Protein

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Genbank accession

CAL9991846.1 [GenBank]

Protein name

tail spike protein with colonic acid degradation activity

RBP type

Evidence Phold

Probability 1,00

TSP

Evidence DepoScope

Probability 1,00

TSP

Evidence RBPdetect

Probability 0,86

TSP

Evidence RBPdetect2

Probability 0,94

Protein sequence

MFYNAMSRWSNTTIRDLHFDGSNNYPTDKSVYYGDVAINNVMIRKSGACTDVTIQDCYFTKASTSSIYVSDGDHTTSLKIINNKFNDGNYKLKTIGIYGSNNVSDAKAPRGIEVSGNVINGGGSRIHKDGRIEGFTSSTDAIHLDNCRHSIISKNIIRENSGDAIRVEQSKYIMVSDNSIYRSGSAGITVYHSSQRCSIIGNTIDGWGYTIQAYCIRSHGGKYYICREFPDATHAVLPTDPSTVSWIIECPYNLTGIDTSTILPYSSTDYYSSGSSTGILPFRGSSAISVTSSSYAVKIIGNICNGNTSKDASNKYHTASEHGYSNKHTVNSPVGVTGDSNTVSGNAFSNCQGHELYAGEYQDPINQRGKSGLQYISDDNSYSAHRGHGKNTDKYYTIHDNLSITSGGGEFTPTLTPSTSGSITLTGAYNALSWYRVGQMVTISGQIRVGSVSSPVGGVKIEGLPFTQLNLADGAERVAGVALCNNVEAATPPITQFFVSGAGNVMWISGTTGTTTRNIGDLIKSGTVIDVNFTYRTQI

Physico‐chemical properties

protein length:	539 AA
molecular weight:	57994,41740 Da
isoelectric point:	6,93177
aromaticity:	0,09091
hydropathy:	-0,34082

Domains

Domains [InterPro]

IPR012334
STR
2–233

IPR012334 IPR006626

IPR012334
STR
2–225

IPR012334 DC_1508

IPR006626
Unmapped
9–35

IPR006626 IPR039448

IPR011050
STR
10–212

IPR011050

IPR006626
Unmapped
49–71

IPR006626 IPR006626 IPR006626 IPR006626 IPR006626

CAL9991846.1

1 539

Architecture

STR

STR 2-539

Legend: ATT STR RBD CBM LEC ENZ CHP LNK TAS TTP UNK Unmapped

Domains [InterPro]

Domain ID	Category	Cluster	Start	End	Layer	Name	Pref Zone	Confidence	Evidence	Support
IPR012334	STR	IPR012334	2	233	Merged direct domain	Pectin lyase fold	Central	Low	Positional only	867 proteins / 867 hits
IPR012334	STR	IPR012334	2	225	Merged direct domain	Pectin lyase fold	Central	Low	Positional only	867 proteins / 867 hits
IPR006626	Unmapped	-	9	35	InterPro	Parallel beta-helix repeat	-	-	-	-
IPR011050	STR	IPR011050	10	212	Merged direct domain	Pectin lyase fold/virulence factor	Central	Low	Positional only	572 proteins / 572 hits
IPR039448	ENZ	DC_0799	46	213	InterPro cluster	Right handed beta helix domain	C-terminal	High	Text match	178 proteins / 183 hits
IPR006626	Unmapped	-	49	71	InterPro	Parallel beta-helix repeat	-	-	-	-
IPR006626	Unmapped	-	109	146	InterPro	Parallel beta-helix repeat	-	-	-	-
IPR006626	Unmapped	-	147	169	InterPro	Parallel beta-helix repeat	-	-	-	-
IPR006626	Unmapped	-	170	192	InterPro	Parallel beta-helix repeat	-	-	-	-
IPR006626	Unmapped	-	194	220	InterPro	Parallel beta-helix repeat	-	-	-	-
DC_1508	STR	DC_1508	225	539	Novel HMM	DC_1508	Central	Low	Positional only	5 proteins / 5 hits
IPR006626	Unmapped	-	338	377	InterPro	Parallel beta-helix repeat	-	-	-	-

Tail Spike Domain Segmentation

This protein has been segmented into three structural domains: N-terminal, central domain, and C-terminal.

Domain Layout

N-terminal

Central

C-terminal

CAL9991846.1

1 539

Domain	Start	End	Length (AA)	Confidence
N-terminal	1	10	10	0,0044
Central domain	11	210	201	0,9963
C-terminal	211	539	328	0,5945

Note: Constraints were applied during segmentation.
Sequence started with non-N-terminal domain|N-terminal too short, forced to 10 residues

Legend: N-terminal Central domain C-terminal

3D Structure with Domain Coloring

The structure is colored according to the domain segmentation: N-terminal (blue), Central (green), C-terminal (pink).

