Protein
- UniProt accession
- Q6QGK2 [UniProt]
- Protein name
- Tail fiber protein
- RBP type
-
TFTFTF
- Protein sequence
-
MTTRISKTRALATIKSLEAKIRKATEQQLLIAVGEGKDKNQVVVGAAIEVDALSTRIKTDFQSLLDMMSQRDRIKAALIKSNAETIVEIGSRKMTVAEAIEAKRSMELKAQLLANMRKQFHAATVKFNTQKAQFDAKYERLQDSMATRDKKTSEDEVKMQLNLLELKNTPFLIDPLGLEKLIKQHDEEYQDFATNVDFVLSESNASTFIEVE
- Physico‐chemical
properties -
protein length: 212 AA molecular weight: 23925,26850 Da isoelectric point: 7,83795 aromaticity: 0,04717 hydropathy: -0,39811
Domains
Domains [InterPro]
Coil
7–27
7–27
1
212
Legend:
Pfam
SMART
CDD
TIGRFAM
HAMAP
SUPFAM
PRINTS
Gene3D
PANTHER
Other
Taxonomy
| Name | Taxonomy ID | Lineage | |
|---|---|---|---|
| Phage |
Escherichia phage T5 [NCBI] |
2695836 | Viruses > Duplodnaviria > Heunggongvirae > Uroviricota > Caudoviricetes |
| Host | No host information | ||
Coding sequence (CDS)
Coding sequence (CDS)
No CDS data available.
Gene Ontology
No Gene Ontology terms available.
Enzymatic activity
No enzymatic activity data available.
Tertiary structure
PDB ID
8fd0879c053e67906372d091f5e798ac90dc68e0d6c752eb8d6948ed100052a6
Literature
| Title | Authors | Date | PMID | Source |
|---|---|---|---|---|
| Location of genes D16, D17, and N4 encoding tail proteins on the physical map of bacteriophage T5. | Krauel V, Heller KJ | 1987 | 2958389 | PubMed |
| Bacteriophage-induced ribonucleotide reductase systems. T5- and T6-specific ribonucleotide reductase and thioredoxin. | Eriksson S, Berglund O | 1974-07-15 | 4152788 | PubMed |
| Isolation and characterization of a bacteriophage T5 mutant deficient in deoxynucleoside 5'-monophosphatase activity. | Mozer TJ, Thompson RB, Berget SM, Warner HR | 1977-11 | 335083 | PubMed |
| Mechanism of T5-induced DNA polymerase. I. Replication of short primer templates. | Das SK, Fujimura RK | 1977-12-10 | 336621 | PubMed |
| [Features of the structure of transfer RNA coded by bacteriophage T5]. | Shliapnikov MG, Ksenzenko VN | 1994-11 | 7533890 | PubMed |
| Interaction of a DNA-binding protein, the gene product of D5 of bacteriophage T5, with double-stranded DNA. Analysis by metrizamide gradient centrifugation. | Fujimura RK, Roop BC | 1982-12-25 | 6294081 | PubMed |
| Cloning and overexpression of the gene encoding bacteriophage T5 DNA polymerase. | Chatterjee DK, Fujimura RK, Campbell JH, Gerard GF | 1991-01-02 | 1995424 | PubMed |
| The structural gene for deoxyribonucleic acid polymerase in bacteriophages T4 and T5. | De Waard A, Paul AV, Lehman IR | 1965-10 | 5219829 | PubMed |
| Identification by immunobinding assay of the polypeptide coded by the DNA polymerase gene of bacteriophage T5 and its amber mutants and the direction of transcription of the gene. | Schneider SS, Roop BC, Fujimura RK | 1985-10 | 3897573 | PubMed |
| Mechanism of T5-induced DNA polymerase. II. Characterization of the dead-end complex. | Das SK, Fujimura RK | 1977-12-10 | 411791 | PubMed |
| Purification and characterization of the deoxynucleoside monophosphate kinase of bacteriophage T5. | Mikoulinskaia GV, Gubanov SI, Zimin AA, Kolesnikov IV, Feofanov SA, Miroshnikov AI | 2003-02 | 12597877 | PubMed |
