Protein

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Genbank accession

ALY06997.1 [GenBank]

Protein name

putative terminase large subunit

RBP type

TSP

Evidence DepoScope

Probability 1,00

Protein sequence

MNDKFLEINPCNDEWEVLSTDDGWVDVLYSNKTVEYESWFLKLDNGLELNCADTHLVFTDDNTAKPVCGLKVGDSIITQFGPSKVAIIERSNLYENMYDLTVNNSKHSYLTNNIASHNTTVTAILLAHYVIFNESKAVGVLAHLGSMSREVLDRIKQAIEMLPDFLQPGIVEWNKGSIALENGSSIAAYASSPDAVRGNSFSMIYVDECVSGDTMVTVRDTTTDEILKVTIEELNKMIVKDKMIQLKGRLFENRYEILTSNGMKSFDGVKRVVSKAMRIVLDDGRELTGSYNHKVLSGNRYVSLCNLRVGSFVDGGKITHIEDCGEMSLYDALNVADGNHYTTNGIESHNCAFIENFTETWKAILPVVSSGRNSKILLTSTPNGMNHWYDLWQTAIKDNTKGFIPYSADWTSVKERLYNGADIFDDGYEWAIVQIESSTIENFRQEHMTVFVGASNTLINGFKLSKITAVDVDSPDSAFYKFEEPQENRKYVFTVDVSEGRGQDYSVIQMIDVTEYPYKQVGLYRNNRISHLLLPSVIKRYAEMYNDAYVYIELNSVGGTVAKTLYVDLEYENVICDSSIDLGMKQTKTTKQIGCSTLKDLIEKDKLIIRDKHTISELRTFVEHGKSWAAQKGFHDDCVMGLVIFAYLTTQPRFYDYIDEDRNIGIDLFEEELDELYGDFSIGLIISNADGDIDVDNQQDNAWF

Physico‐chemical properties

protein length:	704 AA
molecular weight:	79552,59070 Da
isoelectric point:	4,74011
aromaticity:	0,10085
hydropathy:	-0,26960

Domains

Domains [InterPro]

G3DSA:2.170.16.10
RBD
7–119

G3DSA:2.170.16.10 PF03237 IPR036844 PF03237 IPR035421

IPR036844
STR
11–119

IPR036844 IPR027417 IPR027417 G3DSA:3.30.420.240

cd00081
RBD
41–118

cd00081 IPR036844 G3DSA:3.30.420.240

IPR030934
RBD
96–119

IPR030934 IPR006141

IPR006141
STR
209–296

IPR006141

ALY06997.1

1 704

Architecture

STR

RBD

STR 7-465 | RBD 466-662 |

Legend: ATT STR RBD CBM LEC ENZ CHP LNK TAS TTP UNK Unmapped

Domains [InterPro]

