Protein

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UniProt accession
A0A9E7LPJ8 [UniProt]
Protein name
Peptidase S74 domain-containing protein
RBP type
TF
Evidence Phold
Probability 1,00
TSP
Evidence DepoScope
Probability 1,00
TSP
Evidence RBPdetect
Probability 0,91
TSP
Evidence RBPdetect2
Probability 0,94
Protein sequence
MAKLTKPNTEGILHKGQSLYEYLDARVLTSKPFGAVGDATTDDTEVIAASLNSQKAVTVSDGVFSSSGINSNYCNLDGRGSGVLSHRSSTGNYLVFNNLRAGRLSNITVESNKATDTTQGQQVSLAGGSDVTVSDVNFSNVKGTGFSLIAYPNDAPPDGLMIKGIRGSYSGYATNKAAGCVLADSSVNSLIDNVIAKNYPQFGAVELKGTASYNIVSNVIGADCQHVTYNGTEGPIAPSNNLINGVVANNPKYAAVVAGKGSTNLISDVLVDYSTSDARQAHGVTVEGSDNVINNVLMSGCDGTNSLGQSQTATIARFRGTANNNYASVFPSYSATGVITFESGSTRNFVEVKHPGRRNDLLSSASTIDGAATIDGTSNSNVVHAPALGQYIGSMSGRFEWRIKSMSLPSGVLTSADKYRMLGDGAVSLAVGGGTSSQIRLFTSDGTSRTVSLTNGNVRLSTSSTGFLQLGADAMTPDSTGTYALGSASRAWSGGFTQAAFTVTSDARCKTEPLTISDALLDAWSEVDFVQFQYLDRVEEKGADSARWHFGIIAQRAKEAFERHGIDAHRYGFLCFDSWDDVYEEDANGSRKLITPAGSRYGIRYEEVLILEAALMRRTIKRMQEALASLPK
Physico‐chemical
properties
protein length:632 AA
molecular weight: 66787,27720 Da
isoelectric point:5,79584
aromaticity:0,07595
hydropathy:-0,20854

Domains

Domains [InterPro]
IPR012334
STR
7–505
IPR012334 IPR030392
IPR011050
STR
38–306
IPR011050 IPR030392
cd10144
CHP
505–618
cd10144
cd10144
CHP
505–610
cd10144
IPR036388
RBD
506–628
IPR036388
A0A9E7LPJ8
1 632
Architecture
STR
RBD
STR 7-505 | RBD 506-630 |
Legend: ATT STR RBD CBM LEC ENZ CHP LNK TAS TTP UNK Unmapped

Tail Spike Domain Segmentation

Tail Spike Domain Segmentation

This protein has been segmented into three structural domains: N-terminal, central domain, and C-terminal.

Domain Layout
N-terminal
Central
C-terminal
A0A9E7LPJ8
1 632
Domain Start End Length (AA) Confidence
N-terminal 1 42 42 0,9276
Central domain 43 399 358 0,9798
C-terminal 400 632 232 0,9609
Legend: N-terminal Central domain C-terminal
3D Structure with Domain Coloring

The structure is colored according to the domain segmentation: N-terminal (blue), Central (green), C-terminal (pink).

Domain Coloring
N-terminal
1-42
Central
43-399
C-terminal
400-632

Taxonomy

  Name Taxonomy ID Lineage
Phage Escherichia phage EEc2
[NCBI] 		2950297 Uroviricota > Caudoviricetes > Autographivirales > Molineuxvirinae > Vectrevirus
Host Escherichia coli
[NCBI] 		562 cellular organisms > Bacteria > Pseudomonadati > Pseudomonadota > Gammaproteobacteria > Enterobacterales

Coding sequence (CDS)

Coding sequence (CDS)

No CDS data available.

Genome Context

Genome Context

Gene Ontology

Description Category Evidence (source)
GO:0098015 virus tail Cellular Component IEA:UniProtKB-KW (UniProt)
GO:0098994 symbiont entry into host cell via disruption of host cell envelope Biological Process IEA:UniProtKB-KW (UniProt)
GO:0098996 symbiont entry into host cell via disruption of host cell glycocalyx Biological Process IEA:UniProtKB-KW (UniProt)

Tertiary structure

PDB ID
077058c92169d47df3a82ac91b58a49347a3eccbfc733eb4db3e42168a40bb38
ESMFold
Source ESMFold
Method ESMFold
Resolution 0,7798
Oligomeric State monomer
Download PDB
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50