Domain Coloring

N-terminal
1-10

Central
11-210

C-terminal
211-539

Taxonomy

	Name	Taxonomy ID	Lineage
Phage	Vibrio phage K474 [NCBI]	3105742	Viruses > unclassified bacterial viruses >
Host	No host information

Coding sequence (CDS)

Genbank protein accession

CAL9991846.1 [NCBI]

Genbank nucleotide accession

OZ195913.1 [NCBI]

CDS location

range 87001 -> 88620
strand -

CDS

ATGTTCTATAATGCCATGTCTCGTTGGTCGAATACTACAATTCGAGACTTACATTTTGATGGTAGTAATAATTACCCTACCGACAAAAGCGTATATTACGGCGACGTGGCCATAAACAATGTTATGATTCGAAAATCTGGAGCGTGTACAGATGTTACTATCCAAGACTGCTATTTCACAAAGGCGTCAACTAGTAGCATTTATGTATCGGACGGTGACCACACCACTAGTTTGAAAATCATCAATAACAAATTCAATGACGGTAACTATAAACTGAAAACTATAGGAATTTATGGTTCTAACAACGTGTCTGACGCTAAAGCCCCTCGCGGTATTGAGGTTAGTGGTAATGTTATCAATGGAGGCGGGTCACGAATACACAAAGACGGGCGTATTGAGGGGTTCACTTCGTCAACTGATGCTATCCACTTAGACAACTGTAGACATTCAATAATCAGTAAGAATATCATTCGTGAGAATAGCGGTGATGCAATTCGGGTTGAACAATCGAAGTATATCATGGTATCTGACAATAGCATTTACCGTTCTGGTTCTGCTGGTATCACAGTGTACCATTCATCACAACGTTGTTCTATTATAGGAAACACTATCGATGGTTGGGGTTACACTATCCAAGCGTATTGTATCCGATCGCACGGCGGGAAGTATTACATATGTCGAGAGTTCCCCGACGCAACTCACGCAGTATTACCTACTGACCCTAGTACTGTGTCTTGGATTATAGAGTGCCCATACAACCTCACAGGGATTGATACGTCGACTATTTTACCTTATAGTTCTACTGATTATTACTCTAGCGGTTCGTCCACTGGTATCCTCCCGTTCCGAGGGTCAAGTGCTATATCAGTAACAAGTTCATCTTACGCAGTGAAAATTATAGGTAATATATGTAATGGTAACACGAGCAAAGATGCTAGTAATAAGTACCACACCGCGAGCGAACATGGATACTCAAATAAACATACAGTGAATAGTCCGGTTGGCGTTACAGGTGATTCGAATACTGTGTCAGGTAATGCGTTTTCTAATTGTCAAGGGCATGAACTATACGCGGGTGAATATCAAGACCCCATAAACCAACGCGGGAAATCAGGCTTGCAATATATCAGTGATGATAATTCATACAGCGCACATCGCGGCCATGGTAAGAATACTGACAAATATTATACGATTCATGACAACTTATCAATAACATCAGGCGGGGGTGAGTTCACCCCAACATTGACGCCGTCAACATCAGGTAGCATTACATTGACGGGGGCGTACAACGCTTTATCGTGGTATCGTGTCGGACAGATGGTGACAATATCAGGCCAAATACGCGTGGGGAGTGTTAGCTCGCCAGTAGGCGGCGTCAAGATTGAAGGTCTACCATTTACACAATTGAACCTTGCTGATGGGGCTGAACGCGTGGCGGGTGTGGCGTTATGCAATAATGTAGAAGCGGCCACGCCGCCTATCACCCAATTCTTTGTATCGGGAGCGGGTAATGTTATGTGGATATCAGGAACAACAGGAACAACAACACGCAACATCGGCGATTTGATAAAATCTGGAACCGTCATCGATGTGAACTTCACATATCGTACACAGATATAA

Genome Context

Tertiary structure

PDB ID

6c1efb1f218c67215fa7ffd3080a4a8c19ab072b61c5d8b295d2967ccba24d73

ESMFold

Source ESMFold

Method ESMFold

Resolution 0,6995

Oligomeric State monomer

Download PDB

Model Confidence

Very high
pLDDT > 90

High
90 > pLDDT > 70

Low
70 > pLDDT > 50

Very low
pLDDT < 50

Protein

Domains

Domains [InterPro]

Domains [InterPro]

Tail Spike Domain Segmentation

Tail Spike Domain Segmentation

3D Structure with Domain Coloring

Domain Coloring

Taxonomy

Coding sequence (CDS)

Coding sequence (CDS)

Genome Context

Genome Context

Tertiary structure

Predicted Aligned Error (PAE)

Model Confidence