Protein

UniProt accession

A0A1S6KVE9 [UniProt]

Protein name

Catalytic beta propeller domain of endosialidase

RBP type

TSP

Evidence DepoScope

Probability 1,00

TSP

Evidence RBPdetect

Probability 0,90

TSP

Evidence RBPdetect2

Probability 0,94

Evidence Phold

Probability 1,00

Protein sequence

MSTITQFPSGNTQYRIEFDYLARTFVVVTLVNSSNPTLNRVLEVGRDYRFLNPTMIEMLVDQSGFDIVRIHRQTGTDLVVDFRNGSVLTASDLTNSELQAIHIAEEGRDQTVDLAKEYADAAGSSAGNAKDSEDEARRIAASIRAAGLIGYITRRSFEKGYNVTTWSEVLLWEEDGDYYRWDGTLPKNVPAGSTPETSGGIGLGAWVSVGDAALRSQISNPEGAILYPELHRARWLDEKDVRGWGAKGDGVTDDTAALTSALNDTPVGQKINGNGKTYKVTSLPDISRFINTRFVYERIPGQPLYYASEEFVQGELFKITDTPYYNAWPQDKAFVYENVIYAPYMGSDRHGVSRLHVSWVKSGDDGQTWSTPEWLTDLHPDYPTVNYHCMSMGVCRNRLFAMIETRTLAKNALTNCALWDRPMSRSLHLTGGITKAANQRYATIHVPDHGLFVGDFVNFSNSAVTGVSGDMTVATVIDKDNFTVLTPNQQTSDLNNAGTNWHMGTSFHKSPWRKTDLGLIPSVTEVHSFATIDNNGFVMGYHQGDVAPREVGLFYFPDAFNSPSNYVRRRIPSEYEPDAAEPCIKYYDGVLYLITRGTRGDRLGSSLHRSRDIGQTWESLRFPHNVHHTTLPFAKVGDDLIMFGSERAENEWEAGAPDDRYKASYPRTFYARLNVNNWNADDIEWVNITDQIYQGGIVNSGVGVGSVVVKDNYIYYMFGGEDHFNPWTYGDNSAKDPFKADGHPSDLYCYKMKIGPSNHVSRDFRYGAVPNRAVPVFFDTNGIRTVPAPMEFTGDLGLGHVTIRASTSSNIRSEVLMEGEYGFIGKSIPTDNPAGQRIIFCGGEGTSSTTGAQITLYGANNTDSRRIVYNGAEHLFQTADVKPYNDNVTALGGPSNRFTTAYLGSNPIVTSNGEKKTEPVVFDDAFLDAWGDVRYIMYQWLDAVQLKGNDARIHFGVIAQQIRDVFIAHGLMDENSTNCRYAVLCYDKYQRMTDTVFSHNEIVEHTDEEGNVTTTEEPVYTEVVIHEEGEEWGVRPDGIFFAEAAYQRRKLERIEARLSALEQK

Physico‐chemical properties

protein length:	1064 AA
molecular weight:	118840,62830 Da
isoelectric point:	5,17754
aromaticity:	0,10996
hydropathy:	-0,44192

Domains

Domains [InterPro]

IPR005604
10–113

IPR005604 G3DSA:2.10.10.80 G3DSA:3.30.750.60 IPR024428 IPR024430 cd10144

IPR040775
156–211

IPR040775 IPR036278 SSF69349 IPR030392

IPR024429
246–312

IPR024429 G3DSA:2.120.10.10 IPR044914 IPR030392 G3DSA:3.30.2460.10 G3DSA:1.20.5.100

IPR001724
314–338

IPR001724 IPR001724 IPR024427 IPR001724 IPR001724 IPR001724 IPR001724 IPR001724 G3DSA:1.20.5.1240 Coil

IPR023366
424–510

IPR023366

IPR001724
498–521

IPR001724

A0A1S6KVE9

1 1064

Legend: Pfam SMART CDD TIGRFAM HAMAP SUPFAM PRINTS Gene3D PANTHER Other

Domains [InterPro]

InterPro ID	Start	End	Source	Name
IPR005604	10	113	InterPro	Bacteriophage T7 tail fibre protein-like, N-terminal domain
G3DSA:2.10.10.80	150	220	Gene3D	None
IPR040775	156	211	InterPro	Tail spike TSP1/Gp66, N-terminal domain
G3DSA:3.30.750.60	241	312	Gene3D	None
IPR036278	245	760	InterPro	Sialidase superfamily
IPR024429	246	312	InterPro	Endosialidase, N-terminal extension domain
IPR024428	313	754	InterPro	Endosialidase, beta-propeller domain
G3DSA:2.120.10.10	314	754	Gene3D	None
IPR001724	314	338	InterPro	Glycosyl hydrolase 58
IPR001724	379	407	InterPro	Glycosyl hydrolase 58
IPR024427	424	506	InterPro	Endosialidase, beta-barrel domain
IPR023366	424	510	InterPro	ATP synthase subunit alpha, N-terminal domain-like superfamily
IPR001724	498	521	InterPro	Glycosyl hydrolase 58
IPR001724	568	594	InterPro	Glycosyl hydrolase 58
IPR001724	646	672	InterPro	Glycosyl hydrolase 58
IPR001724	702	726	InterPro	Glycosyl hydrolase 58
IPR024430	757	910	InterPro	Endosialidase, C-terminal domain
IPR044914	757	910	InterPro	Endosialidase, C-terminal domain superfamily
SSF69349	761	910	SUPERFAMILY	None
IPR001724	803	829	InterPro	Glycosyl hydrolase 58
IPR001724	835	862	InterPro	Glycosyl hydrolase 58
cd10144	911	1050	CDD	None
IPR030392	911	1064	InterPro	Intramolecular chaperone auto-processing domain
IPR030392	915	971	InterPro	Intramolecular chaperone auto-processing domain
G3DSA:1.20.5.1240	924	975	Gene3D	None
G3DSA:3.30.2460.10	976	1034	Gene3D	None
G3DSA:1.20.5.100	1035	1064	Gene3D	None
Coil	1044	1064	Coils	None

Taxonomy

	Name	Taxonomy ID	Lineage
Phage	Escherichia phage vB_EcoP_F [NCBI]	1933110	Viruses > Duplodnaviria > Heunggongvirae > Uroviricota > Caudoviricetes
Host	No host information

Coding sequence (CDS)

No CDS data available.

Gene Ontology

	Description	Category	Evidence (source)
GO:0098015	virus tail	Cellular Component	IEA:UniProtKB-KW (UniProt)
GO:0016996	endo-alpha-(2,8)-sialidase activity	Molecular Function	IEA:InterPro (UniProt)
GO:0098671	adhesion receptor-mediated virion attachment to host cell	Biological Process	IEA:UniProtKB-KW (UniProt)
GO:0046718	symbiont entry into host cell	Biological Process	IEA:UniProtKB-KW (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

PDB ID

3220dab08b3755df6bb84cf31bb17e9ce1849814310feb50cc64720a7ae9ac37

ESMFold

Source ESMFold

Method ESMFold

Resolution 0,6657

Evidence 0,6657

Download PDB

Literature

No literature entries available.