Protein

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UniProt accession

C6ZCZ5 [UniProt]

Protein name

Tail:host specificity protein

RBP type

Evidence UniProt/TrEMBL

Probability 1,00

Evidence GenBank

Probability 1,00

Evidence Phold

Probability 1,00

TSP

Evidence RBPdetect

Probability 0,88

Evidence RBPdetect2

Probability 0,95

Protein sequence

MGKGSSKGHTPREAKDNLKSTQLLSVIDAISEGPIEGPVDGLKSVLLNSTPVLDTEGNTNISGVTVVFRAGEQEQTPPEGFESSGSETVLGTEVKYDTPITRTITSANIDRLRFTFGVQALVETTSKGDRNPSEVRLLVQIQRNGGWVTEKDITIKGKTTSQYLASVVMGNLPPRPFNIRMRRMTPDSTTDQLQNKTLWSSYTEIIDVKQCYPNTALVGVQVDSEQFGSQQVSRNYHLRGRILQVPSNYNPQTRQYSGIWDGTFKPAYSNNMAWCLWDMLTHPRYGMGKRLGAADVDKWALYVIGQYCDQSVPDGFGGTEPRITCNAYLTTQRKAWDVLSDFCSAMRCMPVWNGQTLTFVQDRPSDKTWTYNRSNVVMPDDGAPFRYSFSALKDRHNAVEVNWIDPNNGWETATELVEDTQAIARYGRNVTKMDAFGCTSRGQAHRAGLWLIKTELLETQTVDFSVGAEGLRHVPGDVIEICDDDYAGISTGGRVLAVNSQTRTLTLDREITLPSSGTALISLVDGSGNPVSVEVQSVTDGVKVKVSRVPDGVAEYSVWELKLPTLRQRLFRCVSIRENDDGTYAITAVQHVPEKEAIVDNGAHFDGEQSGTVNGVTPPAVQHLTAEVTADSGEYQVLARWDTPKVVKGVSFLLRLTVTADDGSERLVSTARTTETTYRFTQLALGNYRLTVRAVNAWGQQGDPASVSFRIAAPAAPSRIELTPGYFQITATPHLAVYDPTVQFEFWFSEKQIADIRQVETSTRYLGTALYWIAASINIKPGHDYYFYIRSVNTVGKSAFVEAVGRASDDAEGYLDFFKGKITESHLGKELLEKVELTEDNASRLEEFSKEWKDASDKWNAMWAVKIEQTKDGKHYVAGIGLSMEDTEEGKLSQFLVAANRIAFIDPANGNETPMFVAQGNQIFMNDVFLKRLTAPTITSGGNPPAFSLTPDGKLTAKNADISGSVNANSGTLSNVTIAENCTINGTLRAEKIVGDIVKAASAAFPRQRESSVDWPSGTRTVTVTDDHPFDRQIVVLPLTFRGSKRTVSGRTTYSMCYLKVLMNGAVIYDGAANEAVQVFSRIVDMPAGRGNVILTFTLTSTRHSADIPPYTFASDVQVMVIKKQALGISVV

Physico‐chemical properties

protein length:	1132 AA
molecular weight:	124420,46210 Da
isoelectric point:	5,67079
aromaticity:	0,08392
hydropathy:	-0,30451

Domains

Domains [InterPro]

IPR053171
Unmapped
1–840

IPR053171 IPR015406 IPR021034

DC_0014
STR
1–1128

DC_0014

IPR055385
ATT
86–207

IPR055385 IPR032876 IPR013783

IPR055383
STR
610–714

IPR055383 IPR003961

IPR036116
STR
617–719

IPR036116

IPR003961
STR
618–710

IPR003961 IPR057587

IPR003961
STR
618–701

IPR003961

IPR003961
STR
620–715

IPR003961

C6ZCZ5

1 1132

Architecture

STR

ATT

STR

ATT

STR

ATT

STR

STR 1-85 | ATT 86-207 | STR 208-330 | ATT 331-498 | STR 499-715 | ATT 716-818 | STR 819-1132

Legend: ATT STR RBD CBM LEC ENZ CHP LNK TAS TTP UNK Unmapped

Domains [InterPro]

