGGCTGCTGGGGCTTTGTCTGCGGTAAAAGGTACGTACTTGTATCTTCGCTCTAACAAGCTGTGTGATGGTGGTCCTAACACCCACGGTGTAAAGATTTCCCAGATTAGGAAAGTGGTGGGGGTTAGCACCTCCGGTGGCGTCACCAGTATTCGGCTGGATAAAGCGCTGCACTATAACTACCACCTGTCTGATGCCGCGGAAGTAGGTATCCCGACAATGGTGGAGAACGTAACCTTAGTATCCCCGTACATCAACGAGTTCGGCTACGACGATTTGAACCGGTTCTTTACTATCGGTATCTCTGCCAACTTTGCCGCGGACTTGCACATCCAGGGCGGGGTTATTATTGGCAACAAACGCCCCGGGGCTTCTGATATAGAAGGGCGTAGTGCTATCAAGTTCAATAACTGCGTAGACAGTACCGTTAAGGGTACGTACTTCTACAACATCGGATGGTACGGGGTAGAGGTGCTCGGCTGCTCAGAGGACACGGAAGTACACGATATCCACGCTATGGACGTACGCCACGCAATCTCTCTGAACTGGCAGAGCACTGCGGACGGGGGCAAGTGGGGAGAGCCTATCGAGTTCTTAGGCGTTAACTGCGAAGCCTACAACACAACCCTGGCTGGGTTTGATACTCACGACATTGGTAAGCGTGTGAAGTTCGTTCGCTGCGTTTCGTACGACAGTGCTGACGATGGGTTCCAAGCGCGCACTAACGGGGTGGAGTACTTGAACTGTCGAGCTTACCGTGCAGCTATGGACGGGTTCGCCTCCAACACCGGTGTAGCCTTCCCTATCTATAGGGAGTGCCTAGCTTATGACAACGTACGCTCTGGCTTTAACTGCTCGTACGGCGGTGGCTACGTTTATGACTGCGAGGCTCACGGTAGCCAGAATGGTGTGCGAATCAACGGGGGCCGTGTTAAGGGTGGTCGGTACACCCGCAACTCCAGCTCTCACATCTTCGTCACTAAGGACGTAGCTGAGACAGCGCAGACATCCCTGGAGATTGATGGCGTGAGCATGCGCTACGACGGTACCGGGAGAGCTGTGTACTTCCACGGGACTATGGGCATTAACCCTACCCTGGTATCTATGTCCAATAACGACATGACCGGTCACGGCTTGTTCTGGGCATTGCTGAGCGGCTACACCGTTCAACCTACGCCTCCGCGCATGTCCAGGAACTTACTGGATGACACAGGTATCCGTGGAGTGGCAACGCTGGTTGCTGGCGAGGCTACAGTCAACGCCCGTGTACGCGGAAACTTTGGCAGCGTAGCTAACTCCTTCAAGTGGGCGTCCGAGGTTAAGTTGACGCGGTTGACCTTTCCCGCTAGTGCTGGGGCCTTGACGGTTACTGGCGTAGCTCAGAACCAGGATGTGCCTACACCTAATCCGGACCTAAACAGCTTCGTGATTAGGAGCAGTAACGCAGCGGACGTATCCCAGGTAGCCTGGGAGGTGTATCTCTAA

Genome Context

Genome Context

Gene Ontology

Description Category Evidence (source)
GO:0098015 virus tail Cellular Component IEA:UniProtKB-KW (UniProt)
GO:0098994 symbiont entry into host cell via disruption of host cell envelope Biological Process IEA:UniProtKB-KW (UniProt)
GO:0098996 symbiont entry into host cell via disruption of host cell glycocalyx Biological Process IEA:UniProtKB-KW (UniProt)

Tertiary structure

PDB ID
fd577512be1c4db9d4bc56c68c8f0f3237cdb15171d07858024500313f1ab0eb
ESMFold
Source ESMFold
Method ESMFold
Resolution 0,8575
Oligomeric State monomer
Download PDB
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50