| Identification of the gene controlling the synthesis of the major bacteriophage T5 membrane protein. | Duckworth DH, Dunn GB, McCorquodale DJ | 1976-05 | 775127 | PubMed |
| Structure-specific DNA binding by bacteriophage T5 5'-->3' exonuclease. | Garforth SJ, Sayers JR | 1997-10-01 | 9380501 | PubMed |
| The deoxyribonuclease induced after infection of Escherichia coli by bacteriophage T5. I. Characterization of the enzyme as a 5'-exonuclease. | Frenkel GD, Richardson CC | 1971-08-10 | 4327330 | PubMed |
| Isolation and partial characterization of a bacteriophage T5 mutant unable to induce thymidylate synthetase and its use in studying the effect of uracil incorporation into DNA on early gene expression. | Swart WJ Jr, Warner HR | 1985-04 | 3973984 | PubMed |
| An intramolecular disulphide bond reduces the efficacy of a lipoprotein plasma membrane sorting signal. | Robichon C, Bonhivers M, Pugsley AP | 2003-08 | 12890035 | PubMed |
| Properties of deoxynucleoside 5'-monophosphatase induced by bacteriophage T5 after infection of Escherichia coli. | Mozer TJ, Warner HR | 1977-11 | 21305 | PubMed |
| Identification of the phage gene for host receptor specificity by analyzing hybrid phages of T5 and BF23. | Heller KJ | 1984-11 | 6093378 | PubMed |
| Unusually wide co-factor tolerance in a metalloenzyme; divalent metal ions modulate endo-exonuclease activity in T5 exonuclease. | Garforth SJ, Patel D, Feng M, Sayers JR | 2001-07-01 | 11433022 | PubMed |
| Structural proteins of bacteriophage T5. | Zweig M, Cummings DJ | 1973-02 | 4571380 | PubMed |
| Pre-early polypeptides of bacteriophages T5 and BF23. | McCorquodale DJ, Shaw AR, Shaw PK, Chinnadurai G | 1977-05 | 325230 | PubMed |
| A helical arch allowing single-stranded DNA to thread through T5 5'-exonuclease. | Ceska TA, Sayers JR, Stier G, Suck D | 1996-07-04 | 8657312 | PubMed |
| The nucleotide sequence of bacteriophage T5 leucine tRNA. | Shlyapnikov MG, Kazantsev SI, Kryukov VM, Bayev AA | 1985-11-18 | 3905432 | PubMed |
| THE ENZYMOLOGY OF VIRUS-INFECTED BACTERIA. VI. PURIFICATION AND PROPERTIES OF THE DEOXYNUCLEOTIDE KINASE INDUCED BY BACTERIOPHAGE T5. | BESSMAN MJ, HERRIOTT ST, ORR MJ | 1965-01 | 14253449 | PubMed |
| Identification of the bacteriophage T5 dUTPase by protein sequence comparisons. | Kaliman AV | 1996 | 8988373 | PubMed |
| Amino acid sequence of the bacteriophage T5 gene A2 protein. | Snyder CE Jr | 1991-06-28 | 2059212 | PubMed |
| Prokaryotic 5'-3' exonucleases share a common core structure with gamma-delta resolvase. | Artymiuk PJ, Ceska TA, Suck D, Sayers JR | 1997-11-01 | 9336450 | PubMed |
| DNA filter retention assay for exonuclease activities. Application to the analysis of processivity of phage T5 induced 5'-exonuclease. | Joannes M, Saucier JM, Jacquemin-Sablon A | 1985-12-31 | 3004572 | PubMed |
| Mutagenesis of conserved lysine residues in bacteriophage T5 5'-3' exonuclease suggests separate mechanisms of endo-and exonucleolytic cleavage. | Garforth SJ, Ceska TA, Suck D, Sayers JR | 1999-01-05 | 9874768 | PubMed |
| Cloning of bacteriophage T5 DNA fragments. III. Expression in Escherichia coli mini-cells. | Brunel F, Davison J, Ha-Thi V, Reeve J | 1981-12 | 6282684 | PubMed |
