Protein

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Genbank accession
UJD04937.1 [GenBank]
Protein name
tail spike protein
RBP type
TF
Evidence Phold
Probability 1,00
TSP
Evidence DepoScope
Probability 1,00
TSP
Evidence RBPdetect
Probability 0,91
TSP
Evidence RBPdetect2
Probability 0,95
Protein sequence
MKTQFNQPQGSTSRETNKEAIARIFGIKKSEVGYLSTSTPIDSYVILFDKETQTCWYRGTATGTPVSWTVTNKLLNLTTSNGSYVLVRGYSGDILRQDLASEGMGDALVAHSGGGMVSDYIHYLTPQSQGAPCNGTDDDSSWFNDLVNSGKKVKVPAGNYVLDCNKINITTSDSEIEFDKNANVTVINTSGLSGANVEAAVFKLSGSAVAPITNFKISGGKFSYANDTICLVGVLSYVDGVLVEGVEVTGLRLISTNDANNVYANSTSASRSKRIKASFCKATAATVSTKGAAISFRYSDYGTTSNNIIYGYYYGIMFWGGDSNTGSNGGLGNERKCVGIRSTADRISATKAAWWGSMGLDCVATALSCYGIGTDTDVGIDFEGCVRCSAVGCYVKDFRYGCYATFFYSDGVVFDGCHAEVTTEGYRVFTINNSSQNANNRSVTYSNCMFSGVGCCSIVYQQGAVSDLTISNCTFRNVVLHLDSLNNGRIGINSLNMVYDRVPVDGREFNSVTYYAALVVNASALALRDCVINSSVSWTGVAGESVGVIMMSRNSNSNALHRIDGGGITSAQFSTDVIFANMGTNNGITLRYEVDKFIFANKTYKTLLFSTSTLMPIGLMRGKTVTFSDFPTSITDNLGYADTYYTRRQQFINQSPTAGGTAGSIVVTAGVGTAAVVAGLPVSSS
Physico‐chemical
properties
protein length:685 AA
molecular weight: 73014,87550 Da
isoelectric point:6,26283
aromaticity:0,09927
hydropathy:-0,03431

Domains

Domains [InterPro]
G3DSA:3.30.2020.50
ATT
1–90
G3DSA:3.30.2020.50 IPR012334 DC_2043
G3DSA:3.30.2020.50
ATT
1–95
G3DSA:3.30.2020.50 IPR011050
IPR011050
STR
124–483
IPR011050
UJD04937.1
1 685
Architecture
ATT
STR
RBD
ATT 1-95 | STR 118-483 | RBD 484-685
Legend: ATT STR RBD CBM LEC ENZ CHP LNK TAS TTP UNK Unmapped

Tail Spike Domain Segmentation

Tail Spike Domain Segmentation

This protein has been segmented into three structural domains: N-terminal, central domain, and C-terminal.

Domain Layout
N-terminal
Central
C-terminal
UJD04937.1
1 685
Domain Start End Length (AA) Confidence
N-terminal 1 131 131 0,9822
Central domain 132 624 494 0,9742
C-terminal 625 685 60 0,9487
Legend: N-terminal Central domain C-terminal
3D Structure with Domain Coloring

The structure is colored according to the domain segmentation: N-terminal (blue), Central (green), C-terminal (pink).

Domain Coloring
N-terminal
1-131
Central
132-624
C-terminal
625-685

Taxonomy

  Name Taxonomy ID Lineage
Phage Klebsiella phage PWKp5
[NCBI] 		2863273 Viruses > Duplodnaviria > Heunggongvirae > Uroviricota > Caudoviricetes
Host Klebsiella pneumoniae
[NCBI] 		573 cellular organisms > Bacteria > Pseudomonadati > Pseudomonadota > Gammaproteobacteria > Enterobacterales

Coding sequence (CDS)