Domain ID	Category	Cluster	Start	End	Layer	Name	Pref Zone	Confidence	Evidence	Support
G3DSA:2.170.16.10	RBD	G3DSA:2.170.16.10	7	119	Merged direct domain	G3DSA:2.170.16.10	C-terminal	Low	Positional only	27 proteins / 27 hits
IPR036844	STR	IPR036844	11	119	Merged direct domain	Hint domain superfamily	Central	Low	Positional only	8 proteins / 8 hits
cd00081	RBD	DC_0422	41	118	InterPro cluster	cd00081	C-terminal	Low	Positional only	32 proteins / 32 hits
IPR030934	RBD	DC_0392	96	119	InterPro cluster	Intein C-terminal splicing region	C-terminal	Low	Positional only	10 proteins / 10 hits
PF03237	STR	DC_0551	119	210	InterPro cluster	Terminase large subunit, T4likevirus-type, N-terminal	Central	Low	Positional only	2 proteins / 3 hits
IPR027417	STR	IPR027417	120	229	Merged direct domain	P-loop containing nucleoside triphosphate hydrolase	Central	Low	Positional only	7 proteins / 7 hits
IPR036844	STR	IPR036844	209	351	Merged direct domain	Hint domain superfamily	Central	Low	Positional only	8 proteins / 8 hits
IPR006141	STR	DC_0095	209	297	InterPro cluster	Intein N-terminal splicing region	Central	Low	Positional only	15 proteins / 16 hits
IPR006141	STR	DC_0095	209	296	InterPro cluster	Intein N-terminal splicing region	Central	Low	Positional only	15 proteins / 16 hits
IPR036844	STR	IPR036844	210	351	Merged direct domain	Hint domain superfamily	Central	Low	Positional only	8 proteins / 8 hits
IPR027417	STR	IPR027417	341	408	Merged direct domain	P-loop containing nucleoside triphosphate hydrolase	Central	Low	Positional only	7 proteins / 7 hits
PF03237	STR	DC_0551	351	465	InterPro cluster	Terminase large subunit, T4likevirus-type, N-terminal	Central	Low	Positional only	2 proteins / 3 hits
G3DSA:3.30.420.240	RBD	G3DSA:3.30.420.240	450	662	Merged direct domain	G3DSA:3.30.420.240	C-terminal	Low	Positional only	3 proteins / 3 hits
G3DSA:3.30.420.240	RBD	G3DSA:3.30.420.240	450	650	Merged direct domain	G3DSA:3.30.420.240	C-terminal	Low	Positional only	3 proteins / 3 hits
IPR035421	RBD	DC_0210	494	659	InterPro cluster	Terminase, large subunit gp17-like, C-terminal	C-terminal	Low	Positional only	2 proteins / 2 hits

Tail Spike Domain Segmentation

This protein has been segmented into three structural domains: N-terminal, central domain, and C-terminal.

Domain Layout

N-terminal

Central

C-terminal

ALY06997.1

1 704

Domain	Start	End	Length (AA)	Confidence
N-terminal	1	10	10	0,0138
Central domain	11	236	227	0,6560
C-terminal	237	704	467	0,2136

Note: Constraints were applied during segmentation.
Sequence started with non-N-terminal domain|N-terminal too short, forced to 10 residues

Legend: N-terminal Central domain C-terminal

3D Structure with Domain Coloring

The structure is colored according to the domain segmentation: N-terminal (blue), Central (green), C-terminal (pink).

Domain Coloring

N-terminal
1-10

Central
11-236

C-terminal
237-704

Taxonomy

	Name	Taxonomy ID	Lineage
Phage	Vibrio phage vB_VmeM-32 [NCBI]	1775142	Viruses > Duplodnaviria > Heunggongvirae > Uroviricota > Caudoviricetes
Host	Vibrio metschnikovii [NCBI]	28172	cellular organisms > Bacteria > Pseudomonadati > Pseudomonadota > Gammaproteobacteria > Vibrionales

Coding sequence (CDS)

Genbank protein accession

ALY06997.1 [NCBI]

Genbank nucleotide accession

KU160494 [NCBI]