| [Primary structure of tRNAAsn of bacteriophage T5]. | Shliapnikov MG, Kriukov VM, Baev AA | 1987-04 | 3649233 | PubMed |
| Cell-free transcription and translation of isolated restriction fragments localize bacteriophage T5 pre-early genes. | Blaisdell PW, Warner HR | 1986-03 | 3951019 | PubMed |
| Patterns of protein synthesis in Escherichia coli infected by amber mutants in the first-step-transfer DNA of T5. | McCorquodale DJ, Lanni YT | 1970-02-28 | 4915289 | PubMed |
| Inactivation of FhuA at the cell surface of Escherichia coli K-12 by a phage T5 lipoprotein at the periplasmic face of the outer membrane. | Braun V, Killmann H, Herrmann C | 1994-08 | 8045901 | PubMed |
| Processiveness of DNA polymerases. A comparative study using a simple procedure. | Das SK, Fujimura RK | 1979-02-25 | 368069 | PubMed |
| Electron micrographs of nicked DNA replicated by T5 DNA polymerase. | Fujimura RK, Allison DP | 1976-04-10 | 1270429 | PubMed |
| Cloning of genes for bacteriophage T5 stable RNAs. | Ksenzenko VN, Kamynina TP, Kazantsev SI, Shlyapnikov MG, Kryukov VM, Bayev AA | 1982-05-31 | 6285979 | PubMed |
| Overproduced and purified receptor binding protein pb5 of bacteriophage T5 binds to the T5 receptor protein FhuA. | Mondigler M, Vögele RT, Heller KJ | 1995-08-01 | 7649453 | PubMed |
| Identification, cloning, and expression of bacteriophage T5 dnk gene encoding a broad specificity deoxyribonucleoside monophosphate kinase (EC 2.7.4.13). | Mikoulinskaia GV, Zimin AA, Feofanov SA, Miroshnikov AI | 2004-02 | 14711503 | PubMed |
| Variation in the steady state kinetic parameters of wild type and mutant T5 5'-3'-exonuclease with pH. Protonation of Lys-83 is critical for DNA binding. | Pickering TJ, Garforth S, Sayers JR, Grasby JA | 1999-06-18 | 10364212 | PubMed |
| Mechanism of 3' to 5' exonuclease associated with phage T5-induced DNA polymerase: processiveness and template specificity. | Das SK, Fujimura RK | 1980-02-11 | 6255449 | PubMed |
| Modification of RNA polymerase from Escherichia coli by pre-early gene products of bacteriophage T5. | McCorquodale DJ, Chen CW, Joseph MK, Woychik R | 1981-12 | 7033565 | PubMed |
| Early events after infection of Escherichia coli by bacteriophage T5. Induction of a 5'-nucleotidase activity and excretion of free bases. | Warner HR, Drong RF, Berget SM | 1975-02 | 163355 | PubMed |
| Inactivation in vitro of the Escherichia coli outer membrane protein FhuA by a phage T5-encoded lipoprotein. | Pedruzzi I, Rosenbusch JP, Locher KP | 1998-11-01 | 9812372 | PubMed |
| The nucleotide sequence of bacteriophage T5 glutamine transfer RNA. | Shlyapnikov MG, Kaliman AV, Kazantsev SI, Kryukov VM, Bayev AA | 1984-07-18 | 6733112 | PubMed |
| Two early genes of bacteriophage T5 encode proteins containing an NTP-binding sequence motif and probably involved in DNA replication, recombination and repair. | Blinov VM, Koonin EV, Gorbalenya AE, Kaliman AV, Kryukov VM | 1989-07-31 | 2547651 | PubMed |
| The deoxyribonuclease induced after infection of Escherichia coli by bacteriophage T5. II. Role of the enzyme in replication of the pahge deoxyribonucleic acid. | Frenkel GD, Richardson CC | 1971-08-10 | 4934992 | PubMed |