Domain ID	Category	Cluster	Start	End	Layer	Name	Pref Zone	Confidence	Evidence	Support
IPR053171	Unmapped	-	1	840	InterPro	Viral Tip Attachment Protein	-	-	-	-
DC_0014	STR	DC_0014	1	1128	Novel HMM	DC_0014	Central	Low	Positional only	830 proteins / 830 hits
IPR055385	ATT	DC_0360	86	207	InterPro cluster	Tip attachment protein J, HDII-ins2 domain	N-terminal	High	Text match	1136 proteins / 1139 hits
IPR032876	ATT	DC_0307	331	498	InterPro cluster	Tip attachment protein J	Central	Medium	Text match	1111 proteins / 1112 hits
IPR013783	STR	IPR013783	608	719	Merged direct domain	Immunoglobulin-like fold	Central	Low	Positional only	144 proteins / 144 hits
IPR055383	STR	DC_0003	610	714	InterPro cluster	Tip attachment protein J, Fn3-1 domain	Central	High	Text match	998 proteins / 1603 hits
IPR036116	STR	IPR036116	617	719	Merged direct domain	Fibronectin type III superfamily	Central	Low	Positional only	52 proteins / 52 hits
IPR003961	STR	DC_0003	618	710	InterPro cluster	Fibronectin type III	Central	High	Text match	998 proteins / 1603 hits
IPR003961	STR	DC_0003	618	701	InterPro cluster	Fibronectin type III	Central	High	Text match	998 proteins / 1603 hits
IPR003961	STR	DC_0003	620	715	InterPro cluster	Fibronectin type III	Central	High	Text match	998 proteins / 1603 hits
IPR003961	STR	DC_0003	714	798	InterPro cluster	Fibronectin type III	Central	High	Text match	998 proteins / 1603 hits
IPR057587	ATT	DC_0130	716	818	InterPro cluster	Tip attachment protein J, second Ig-like domain	Central	Medium	Text match	309 proteins / 309 hits
IPR015406	RBD	DC_0135	845	972	InterPro cluster	Tip attachment protein J, central straight fiber domain	C-terminal	High	Text match	1265 proteins / 1266 hits
IPR021034	RBD	DC_0391	1001	1132	InterPro cluster	Tip attachment protein J, C-terminal receptor binding domain	C-terminal	High	Text match	123 proteins / 123 hits

Tail Spike Domain Segmentation

This protein has been segmented into three structural domains: N-terminal, central domain, and C-terminal.

Domain Layout

N-terminal

Central

C-terminal

C6ZCZ5

1 1132

Domain	Start	End	Length (AA)	Confidence
N-terminal	1	993	993	0,8979
Central domain	994	1121	129	0,2224
C-terminal	1122	1132	10	0,9867

Note: Constraints were applied during segmentation.
Fixed 45 C-terminal predictions appearing before Central domain|Sequence started with non-N-terminal domain|C-terminal too short, adjusted boundary

Legend: N-terminal Central domain C-terminal

3D Structure with Domain Coloring

The structure is colored according to the domain segmentation: N-terminal (blue), Central (green), C-terminal (pink).

Domain Coloring

N-terminal
1-993

Central
994-1121

C-terminal
1122-1132

Taxonomy

	Name	Taxonomy ID	Lineage
Phage	Escherichia phage DE3 [NCBI]	482822	Uroviricota > Caudoviricetes > Lambdavirus > Escherichia virus DE3 >
Host	Escherichia coli [NCBI]	562	cellular organisms > Bacteria > Pseudomonadati > Pseudomonadota > Gammaproteobacteria > Enterobacterales

Coding sequence (CDS)

No CDS data available.

Genome Context

Tertiary structure

1 / 9

PDB ID

Source

Method

Resolution

Oligomeric State

Protein

Domains

Domains [InterPro]

Domains [InterPro]

Tail Spike Domain Segmentation

Tail Spike Domain Segmentation

3D Structure with Domain Coloring

Domain Coloring

Taxonomy

Coding sequence (CDS)

Coding sequence (CDS)

Genome Context

Genome Context

Tertiary structure

Predicted Aligned Error (PAE)