Protein

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Genbank accession

QEG05462.1 [GenBank]

Protein name

tail sheath protein

RBP type

TSP

Evidence DepoScope

Probability 1,00

Protein sequence

MTLLSPGFETKETTLSTTIVQSATGRAALVGKFQWGPAFQIVQVTNEVELVNKFGQPDNNTADYFMSGANFLQYGNDLRVVRVLNTEKAKNSTTLAGNVAFEITNEGSNYKVGDVIKVKYKNSEIETGGKVTKVSTEGKVKGIFIPTGKLIAHAKAVGTYPEVNGYTVEITSGTGNSSASITISSIVTDSGLLLTDLETSRSNITNQTFLTKLKKYDMPAVSAIYAGEIGNSLEVEILSRSAFTGTAPNLTMYPYGGERTAARNLVAYGPQNDNQYAFIVRRDGVMVESFVLSTVKGDKDVYGNSIYMDDFFARGASQYIYATAQGWVDGFSGIISLAGGLSANEASTNDHQNDPFIGAMMQGWDLFAERETIHVNLLIAGACAGEGDNFSTVQKYAVSIGDERQDCLVMVSPPRSTVVNIPVTTAIDNLIHWREGSNNYSDNNMNINTTYAVIDGNYKYQYDKYNDVNRWVPLAADIAGLCARTDAVSQPWMSPAGYNRGQIMNVVKLAIEPRKAHRDRLYQAAINPVIGAGGEGFILMGDKTATTVPSPFDRINVRRLFNMLKKNIGDSSKYKLFENNDNFTRASFRMEVSQYLSTIRSLGGIYDFRVQCDTTNNTPDVIDRNEFVASMFIKPAKSINYIMLNFTAVATGADFDEIIGPANQA

Physico‐chemical properties

protein length:	665 AA
molecular weight:	72668,90560 Da
isoelectric point:	5,45225
aromaticity:	0,09624
hydropathy:	-0,21624

Domains

Domains [InterPro]

IPR052042
Unmapped
4–652

IPR052042

IPR054564
TAS
24–83

IPR054564 IPR054565 DC_1554 G3DSA:3.40.50.11780 IPR020287

G3DSA:2.40.10.380
ATT
98–187

G3DSA:2.40.10.380 IPR035326 IPR035089

QEG05462.1

1 665

Architecture

TAS

ATT

STR

TAS

TAS 24-83 | ATT 97-187 | STR 188-513 | TAS 514-545 | TAS 548-647 |

Legend: ATT STR RBD CBM LEC ENZ CHP LNK TAS TTP UNK Unmapped

Domains [InterPro]

Domain ID	Category	Cluster	Start	End	Layer	Name	Pref Zone	Confidence	Evidence	Support
IPR052042	Unmapped	-	4	652	InterPro	Tail sheath structural protein	-	-	-	-
IPR054564	TAS	DC_0229	24	83	InterPro cluster	Tail sheath protein Gp18-like, domain III N-terminal region	N-terminal	High	Text match	16 proteins / 16 hits
IPR054565	TAS	DC_0242	97	187	InterPro cluster	Tail sheath protein Gp18-like, domain I	N-terminal	High	Text match	12 proteins / 12 hits
G3DSA:2.40.10.380	ATT	G3DSA:2.40.10.380	98	187	Merged direct domain	G3DSA:2.40.10.380	N-terminal	Low	Positional only	11 proteins / 11 hits
DC_1554	STR	DC_1554	187	329	Novel HMM	DC_1554	Central	Low	Positional only	15 proteins / 15 hits
IPR035326	TAS	DC_0530	220	341	InterPro cluster	Phage tail sheath protein-like, beta-sandwich domain	Central	High	Text match	3 proteins / 3 hits
G3DSA:3.40.50.11780	STR	G3DSA:3.40.50.11780	335	513	Merged direct domain	G3DSA:3.40.50.11780	Central	Low	Positional only	39 proteins / 39 hits
IPR035089	TAS	DC_0885	367	545	InterPro cluster	Tail sheath protein, subtilisin-like domain	Central	High	Text match	30 proteins / 30 hits
IPR020287	TAS	DC_0666	548	647	InterPro cluster	Tail sheath protein, C-terminal domain	C-terminal	High	Text match	43 proteins / 43 hits

Tail Spike Domain Segmentation

This protein has been segmented into three structural domains: N-terminal, central domain, and C-terminal.

Domain Layout

N-terminal

Central

C-terminal

QEG05462.1

1 665

Domain	Start	End	Length (AA)	Confidence
N-terminal	1	111	111	0,9062
Central domain	112	310	200	0,3671
C-terminal	311	665	354	0,2179

Legend: N-terminal Central domain C-terminal

3D Structure with Domain Coloring

The structure is colored according to the domain segmentation: N-terminal (blue), Central (green), C-terminal (pink).