| O antigen-dependent mutant of bacteriophage T5. | Heller KJ, Bryniok D | 1984-01 | 6361278 | PubMed |
| Nucleotide sequence of the bacteriophage T5 DNA fragment containing a distal part of tRNA gene region. | Ksenzenko VN, Shlyapnikov MG, Azbarov VG, Garcia O, Kryukov VM, Bayev AA | 1987-07-10 | 3299272 | PubMed |
| The properties of a bacteriophage T5 mutant unable to induce deoxyuridine 5'-triphosphate nucleotidohydrolase. Synthesis of uracil-containing T5 deoxyribonucleic acid. | Warner HR, Thompson RB, Mozer TJ, Duncan BK | 1979-08-25 | 381286 | PubMed |
| Cloning and DNA sequence of the genes for two bacteriophage T5 tRNAsSer. | Kryukov VM, Ksenzenko VN, Kaliman AV, Bayev AA | 1983-07-11 | 6552980 | PubMed |
| Virus-induced acquisition of metabolic function. IV. Thymidylate synthetase in thymine-requiring Escherichia coli infected by T2 and T5 bacteriophages. | BARNER HD, COHEN SS | 1959-11 | 13796860 | PubMed |
| Properties of overexpressed phage T5 D15 exonuclease. Similarities with Escherichia coli DNA polymerase I 5'-3' exonuclease. | Sayers JR, Eckstein F | 1990-10-25 | 2211703 | PubMed |
| The enzymology of virus-infected bacteria. VII. A new deoxyribonucleic acid polymerase induced by bacteriophage T5. | Orr CW, Herriott ST, Bessman MJ | 1965-12 | 5846986 | PubMed |
| [Primary structure of proline tRNA of bacteriophage T5]. | Shliapnikov MG, Kaliman AV, Kriukov VM, Baev AA | 1987-04 | 3649234 | PubMed |
| Characterization of DNA polymerase induced by bacteriophage T5 with DNA containing single strand breaks. | Fujimura RK, Roop BC | 1976-04-10 | 773933 | PubMed |
| Mechanism of primer-template-dependent conversion of dNTP leads to dNMP by T5 DNA polymerase. | Das SK, Fujimura RK | 1980-08-10 | 6248549 | PubMed |
| Early events after infection of Escherichia coli by bacteriophage T5. II. Control of the bacteriophage-induced 5'-nucleotidase activity. | Berget SM, Mozer TJ, Warner HR | 1976-04 | 176472 | PubMed |
| Exonuclease associated with bacteriophage T5-Induced DNA polymerase. | Das SK, Fujimura RK | 1976-10 | 10451 | PubMed |
| Bacteriophage T5 gene A2 protein alters the outer membrane of Escherichia coli. | Snyder CE Jr | 1984-12 | 6389511 | PubMed |
| Physical locus of the DNA polymerase gene and genetic maps of bacteriophage T5 mutants. | Fujimura RK, Tavtigian SV, Choy TL, Roop BC | 1985-02 | 2982033 | PubMed |
| Cloning and DNA sequence of the 5'-exonuclease gene of bacteriophage T5. | Kaliman AV, Krutilina AI, Kryukov VM, Bayev AA | 1986-01-20 | 3002857 | PubMed |
| Gene D5 product of bacteriophage T5: DNA-binding protein affecting DNA replication and late gene expression. | McCorquodale DJ, Gossling J, Benzinger R, Chesney R, Lawhorne L, Moyer RW | 1979-01 | 219226 | PubMed |
| The nucleotide sequence of the region of bacteriophage T5 early genes D10-D15. | Kaliman AV, Kryukov VM, Bayev AA | 1988-11-11 | 3057441 | PubMed |
| [Amber-suppressive tRNA from bacteriophage T5: construction of genes and determination of the effectiveness of suppression in vivo]. | Pan'kova NV, Karamyshev AL, Shliapnikov MG, Presich AN, Ksenzenko VN | 1998-11 | 9929878 | PubMed |
