Protein

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UniProt accession
A0AAE8C3A2 [UniProt]
Protein name
Peptidase S74 domain-containing protein
RBP type
TF
Evidence Phold
Probability 1,00
TSP
Evidence DepoScope
Probability 1,00
TSP
Evidence RBPdetect
Probability 0,90
TSP
Evidence RBPdetect2
Probability 0,92
Protein sequence
MAKLTRVTDWLVKVKSRLTGAVERLLEDKLNDTVSVKDFGAKGDGVTDDTQAFAAASAASPQGVYVPDGTYLLPEDINGRFYGSGKRIKAVGDGGIPFTNVAQSHSNLILGYDAAKDYTDEGKGNQLVLLGPSSGRNLTTGTNSIVVGVGGLSGDTLEDALTDKSPFTGTEIISIGINALKKTTTGNNMIGIGRDALNECKDGRFNVAVGMSALQQLHSGEANVAIGRSAGMRTGIFTNEEGVRLGYTKCSGNTLIGNAAGRELKSGNHNTAVGNGAMRGVSSDINPYTGTLEGNFNTAIGVDTLNSLASGELNTMIGARAGRKLPSGSGNIFIGADAGAGINVEKSNTLIINNHTGLPFVEGIMGGAQSGNNYLRVDGSVAPQIDNTRTCGQSSRRWQTVFATNGVIQTSDGRCKDVYDIAKKEYMAGLELASSMIKFKWTDTEEDKYHFGCLAQEVMLIMEKHGLNPLDYSLVTYDAEADMYGVNYAELSCFCIAAMSNHVLGSA
Physico‐chemical
properties
protein length:507 AA
molecular weight: 53342,19620 Da
isoelectric point:5,41684
aromaticity:0,06312
hydropathy:-0,20178

Domains

Domains [InterPro]
DC_1226
STR
2–499
DC_1226
IPR012334
STR
14–205
IPR012334 IPR044914 IPR036388
IPR011050
STR
31–84
IPR011050 IPR030392
IPR011050
STR
32–356
IPR011050
IPR024535
ENZ
34–149
IPR024535
A0AAE8C3A2
1 507
Architecture
STR
STR 2-507
Legend: ATT STR RBD CBM LEC ENZ CHP LNK TAS TTP UNK Unmapped

Tail Spike Domain Segmentation

Tail Spike Domain Segmentation

This protein has been segmented into three structural domains: N-terminal, central domain, and C-terminal.

Domain Layout
N-terminal
Central
C-terminal
A0AAE8C3A2
1 507
Domain Start End Length (AA) Confidence
N-terminal 1 50 50 0,9733
Central domain 51 351 302 0,9576
C-terminal 352 507 155 0,9661
Legend: N-terminal Central domain C-terminal
3D Structure with Domain Coloring

The structure is colored according to the domain segmentation: N-terminal (blue), Central (green), C-terminal (pink).

Domain Coloring
N-terminal
1-50
Central
51-351
C-terminal
352-507

Taxonomy

  Name Taxonomy ID Lineage
Phage Escherichia phage vB_EcoP-101117UKE2
[NCBI] 		2865796 Uroviricota > Caudoviricetes > Autographivirales > Molineuxvirinae > Rodentiumvirus
Host Escherichia coli
[NCBI] 		562 cellular organisms > Bacteria > Pseudomonadati > Pseudomonadota > Gammaproteobacteria > Enterobacterales

Coding sequence (CDS)

Coding sequence (CDS)

No CDS data available.

Genome Context

Genome Context

Gene Ontology

Description Category Evidence (source)
GO:0098015 virus tail Cellular Component IEA:UniProtKB-KW (UniProt)
GO:0098994 symbiont entry into host cell via disruption of host cell envelope Biological Process IEA:UniProtKB-KW (UniProt)
GO:0098996 symbiont entry into host cell via disruption of host cell glycocalyx Biological Process IEA:UniProtKB-KW (UniProt)

Tertiary structure

PDB ID
0e4e7d5718a031efbb82b59a56db7d96f7672279435cd6ee4370fe929b2fb564
ESMFold
Source ESMFold
Method ESMFold
Resolution 0,7763
Oligomeric State monomer
Download PDB
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50