Protein

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UniProt accession
P15316 [UniProt]
Protein name
Hyaluronoglucosaminidase
RBP type
TSP
Evidence DepoScope
Probability 1,00
TSP
Evidence RBPdetect2
Probability 0,96
Protein sequence
MTENIPLRVQFKRMSADEWARSDVILLEGEIGFETDTGFAKFGDGQNTFSKLKYLTGPKGPKGDTGLQGKTGGTGPRGPAGKPGTTDYDQLQNKPDLGAFAQKEETNSKITKLESSKADKSAVYSKAESKIELDKKLSLTGGIVTGQLQFKPNKSGIKPSSSVGGAINIDMSKSEGAAMVMYTNKDTTDGPLMILRSDKDTFDQSAQFVDYSGKTNAVNIVMRQPSAPNFSSALNITSANEGGSAMQIRGVEKALGTLKITHENPNVEAKYDENAAALSIDIVKKQKGGKGTAAQGIYINSTSGTAGKMLRIRNKNEDKFYVGPDGGFHSGANSTVAGNLTVKDPTSGKHAATKDYVDEKIAELKKLILKK
Physico‐chemical
properties
protein length:371 AA
molecular weight: 39518,07370 Da
isoelectric point:9,25909
aromaticity:0,05930
hydropathy:-0,60809

Domains

Domains [InterPro]
SSF69349
STR
7–369
SSF69349
IPR041352
ATT
9–46
IPR041352 G3DSA:1.20.5.320 IPR009860
P15316
1 371
Architecture
ATT
STR
ATT 7-46 | STR 47-369 |
Legend: ATT STR RBD CBM LEC ENZ CHP LNK TAS TTP UNK Unmapped

Tail Spike Domain Segmentation

Tail Spike Domain Segmentation

This protein has been segmented into three structural domains: N-terminal, central domain, and C-terminal.

Domain Layout
N-terminal
Central
C-terminal
P15316
1 371
Domain Start End Length (AA) Confidence
N-terminal 1 144 144 0,9617
Central domain 145 343 200 0,1196
C-terminal 344 371 27 0,9842
Legend: N-terminal Central domain C-terminal
3D Structure with Domain Coloring

The structure is colored according to the domain segmentation: N-terminal (blue), Central (green), C-terminal (pink).

Domain Coloring
N-terminal
1-144
Central
145-343
C-terminal
344-371

Taxonomy

  Name Taxonomy ID Lineage
Phage Streptococcus pyogenes phage H4489A
[NCBI] 		12366 Viruses >
Host Streptococcus pyogenes
[NCBI] 		1314 cellular organisms > Bacteria > Bacillati > Bacillota > Bacilli > Lactobacillales

Coding sequence (CDS)

Coding sequence (CDS)

No CDS data available.

Genome Context

Genome Context

Gene Ontology

Description Category Evidence (source)
GO:0044423 virion component Cellular Component IEA:UniProtKB-KW (UniProt)
GO:0004415 hyalurononglucosaminidase activity Molecular Function IEA:UniProtKB-EC (UniProt)
GO:0045227 capsule polysaccharide biosynthetic process Biological Process IEA:InterPro (UniProt)
GO:0098994 symbiont entry into host cell via disruption of host cell envelope Biological Process IEA:UniProtKB-KW (UniProt)
GO:0098996 symbiont entry into host cell via disruption of host cell glycocalyx Biological Process IEA:UniProtKB-KW (UniProt)

Tertiary structure

1 / 5
PDB ID
Source
Method
Resolution
Oligomeric State

Literature

Title Authors Date PMID Source
— — 2643574 PubMed