Protein

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UniProt accession

A0A5B9NE60 [UniProt]

Protein name

Probable tail spike protein

RBP type

Evidence GenBank

Probability 1,00

TSP

Evidence DepoScope

Probability 1,00

TSP

Evidence RBPdetect

Probability 0,91

TSP

Evidence RBPdetect2

Probability 0,95

Protein sequence

MSTITQFPSGNTQYRIEFDYLARTFVVVTLVNSSNPALNRVLEVGRDYRFLNPTMIEMLVDQSGFDIVRIHRQTGTDLVVDFRNGSVLTSSDLTNAELQAIHIAEEGRDQTVDLAKEYADAAGSSAGNAKDSEDEARRIAESIKTAGLLGYVTRRSFEKGFNITAWNEALLWEADGNYYCWDGTLPKNVPVGSTPETAGGIGNGKWVSIGDAALRGQISDPEGATKYPELQIARWRDNGDPRGWGAIGDGVTDDTLALQACFDTATCDIDLGGKTYLVRKNPTLAATYPNEPDFSDGSYNYSPCLALVGKKNIKIHNGALIVETHGLDAISLIACEHVTVDLTIKGPGIFPAIDTPTGYAEKGEANFGYDSSLLLAPNNALDTSAYTGGAYAGVAGQFPKYNADGSQASGWQSTWGTFLGGYIGSWACGVKVQRACRGILINDCDISGFNFGAVGIGIRNTAAAYGASDYTTDADIPDGVMVINTRIRKCYSAGIYVLSGYRLNYMANNIEDIGHPNGNDALNASYDPGYGITHGRNRRIRNVTITENMIRNCRRKCIDFHGGGQAIIAKNHCLEHGVVGIYAKCGPGWSPNYEPYNLIIADNYVRSRDVPASETTGPLIGAKYTRSIDVGGGGEATQATYPDPFVKIHNNYCELRAYDGVAISTGAGDDNYNVFMDIDVSHNTVVLKCNTPNNFAEGIGINAGAASNKVYRGQRVKLIGNSIKQLNTLNLTYRSAGYKIQGIPKSLIMHGNTLDLNVSTQSCKLCDFVIDSRINYSFEGNQVLSFSARDSATLQEVWLYDNMKITRPAAAAAATISGNLFRGIWQVCIAGTGDAFGAKQTQFASTGSGGTGFDVVRSATTGFIATFGIGASGLIVPAVTQESQVQINLKLVSSLDSVA

Physico‐chemical properties

protein length:	899 AA
molecular weight:	96438,72450 Da
isoelectric point:	5,40155
aromaticity:	0,09010
hydropathy:	-0,18765

Domains

Domains [InterPro]

DC_0041
STR
1–136

DC_0041 G3DSA:2.10.10.80 G3DSA:3.30.750.60 IPR006626 IPR006626 IPR012334

IPR005604
ATT
10–113

IPR005604 IPR040775 IPR011050 DC_0622

DC_1280
ATT
105–288

DC_1280 IPR039448 IPR006626 IPR006626

IPR006626
Unmapped
540–562

IPR006626

A0A5B9NE60

1 899

Architecture

ATT

STR

RBD

ATT 1-290 | STR 291-824 | RBD 825-899

Legend: ATT STR RBD CBM LEC ENZ CHP LNK TAS TTP UNK Unmapped

Domains [InterPro]

