Protein

View in Explore
Genbank accession
QBX29437.1 [GenBank]
Protein name
hyaluronate lyase
RBP type
TSP
Evidence DepoScope
Probability 1,00
TSP
Evidence RBPdetect2
Probability 0,95
Protein sequence
MRLHKKKETDNKIAKLESIKADKDTVYLKAESKKELDKKMNLTGGTMTGQLQFKPNSHIKHSSSTGGAINIDMSKSAGAAMVMYTNKDTTDGPLMILRSDKDTFDQSAQFVDYSGKTNAVNIVMRQPSTPNFSSALNITSANEGGSAMQIRGIERALGTLKITHENPNVDAKYDENAAALSIDIVGKRGASGNGTAAQGIFINSSAGTTGKMLRIRNKNKDKFYVNPDGGFHSYADSIVDGNLTVKDPTSGKHAATKDYVDKKFDELKKLIQKTD
Physico‐chemical
properties
protein length:275 AA
molecular weight: 29816,32360 Da
isoelectric point:9,39706
aromaticity:0,05455
hydropathy:-0,65855

Domains

Domains [InterPro]
SSF69349
STR
4–272
SSF69349
IPR009860
STR
65–232
IPR009860
QBX29437.1
1 275
Architecture
STR
STR 4-272 |
Legend: ATT STR RBD CBM LEC ENZ CHP LNK TAS TTP UNK Unmapped

Tail Spike Domain Segmentation

Tail Spike Domain Segmentation

This protein has been segmented into three structural domains: N-terminal, central domain, and C-terminal.

Domain Layout
N-terminal
Central
C-terminal
QBX29437.1
1 275
Domain Start End Length (AA) Confidence
N-terminal 1 27 27 0,9516
Central domain 28 226 200 0,1401
C-terminal 227 275 48 0,9099
Legend: N-terminal Central domain C-terminal
3D Structure with Domain Coloring

The structure is colored according to the domain segmentation: N-terminal (blue), Central (green), C-terminal (pink).

Domain Coloring
N-terminal
1-27
Central
28-226
C-terminal
227-275

Taxonomy

  Name Taxonomy ID Lineage
Phage Streptococcus phage Javan496
[NCBI] 		2548210 Viruses > Duplodnaviria > Heunggongvirae > Uroviricota > Caudoviricetes
Host Streptococcus pyogenes MGAS10394
[NCBI] 		286636 Bacillota > Bacilli > Lactobacillales > Streptococcaceae > Streptococcus > Streptococcus pyogenes

Coding sequence (CDS)

Coding sequence (CDS)
Genbank protein accession
QBX29437.1 [NCBI]
Genbank nucleotide accession
MK448962 [NCBI]
CDS location
range 23043 -> 23870
strand +
CDS
ATGCGTTTGCACAAAAAAAAAGAAACTGATAATAAAATCGCCAAATTAGAATCAATTAAAGCAGACAAAGACACTGTTTACTTAAAAGCAGAGTCAAAAAAAGAGCTAGACAAAAAAATGAATTTGACAGGCGGCACAATGACAGGACAACTACAGTTTAAACCTAATAGTCATATTAAGCACTCATCTTCTACAGGAGGAGCGATTAACATTGATATGTCTAAATCAGCAGGTGCTGCTATGGTGATGTATACAAATAAAGATACTACTGATGGACCATTGATGATTTTACGCTCTGACAAAGATACGTTTGATCAGTCAGCTCAATTTGTGGATTACAGCGGTAAGACTAATGCTGTAAATATTGTAATGCGCCAGCCAAGCACACCTAATTTTTCCTCAGCACTTAATATAACCAGTGCTAATGAAGGCGGTAGTGCGATGCAAATTAGAGGCATCGAAAGAGCATTGGGAACACTCAAAATCACACACGAAAACCCAAACGTTGACGCAAAATACGATGAAAACGCTGCAGCGTTATCTATTGATATCGTTGGAAAACGGGGAGCCAGTGGAAATGGTACTGCTGCACAAGGCATTTTCATCAATTCGTCCGCAGGCACAACTGGTAAAATGCTCAGAATCAGAAATAAAAATAAAGACAAATTTTATGTAAATCCAGATGGCGGCTTTCACTCATATGCAGATTCAATCGTGGATGGTAATCTAACAGTTAAAGATCCAACATCTGGAAAACATGCTGCGACTAAAGATTACGTAGATAAAAAATTTGATGAGTTAAAAAAACTCATACAAAAAACAGATTAA

Genome Context

Genome Context

Tertiary structure

PDB ID
59ae3eb3cdf1be94e3d1a8ce225b6b48669e5b42102d71470bc04a0b2ba2e4ad
ESMFold
Source ESMFold
Method ESMFold
Resolution 0,7763
Oligomeric State monomer
Download PDB
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50

Literature

Title Authors Date PMID Source
Prophages and satellite prophages are widespread among Streptococcus species and may play a role in pneumococcal pathogenesis Rezaei Javan,R., Ramos-Sevillano,E., Akter,A., Brown,J. and Brueggemann,A.B. 2018-12-20 — GenBank