| Nucleotide sequence of the phage T5 DNA segment containing six tRNA genes. | Ksenzenko VN, Wilkens K, Rueger W, Shlyapnikov MG | 1992-11-25 | 1461745 | PubMed |
| Pre-early proteins of bacteriophage T5: structure and function. | Beckman LD, Hoffman MS, McCorquodale DJ | 1971-12-28 | 5136582 | PubMed |
| Nucleotide sequence of the bacteriophage T5 DNA fragment which contains the gene for tRNAAsp. | Shlyapnikov MG, Ksenzenko VN, Kryukov VM, Bayev AA | 1986-04-15 | 3516691 | PubMed |
| Second-step transfer of bacteriophage T5 DNA: purification and characterization of the T5 gene A2 protein. | Snyder CE Jr, Benzinger RH | 1981-10 | 7288924 | PubMed |
| Functions of two genes in the first-step-transfer DNA of bacteriophage T5. | Lanni Y | 1969-08-28 | 4897799 | PubMed |
| T5 DNA polymerase: structural--functional relationships to other DNA polymerases. | Leavitt MC, Ito J | 1989-06 | 2660138 | PubMed |
| Irreversible binding to the receptor of bacteriophages T5 and BF23 does not occur with the tip of the tail. | Heller KJ, Schwarz H | 1985-05 | 3886629 | PubMed |
| Interaction of a DNA-binding protein, the product of gene D5 of bacteriophage T5, with double-stranded DNA: effects on T5 DNA polymerase functions in vitro. | Fujimura RK, Roop BC | 1983-06 | 6304341 | PubMed |
| The purification and properties of a double-stranded DNA-binding protein encoded by the gene D5 of bacteriophage T5. | Rice AC, Ficht TA, Holladay LA, Moyer RW | 1979-08-25 | 224043 | PubMed |
| Genetic and physiological studies of bacteriophage T5. 3. Patterns of deoxyribonucleic acid synthesis induced by mutants of T5 and the identification of genes influencing the appearance of phage-induced dihydrofolate reductase and deoxyribonuclease. | Hendrickson HE, McCorquodale DJ | 1972-06 | 4556511 | PubMed |
| In vivo repair of bacteriophage t5 DNA: an assay for viral growth control. | Herman RC, Moyer RW | 1975-08 | 1098275 | PubMed |
| A single-strand specific endonuclease activity copurifies with overexpressed T5 D15 exonuclease. | Sayers JR, Eckstein F | 1991-08-11 | 1651477 | PubMed |
| Temperature-sensitive DNA polymerase induced by a bacteriophage T5 mutant: relationship between polymerase and exonuclease activities. | Fujimura RK, Roop BC | 1976-10-05 | 974066 | PubMed |
| A single cleavage assay for T5 5'-->3' exonuclease: determination of the catalytic parameters forwild-type and mutant proteins. | Pickering TJ, Garforth SJ, Thorpe SJ, Sayers JR, Grasby JA | 1999-02-01 | 9889266 | PubMed |
| Nucleotide sequence of the phage T5 DNA segment containing six tRNA genes | Vladimir N. Ksenzenko, Karl Wilken, Wolfgang Rueger, Michael G. Shlyapnikov | 1992 | 10.1093/nar/20.22.6104 | DOI |
| Mutagenesis of conserved lysine residues in bacteriophage T5 5′-3′ exonuclease suggests separate mechanisms of endoand exonucleolytic cleavage | Scott J. Garforth, Thomas A. Ceska, Dietrich Suck, Jon R. Sayers | 1999-01-05 | 10.1073/pnas.96.1.38 | DOI |
| Identification, cloning, and expression of bacteriophage T5 dnk gene encoding a broad specificity deoxyribonucleoside monophosphate kinase (EC 2.7.4.13) | Galina V Mikoulinskaia, Andrei A Zimin, Sergei A Feofanov, Anatolii I Miroshnikov | 2004-02 | 10.1016/j.pep.2003.07.006 | DOI |
