Protein

View in Explore
UniProt accession
A0AAE8Y2R4 [UniProt]
Protein name
K5 lyase
RBP type
TF
Evidence Phold
Probability 1,00
TSP
Evidence DepoScope
Probability 1,00
TSP
Evidence RBPdetect
Probability 0,91
TSP
Evidence RBPdetect2
Probability 0,94
Protein sequence
MAKLTKPNTEGILHKGQSLYEYLDARVLTSKPFGAAGDATTDDTEVIAASLNSQKAVTVSDGVFSSSGINSNYCNLDGRGSGVLSHRSSTGNYLVFNNLRAGRLSNITVESNKETDTTQGQQVSLAGGSDVTVSDVNFSNVKGTGFSLIAYPNDAPPDGLMIKGIRGSYSGYATNKAAGCVLADSSVNSLIDNVIAKNYPQFGAVELKGTASYNIVSNVIGADCQHVTYNGTEGPIAPSNNLIKGVMANNPKYAAVVAGKGSTNLISDVLVDYSTSDARQAHGVTVEGSDNVINNVLMSGCDGTNSLGQGQTATIARFIGTANNNYASVFPSYSATGVITFESGSTRNFVEVKHPGRRNDLLSSASTIDGAATIDGTSNSNVVHAPALGQYIGSMSGRFEWRIKSMSLPSGVLTSADKYRMLGDGAVSLAVGGGTSSQVRLFTSDGTSRTVAFTNGNVRLSTSSTGYLQLGADAMTPDSTGTYALGSASRAWSGGFTQAAFTVTSDARCKTEPLTISDALLDAWSEVDFVQFQYLDRVEEKGADSARWHFGVIAQRAKEAFERHGIDAHRYGFLCFDSWDAVYEEDANGSRKLITPAGSRYGIRYEEVLILEAALMRRTIKRMQEALAALHK
Physico‐chemical
properties
protein length:632 AA
molecular weight: 66776,31900 Da
isoelectric point:5,86461
aromaticity:0,07753
hydropathy:-0,20506

Domains

Domains [InterPro]
IPR012334
STR
7–505
IPR012334 IPR030392
IPR011050
STR
38–306
IPR011050 cd10144
IPR030392
CHP
505–565
IPR030392
cd10144
CHP
505–610
cd10144
IPR036388
RBD
506–631
IPR036388
A0AAE8Y2R4
1 632
Architecture
STR
RBD
STR 7-505 | RBD 506-631 |
Legend: ATT STR RBD CBM LEC ENZ CHP LNK TAS TTP UNK Unmapped

Tail Spike Domain Segmentation

Tail Spike Domain Segmentation

This protein has been segmented into three structural domains: N-terminal, central domain, and C-terminal.

Domain Layout
N-terminal
Central
C-terminal
A0AAE8Y2R4
1 632
Domain Start End Length (AA) Confidence
N-terminal 1 41 41 0,9226
Central domain 42 400 360 0,9797
C-terminal 401 632 231 0,9598
Legend: N-terminal Central domain C-terminal
3D Structure with Domain Coloring

The structure is colored according to the domain segmentation: N-terminal (blue), Central (green), C-terminal (pink).

Domain Coloring
N-terminal
1-41
Central
42-400
C-terminal
401-632

Taxonomy

  Name Taxonomy ID Lineage
Phage Escherichia phage ULINTec7
[NCBI] 		2876731 Uroviricota > Caudoviricetes > Autographivirales > Molineuxvirinae > Vectrevirus
Host Escherichia coli
[NCBI] 		562 cellular organisms > Bacteria > Pseudomonadati > Pseudomonadota > Gammaproteobacteria > Enterobacterales

Coding sequence (CDS)

Coding sequence (CDS)

No CDS data available.

Genome Context

Genome Context

Gene Ontology

Description Category Evidence (source)
GO:0098015 virus tail Cellular Component IEA:UniProtKB-KW (UniProt)
GO:0016829 lyase activity Molecular Function IEA:UniProtKB-KW (UniProt)
GO:0098994 symbiont entry into host cell via disruption of host cell envelope Biological Process IEA:UniProtKB-KW (UniProt)
GO:0098996 symbiont entry into host cell via disruption of host cell glycocalyx Biological Process IEA:UniProtKB-KW (UniProt)

Tertiary structure

PDB ID
fb75c837dcb4b23323353a0e9ecac66a0cf488294abfb37504fb5d0da5bcd4a3
ESMFold
Source ESMFold
Method ESMFold
Resolution 0,7799
Oligomeric State monomer
Download PDB
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50