CDS location

range 1102 -> 3216
strand +

CDS

ATGAATGATAAATTTTTGGAGATTAATCCATGTAACGATGAGTGGGAAGTTTTATCGACCGATGATGGATGGGTTGATGTATTGTATTCAAACAAAACTGTTGAATATGAAAGCTGGTTTTTAAAATTGGACAACGGATTGGAGTTGAATTGCGCTGATACTCACCTTGTTTTTACTGACGATAATACAGCTAAACCCGTTTGCGGTTTAAAAGTTGGTGATTCCATTATCACACAATTCGGCCCCAGTAAAGTTGCAATTATCGAACGGTCTAATCTGTACGAAAATATGTACGATTTGACTGTAAACAATAGTAAACACTCTTATTTGACTAATAACATCGCATCACATAATACGACTGTAACCGCTATTTTGTTGGCTCACTATGTGATTTTTAATGAATCTAAAGCTGTTGGTGTTTTAGCTCACTTGGGTTCGATGAGTCGCGAAGTTTTGGACCGAATAAAACAAGCTATTGAAATGTTGCCAGATTTCTTACAACCGGGAATTGTCGAATGGAACAAAGGCTCAATTGCACTAGAAAATGGTTCTAGTATTGCCGCATACGCTAGTAGCCCCGATGCTGTTCGTGGTAACTCCTTTTCGATGATTTACGTGGACGAATGTGTGTCGGGAGACACAATGGTTACAGTTAGAGATACGACAACCGATGAAATATTAAAAGTTACTATTGAAGAATTAAATAAAATGATAGTAAAAGATAAAATGATACAATTGAAAGGAAGGTTGTTTGAAAATCGTTACGAGATATTAACATCGAACGGCATGAAATCGTTCGATGGTGTAAAGCGAGTGGTTTCTAAAGCGATGCGAATTGTGTTGGATGATGGTAGAGAATTGACAGGATCGTACAATCATAAGGTATTGTCTGGTAATCGATACGTTAGTCTTTGTAATTTGCGCGTAGGCTCGTTTGTTGATGGTGGGAAAATAACACACATCGAAGATTGTGGAGAAATGTCATTGTATGATGCGTTAAATGTAGCAGACGGTAATCATTACACCACGAATGGAATAGAATCTCACAATTGCGCATTTATAGAAAACTTCACCGAAACTTGGAAAGCAATATTACCAGTGGTTTCGAGTGGTCGAAATTCAAAAATACTTTTGACGTCAACACCAAACGGCATGAATCACTGGTACGATTTGTGGCAAACAGCTATCAAAGACAACACAAAGGGATTTATTCCATATAGTGCCGATTGGACGTCTGTGAAAGAACGCCTTTACAACGGCGCTGATATTTTTGATGATGGTTATGAGTGGGCTATTGTACAAATTGAAAGCTCGACTATTGAAAACTTTAGACAAGAACATATGACAGTTTTTGTTGGCGCTAGTAATACGTTAATTAATGGTTTCAAATTAAGCAAAATAACCGCCGTTGACGTTGATAGTCCAGATTCTGCGTTTTATAAATTTGAAGAACCGCAAGAAAATCGTAAATATGTGTTTACAGTGGATGTATCAGAGGGCCGAGGTCAAGATTACTCCGTTATTCAAATGATCGATGTTACCGAATATCCTTACAAACAAGTGGGTCTTTATCGAAATAACAGAATATCTCATTTATTATTACCTAGCGTTATTAAGCGGTATGCTGAAATGTACAACGATGCCTATGTTTACATCGAATTAAATAGTGTTGGTGGAACTGTGGCAAAGACACTGTATGTGGATTTGGAATACGAAAATGTTATTTGTGACAGTAGTATTGATTTAGGTATGAAACAAACTAAAACAACCAAACAAATCGGTTGCTCGACTTTAAAGGATTTAATCGAAAAAGATAAATTAATAATTCGAGACAAACACACAATTTCGGAATTAAGAACATTTGTGGAACACGGTAAATCATGGGCAGCACAAAAAGGGTTTCATGATGATTGTGTAATGGGACTTGTTATATTTGCATATCTAACAACTCAGCCAAGATTTTATGATTATATCGACGAAGATAGAAACATCGGAATCGATTTATTCGAAGAAGAATTGGACGAATTATACGGTGATTTTTCGATTGGTCTAATAATATCGAATGCCGATGGTGATATTGATGTGGATAACCAACAAGATAATGCGTGGTTTTAA

Genome Context

Tertiary structure

PDB ID

a5240b20be75715b9540c95e81b06a2f60cc565674785e58975b0d3d13854b27

ESMFold

Source ESMFold

Method ESMFold

Resolution 0,7601

Oligomeric State monomer

Download PDB

Model Confidence

Very high
pLDDT > 90

High
90 > pLDDT > 70

Low
70 > pLDDT > 50

Very low
pLDDT < 50

Protein

Domains

Domains [InterPro]

Domains [InterPro]

Tail Spike Domain Segmentation

Tail Spike Domain Segmentation

3D Structure with Domain Coloring

Domain Coloring

Taxonomy

Coding sequence (CDS)

Coding sequence (CDS)

Genome Context

Genome Context

Tertiary structure

Predicted Aligned Error (PAE)

Model Confidence