Domain Coloring

N-terminal
1-111

Central
112-310

C-terminal
311-665

Taxonomy

	Name	Taxonomy ID	Lineage
Phage	Shigella phage JK32 [NCBI]	2591059	Viruses > Duplodnaviria > Heunggongvirae > Uroviricota > Caudoviricetes
Host	No host information

Coding sequence (CDS)

Genbank protein accession

QEG05462.1 [NCBI]

Genbank nucleotide accession

MK962753 [NCBI]

CDS location

range 93222 -> 95219
strand +

CDS

ATGACTCTATTATCACCGGGTTTCGAAACGAAAGAAACTACTCTCTCCACTACCATTGTGCAATCTGCGACTGGTCGCGCGGCACTGGTGGGTAAATTCCAATGGGGTCCAGCTTTCCAGATTGTTCAAGTAACTAATGAAGTTGAATTAGTTAATAAATTTGGTCAGCCGGATAATAACACCGCAGACTATTTCATGAGCGGGGCTAACTTCCTCCAGTATGGCAATGATCTGCGTGTTGTTCGTGTATTGAATACAGAAAAAGCGAAAAACTCCACCACTCTCGCGGGTAACGTTGCATTTGAAATTACCAACGAAGGTTCCAACTATAAAGTTGGTGACGTAATTAAAGTAAAATATAAAAACTCAGAAATTGAAACAGGCGGTAAAGTTACTAAAGTAAGCACCGAAGGTAAAGTTAAGGGAATCTTTATTCCGACTGGTAAGCTGATCGCACACGCTAAAGCTGTTGGTACTTACCCAGAAGTAAACGGATATACCGTAGAAATCACTTCCGGTACGGGTAACTCTTCGGCATCTATTACTATTTCCAGCATTGTGACAGATTCCGGCTTGCTGTTAACCGACCTAGAAACTTCTCGCTCTAATATCACTAATCAGACTTTCTTGACCAAGCTGAAAAAATATGATATGCCAGCGGTGAGCGCAATCTATGCAGGTGAGATCGGAAACTCTCTGGAAGTTGAAATCCTTTCCCGTAGTGCATTTACTGGAACTGCTCCGAATCTGACCATGTATCCTTACGGTGGCGAACGTACCGCTGCACGCAATCTGGTGGCATACGGTCCGCAGAATGATAACCAGTACGCATTTATTGTACGTCGTGATGGCGTTATGGTAGAATCCTTTGTACTATCCACCGTAAAAGGTGATAAGGATGTTTACGGCAATTCCATTTATATGGATGATTTCTTTGCTCGTGGCGCAAGTCAGTACATCTACGCAACCGCTCAAGGCTGGGTGGATGGGTTTAGTGGCATCATCTCTCTTGCGGGTGGTCTGTCTGCTAATGAAGCATCCACCAACGACCATCAAAATGACCCGTTTATCGGTGCGATGATGCAAGGTTGGGATTTGTTCGCTGAACGTGAAACTATCCACGTAAACCTGCTTATTGCGGGTGCTTGCGCTGGTGAAGGTGATAACTTCTCTACCGTACAGAAATATGCTGTTTCCATCGGTGATGAGCGTCAGGATTGCTTAGTGATGGTTTCTCCGCCACGTAGCACCGTTGTTAATATTCCGGTCACTACCGCAATTGATAACCTGATCCACTGGCGCGAAGGTAGCAACAACTACTCAGACAACAACATGAACATTAATACCACTTACGCGGTTATTGATGGTAACTACAAATATCAGTATGACAAATATAACGATGTAAACCGTTGGGTTCCGTTGGCTGCTGATATTGCTGGCTTGTGTGCTCGTACTGATGCTGTATCCCAGCCGTGGATGAGTCCGGCAGGTTATAACCGTGGTCAGATCATGAACGTGGTTAAACTGGCAATTGAGCCTCGCAAGGCGCACCGTGACCGTCTGTATCAGGCCGCAATTAACCCGGTAATCGGTGCTGGTGGTGAAGGTTTTATCCTGATGGGTGATAAAACCGCTACGACTGTTCCTAGCCCGTTTGACCGAATTAACGTTCGTCGTCTGTTTAACATGCTGAAAAAGAATATCGGTGATTCAAGCAAATACAAACTGTTTGAAAACAATGATAACTTTACTCGCGCTTCCTTCCGTATGGAGGTTTCGCAATATCTCAGCACGATTCGCTCTCTGGGTGGCATTTATGACTTCCGAGTACAATGCGACACCACAAATAACACGCCAGATGTAATTGATCGTAACGAATTTGTTGCTAGCATGTTCATCAAACCAGCAAAATCGATCAACTATATCATGCTCAATTTCACTGCTGTTGCAACTGGTGCTGATTTTGACGAAATTATCGGTCCGGCTAACCAGGCATAA

Genome Context

Tertiary structure

PDB ID

1d113ae36f8e5fcfb5efe18db2937123a879dc2b63cdd5b15643843aff7ad482

ESMFold

Source ESMFold

Method ESMFold

Resolution 0,7745

Oligomeric State monomer

Download PDB

Model Confidence

Very high
pLDDT > 90

High
90 > pLDDT > 70

Low
70 > pLDDT > 50

Very low
pLDDT < 50

Literature

Title	Authors	Date	PMID	Source
A quest of great importance - developing a broad spectrum Shigella ssp. and Escherichia coli phage collection	Kaczorowska,J., Casey,E., Neve,H., Noben,J.-P., Lugli,G.A., Ventura,M., van Sinderen,D. and Mahony,J.	2019-09-26	—	GenBank

Protein

Domains

Domains [InterPro]

Domains [InterPro]

Tail Spike Domain Segmentation

Tail Spike Domain Segmentation

3D Structure with Domain Coloring

Domain Coloring

Taxonomy

Coding sequence (CDS)

Coding sequence (CDS)

Genome Context

Genome Context

Tertiary structure

Predicted Aligned Error (PAE)

Model Confidence

Literature