Domain ID	Category	Cluster	Start	End	Layer	Name	Pref Zone	Confidence	Evidence	Support
DC_0041	STR	DC_0041	1	136	Novel HMM	DC_0041	Central	Low	Positional only	179 proteins / 179 hits
IPR005604	ATT	DC_0240	10	113	InterPro cluster	Bacteriophage T7 tail fibre protein-like, N-terminal domain	Central	Medium	Text match	1326 proteins / 1328 hits
DC_1280	ATT	DC_1280	105	288	Novel HMM	DC_1280	N-terminal	Low	Positional only	90 proteins / 90 hits
G3DSA:2.10.10.80	ATT	G3DSA:2.10.10.80	150	220	Merged direct domain	G3DSA:2.10.10.80	N-terminal	Low	Positional only	383 proteins / 383 hits
IPR040775	RBD	DC_0821	153	211	InterPro cluster	Tail spike TSP1/Gp66, N-terminal domain	Central	High	Text match	1281 proteins / 1285 hits
G3DSA:3.30.750.60	ATT	G3DSA:3.30.750.60	240	290	Merged direct domain	G3DSA:3.30.750.60	N-terminal	Low	Positional only	2 proteins / 2 hits
IPR011050	STR	IPR011050	241	581	Merged direct domain	Pectin lyase fold/virulence factor	Central	Low	Positional only	572 proteins / 572 hits
IPR006626	Unmapped	-	436	460	InterPro	Parallel beta-helix repeat	-	-	-	-
IPR006626	Unmapped	-	477	499	InterPro	Parallel beta-helix repeat	-	-	-	-
IPR039448	ENZ	DC_0799	480	607	InterPro cluster	Right handed beta helix domain	C-terminal	High	Text match	178 proteins / 183 hits
IPR012334	STR	IPR012334	523	824	Merged direct domain	Pectin lyase fold	Central	Low	Positional only	867 proteins / 867 hits
IPR006626	Unmapped	-	540	562	InterPro	Parallel beta-helix repeat	-	-	-	-
DC_0622	RBD	DC_0622	605	899	Novel HMM	DC_0622	C-terminal	Low	Positional only	16 proteins / 16 hits
IPR006626	Unmapped	-	643	665	InterPro	Parallel beta-helix repeat	-	-	-	-
IPR006626	Unmapped	-	811	857	InterPro	Parallel beta-helix repeat	-	-	-	-

Tail Spike Domain Segmentation

This protein has been segmented into three structural domains: N-terminal, central domain, and C-terminal.

Domain Layout

N-terminal

Central

C-terminal

A0A5B9NE60

1 899

Domain	Start	End	Length (AA)	Confidence
N-terminal	1	253	253	0,9928
Central domain	254	784	532	0,9951
C-terminal	785	899	114	0,9388

Legend: N-terminal Central domain C-terminal

3D Structure with Domain Coloring

The structure is colored according to the domain segmentation: N-terminal (blue), Central (green), C-terminal (pink).

Domain Coloring

N-terminal
1-253

Central
254-784

C-terminal
785-899

Taxonomy

	Name	Taxonomy ID	Lineage
Phage	Escherichia phage Peacock [NCBI]	2591100	Viruses > Duplodnaviria > Heunggongvirae > Uroviricota > Caudoviricetes
Host	Escherichia coli [NCBI]	562	cellular organisms > Bacteria > Pseudomonadati > Pseudomonadota > Gammaproteobacteria > Enterobacterales

Coding sequence (CDS)

No CDS data available.

Genome Context

Gene Ontology

	Description	Category	Evidence (source)
GO:0098015	virus tail	Cellular Component	IEA:UniProtKB-KW (UniProt)
GO:0098671	adhesion receptor-mediated virion attachment to host cell	Biological Process	IEA:UniProtKB-KW (UniProt)
GO:0098994	symbiont entry into host cell via disruption of host cell envelope	Biological Process	IEA:UniProtKB-KW (UniProt)
GO:0098996	symbiont entry into host cell via disruption of host cell glycocalyx	Biological Process	IEA:UniProtKB-KW (UniProt)

Tertiary structure

PDB ID

a3b4b2df992ffc2dca0c525134c1f01d4fc40679200492ebcdac2ca2a1a1e0d7

ESMFold

Source ESMFold

Method ESMFold

Resolution 0,7105

Oligomeric State monomer

Download PDB

Model Confidence

Very high
pLDDT > 90

High
90 > pLDDT > 70

Low
70 > pLDDT > 50

Very low
pLDDT < 50

Protein

Domains

Domains [InterPro]

Domains [InterPro]

Tail Spike Domain Segmentation

Tail Spike Domain Segmentation

3D Structure with Domain Coloring

Domain Coloring

Taxonomy

Coding sequence (CDS)

Coding sequence (CDS)

Genome Context

Genome Context

Gene Ontology

Tertiary structure

Predicted Aligned Error (PAE)

Model Confidence