Protein

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Genbank accession
QBX29484.1 [GenBank]
Protein name
hyaluronate lyase
RBP type
TSP
Evidence DepoScope
Probability 1,00
TSP
Evidence RBPdetect2
Probability 0,96
Protein sequence
MTENIPLRVQFKRMSADEWARSDVILLEGEIGFETDTGYAKFGNGKSKFSALKYLTGPKGPKGDTGFQGKTGGTGPRGPAGKPGTTDYNQLQNKPNLDAFARKQETDSKITELKSNKADKNAVYLKAESNAKLDEKLSLTGGIVTGQLQFKPNSGIKPSSSVGGAINIDMSKSEGAAMVMYTNKDTTDGPLMILRSDKDTFDQSAQFVDYSGKTNAVNIVMRQPSAPNFSSALNITSANEGGSAMQIRGVEKALGTLKITHENPNVKANYDENAAALSIDIVKKTNGEGTAAQGIYINSTSGTTGKLLRIRNLSDDKFYVKSDGGFYAKETSQIDGNLKLKDPTANDHAATKAYVDKAISELKKLILKK
Physico‐chemical
properties
protein length:369 AA
molecular weight: 39589,08670 Da
isoelectric point:9,25890
aromaticity:0,06504
hydropathy:-0,60461

Domains

Domains [InterPro]
SSF69349
STR
7–367
SSF69349
IPR041352
ATT
9–47
IPR041352 G3DSA:1.20.5.320 IPR009860
QBX29484.1
1 369
Architecture
ATT
STR
ATT 7-47 | STR 48-367 |
Legend: ATT STR RBD CBM LEC ENZ CHP LNK TAS TTP UNK Unmapped

Tail Spike Domain Segmentation

Tail Spike Domain Segmentation

This protein has been segmented into three structural domains: N-terminal, central domain, and C-terminal.

Domain Layout
N-terminal
Central
C-terminal
QBX29484.1
1 369
Domain Start End Length (AA) Confidence
N-terminal 1 142 142 0,9855
Central domain 143 341 200 0,1824
C-terminal 342 369 27 0,9854
Legend: N-terminal Central domain C-terminal
3D Structure with Domain Coloring

The structure is colored according to the domain segmentation: N-terminal (blue), Central (green), C-terminal (pink).

Domain Coloring
N-terminal
1-142
Central
143-341
C-terminal
342-369

Taxonomy

  Name Taxonomy ID Lineage
Phage Streptococcus phage Javan498
[NCBI] 		2548212 Viruses > Duplodnaviria > Heunggongvirae > Uroviricota > Caudoviricetes
Host Streptococcus pyogenes MGAS10394
[NCBI] 		286636 Bacillota > Bacilli > Lactobacillales > Streptococcaceae > Streptococcus > Streptococcus pyogenes

Coding sequence (CDS)

Coding sequence (CDS)
Genbank protein accession
QBX29484.1 [NCBI]
Genbank nucleotide accession
MK448963 [NCBI]
CDS location
range 22705 -> 23814
strand +
CDS
ATGACTGAAAATATACCATTAAGAGTCCAATTTAAGCGCATGAGCGCTGATGAGTGGGCTCGTAGTGATGTCATCTTGCTTGAGGGTGAGATAGGTTTTGAGACTGATACAGGCTATGCTAAATTTGGTAATGGGAAAAGCAAGTTTAGCGCACTCAAATACCTTACCGGACCAAAAGGTCCTAAAGGAGACACTGGTTTCCAAGGTAAAACTGGAGGAACTGGTCCTCGGGGCCCTGCTGGCAAGCCTGGAACGACAGATTATAATCAACTCCAAAATAAACCAAATCTAGATGCGTTTGCACGAAAACAAGAAACTGATAGTAAAATCACCGAATTAAAATCAAATAAAGCAGATAAAAACGCTGTTTACTTAAAAGCAGAGTCAAATGCAAAGCTAGACGAAAAATTGAGTTTGACAGGCGGCATAGTGACAGGACAACTACAGTTTAAACCTAATAGTGGTATTAAACCCTCATCTTCCGTAGGAGGAGCGATTAACATTGATATGTCTAAATCGGAAGGTGCTGCTATGGTGATGTATACAAATAAAGATACTACTGATGGACCATTGATGATTTTACGTTCTGACAAAGATACGTTTGATCAGTCAGCTCAATTTGTGGATTACAGCGGTAAGACTAATGCTGTAAATATTGTAATGCGCCAGCCAAGCGCACCTAATTTTTCCTCGGCACTTAATATAACCAGTGCCAACGAAGGCGGTAGTGCGATGCAAATTAGAGGCGTCGAAAAAGCGCTAGGAACGCTAAAAATTACTCACGAAAACCCAAACGTTAAGGCAAATTACGATGAAAACGCTGCAGCGTTATCCATTGATATTGTCAAAAAGACAAACGGTGAAGGAACAGCCGCTCAGGGAATCTACATTAACTCAACCTCAGGCACGACAGGGAAGTTGCTTAGGATTAGAAACCTTAGTGATGATAAGTTCTACGTCAAGTCTGACGGTGGTTTTTATGCCAAGGAAACTTCGCAGATTGATGGCAACCTGAAACTCAAGGACCCCACAGCGAATGATCATGCGGCAACCAAAGCTTATGTAGATAAAGCAATTTCTGAGTTAAAAAAACTCATACTAAAAAAATAG

Genome Context

Genome Context

Tertiary structure

PDB ID
7e7cc403b76d3fa4c060a22bcc599cf796d4e35ef3a7c2fa99799fa935ae8f00
ESMFold
Source ESMFold
Method ESMFold
Resolution 0,7591
Oligomeric State monomer
Download PDB
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50

Literature

Title Authors Date PMID Source
Prophages and satellite prophages are widespread among Streptococcus species and may play a role in pneumococcal pathogenesis Rezaei Javan,R., Ramos-Sevillano,E., Akter,A., Brown,J. and Brueggemann,A.B. 2018-12-20 — GenBank