| Two early genes of bacteriophage T5 encode proteins containing an NTP‐binding sequence motif and probably involved in DNA replication, recombination and repair | V.M. Blinov, E.V. Koonin, A.E. Gorbalenya, A.V. Kaliman, V.M. Kryukov | 1989-07 | 10.1016/0014-5793(89)80887-7 | DOI |
| T5 DNA polymerase: structural--functional relationships to other DNA polymerases. | M C Leavitt, J Ito | 1989-06 | 10.1073/pnas.86.12.4465 | DOI |
| Cloning and overexpression of the gene encoding bacteriophage T5 DNA polymerase | Deb K. Chatterjeea, Robert K. Fujimurab, James H. Campbella, Gary F. Gerarda | 1991-01 | 10.1016/0378-1119(91)90004-U | DOI |
| Amino acid sequence of the bacteriophage T5 gene A2 protein | Clifford E. Snyder | 1991-06 | 10.1016/0006-291X(91)90674-V | DOI |
| Structural proteins of bacteriophage T5 | Martin Zweig, Donald J. Cummings | 1973-02 | 10.1016/0042-6822(73)90443-1 | DOI |
| The nucleotide sequence of bacteriophage T5 glutamine transfer RNA | Michael G. Shlyapnikov, Alexander V. Kaliman, Sergei I. Kazantsev, Valentine M. Kryukov, A.A. Bayev | 1984-07 | 10.1016/0167-4781(84)90067-8 | DOI |
| The nucleotide sequence of the region of bacteriophage T5 early gene D10–D15 | A. V. Kaliman, V. M. Kryukov, A. A. Bayev | 1988 | 10.1093/nar/16.21.10353 | DOI |
| Nucleotide sequence of the bacteriophage T5 DNA fragment containing a distal part of tRNA gene region | V.N. Ksenzenko, M.G. Shlyapnikov, V.G. Azbarov, O. Garcia, V.M. Kryukov, A.A. Bayev | 1987 | 10.1093/nar/15.13.5480 | DOI |
| A helical arch allowing single-stranded DNA to thread through T5 5'-exonuclease | T. A. Ceska, J. R. Sayers, G. Stier, D. Suck | 1996-07 | 10.1038/382090a0 | DOI |
| Cloning and DNA sequence of the genes for two bacteriophage T5 tRNAs<sup>Ser</sup> | V.M. Kryukov, V.N. Ksenzenko, A.V. Kaliman, A.A. Bayev | 1983-07-11 | 10.1016/0014-5793(83)80690-5 | DOI |
| Cloning of genes for bacteriophage T5 stable RNAs | V.N. Ksenzenko, T.P. Kamynina, S.I. Kazantsev, M.G. Shlyapnikov, V.M. Kryukov, A.A. Bayev | 1982-05 | 10.1016/0167-4781(82)90082-3 | DOI |
| A single cleavage assay for T5 5'->3' exonuclease: Determination of the catalytic parameters for wild-type and mutant proteins | T. J. Pickering, S. J. Thorpe, J. A. Grasby, S. J. Garforth, J. R. Sayers | 1999-02-01 | 10.1093/nar/27.3.730 | DOI |
| Nucleotide sequence of the bacteriophage T5 DNA fragment which contains the gene for tRNAAsp | Michael G. SHLYAPNIKOV, Vladimir N. KSENZENKO, Valentine M. KRYUKOV, Alexander A. BAYEV | 1986-04 | 10.1111/j.1432-1033.1986.tb09579.x | DOI |
| Patterns of protein synthesis in Escherichia coli infected by amber mutants in the first-step-transfer DNA of T5 | D.J. McCorquodale, Y.T. Lanni | 1970-02 | 10.1016/0022-2836(70)90224-X | DOI |
| The nucleotide sequence of bacteriophage T 5 leucine tRNA | M.G. Shiyapnikov, S.I. Kazantsev, V.M. Kryukov, A.A. Bayev | 1985-11-18 | 10.1016/0014-5793(85)80129-0 | DOI |
| Cloning and DNA sequence of the 5'‐exonuclease gene of bacteriophage T5 | A.V. Kaliman, A.I. Krutilina, V.M. Kryukov, A.A. Bayev | 1986-01-20 | 10.1016/0014-5793(86)80130-2 | DOI |