Coding sequence (CDS)
Genbank protein accession
UJD04937.1 [NCBI]
Genbank nucleotide accession
MZ634341.1 [NCBI]
CDS location
range 144034 -> 146091
strand +
CDS
ATGAAAACGCAGTTCAACCAACCCCAAGGCTCCACTTCACGTGAGACTAACAAAGAAGCGATTGCTCGCATCTTTGGTATCAAGAAGTCAGAAGTCGGATATTTGTCAACGTCCACACCAATTGATTCGTATGTCATACTGTTTGACAAAGAAACTCAGACGTGTTGGTATCGAGGCACAGCGACTGGAACTCCTGTCAGCTGGACTGTAACAAATAAATTGTTGAACTTAACAACTTCTAACGGTTCATATGTTCTTGTAAGAGGATATTCTGGTGACATTCTTCGTCAAGACCTGGCTTCAGAAGGCATGGGTGATGCATTGGTTGCACATTCCGGTGGGGGTATGGTTAGTGATTATATCCACTATTTAACACCCCAGTCTCAAGGAGCACCCTGCAATGGGACTGACGACGATTCGTCGTGGTTTAACGATCTAGTCAACAGTGGAAAAAAAGTTAAAGTTCCAGCAGGTAACTATGTTCTGGACTGTAATAAAATAAACATTACCACGTCTGATTCTGAGATTGAGTTCGATAAAAATGCTAATGTTACCGTCATCAATACCTCTGGTTTGTCTGGAGCTAATGTAGAAGCAGCTGTTTTTAAACTATCAGGTTCAGCAGTAGCACCGATAACCAACTTTAAAATCAGCGGCGGTAAGTTCTCCTATGCCAATGACACCATTTGTCTCGTCGGGGTATTGTCATATGTAGATGGAGTGTTGGTTGAAGGCGTGGAGGTTACTGGCCTTCGTCTCATCTCAACAAATGACGCAAACAACGTTTATGCTAATAGCACTAGCGCCAGCCGGTCTAAACGCATTAAGGCGTCTTTCTGCAAGGCAACTGCCGCAACCGTATCAACGAAGGGGGCCGCAATTAGCTTTCGTTATTCTGACTATGGTACAACATCCAATAACATTATCTATGGGTATTACTACGGAATCATGTTTTGGGGTGGCGACTCCAATACGGGCAGTAACGGCGGCTTGGGGAACGAGAGAAAGTGTGTTGGAATAAGGTCTACTGCTGACAGAATCTCTGCCACTAAAGCAGCGTGGTGGGGGTCAATGGGCTTGGATTGCGTTGCAACGGCACTGAGCTGCTACGGCATTGGGACGGATACGGATGTTGGGATAGACTTTGAAGGGTGCGTGAGATGCTCTGCCGTAGGGTGTTATGTTAAAGATTTTCGCTATGGGTGCTATGCTACCTTCTTTTATAGCGATGGCGTAGTGTTTGATGGTTGTCATGCTGAAGTCACAACAGAAGGTTACAGGGTATTCACTATCAACAACTCAAGCCAGAACGCTAACAATCGAAGTGTGACTTACAGCAATTGTATGTTCAGCGGGGTTGGGTGCTGCTCTATTGTATATCAGCAGGGTGCTGTAAGTGATTTGACAATCAGTAACTGCACGTTCAGGAATGTAGTGCTGCATCTGGATTCTTTGAACAACGGTCGTATTGGAATCAATAGCCTTAATATGGTTTATGACCGAGTACCTGTTGATGGCCGTGAATTTAACTCTGTAACGTACTACGCTGCTCTGGTTGTAAATGCATCGGCATTGGCTCTGCGTGATTGCGTCATAAATTCATCAGTATCCTGGACTGGAGTAGCGGGGGAGTCTGTTGGGGTTATTATGATGTCTCGCAATTCGAATAGCAACGCACTCCATCGAATTGATGGTGGTGGTATTACCTCTGCTCAATTTAGTACTGATGTAATTTTTGCTAATATGGGCACGAATAATGGGATTACTTTGCGGTATGAAGTAGATAAGTTTATTTTTGCCAACAAAACTTATAAAACACTATTATTCAGCACATCCACACTTATGCCAATTGGGTTAATGCGTGGTAAAACAGTAACTTTTTCAGACTTTCCAACATCCATAACTGATAATCTAGGGTATGCCGACACTTACTACACACGTAGGCAGCAGTTTATTAACCAGTCTCCAACTGCTGGTGGTACTGCTGGTTCTATTGTTGTTACGGCAGGTGTTGGTACGGCAGCTGTGGTTGCCGGGTTGCCTGTATCGTCATCTTAA

Genome Context

Genome Context

Tertiary structure

PDB ID
650ab12615c516038485e457c447275c7582d5d9c95c9b1ab49fd8804dca298d
ESMFold
Source ESMFold
Method ESMFold
Resolution 0,7379
Oligomeric State monomer
Download PDB
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50

Literature

Title Authors Date PMID Source
Lytic Bacteriophages against Mutidrug-Resistant Klebsiella pneumoniae: Development of an Effective Phage-based Approach to Combat Multidrug Resistance Martins,W.M.B.S., Cino,J., Lenzi,M.H., Sands,K., Portal,E., Mathias,J., Hansan,B., Dantas,P., Migliavacca,R., Hunter,J.R., Medeiros,E.A., Gales,A.C. and Toleman,M.A. 2021 — GenBank