Protein

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UniProt accession

A0AAF0D7Y3 [UniProt]

Protein name

Probable tail spike protein

RBP type

Evidence Phold

Probability 1,00

TSP

Evidence DepoScope

Probability 1,00

TSP

Evidence RBPdetect

Probability 0,91

TSP

Evidence RBPdetect2

Probability 0,94

Protein sequence

MIKTDFNQPKGSTIGVLKDGRTVQQAFDQSVYVPIEQFGAKGDGISDDTAALQLALSSGKNLSLYGTYLVKSTLSITKDGQKLAGSGTLKIDVAATTLLKSLGASNVRIEGITLQSSSADTNTYNGSCIWAENCSGWVISGCLFRDYKASAVFINKSSNFRVTHNTFRGAAGAAGDVTMWRSCSGNLVSANDMTSGSDTAIVLQTIEDGDVSVDNMISFNRIANCTRYGIVVYNSLERKVGSLLRTRIIGNSIDTIHGSVTNPSAGNAKTYGAGIYVLSAEGIVVSDNVVSRCNLETNSSTLSPGCIGVNATSSAIISNNAVSGGGYHGIFISDALQQGAGNSAGSAAYRPIGGVVLSGNTATSCVRDGIHIENKHSVKLIGNTCTHNSGNGVVVYTTSGGVNYPSMVDIAVLSCTSLRNGLAGLSLSNCQSPQAIGGSFSWNSGDGVSTSSPASVLSNLMTEGNSRGIVMSAAALNCSVTLCRVNGNATGLVAFSPYLFDNNSINGNTTDFNGNYGPVKNLTGSSTPSAKFVKVITLGDATTITDLLDGELGQTVVIRAAANGTTITHNTNSIRLNGSVDFVMQAGDTLTLTKFFQNQWDEVSRMTRAVVTS

Physico‐chemical properties

protein length:	613 AA
molecular weight:	63577,33880 Da
isoelectric point:	7,00475
aromaticity:	0,06036
hydropathy:	0,01566

Domains

Domains [InterPro]

DC_1550
ATT
2–35

DC_1550 IPR024535 IPR039448 IPR006626 IPR006626 IPR006626 IPR006626 IPR006626 IPR006626 IPR006626 IPR006626 IPR057996

IPR011050
STR
29–292

IPR011050 IPR012334

IPR012334
STR
34–301

IPR012334 DC_1714

IPR006626
Unmapped
104–133

IPR006626 IPR006626 IPR006626 IPR006626 IPR006626 IPR011050 IPR006626

IPR039448
ENZ
270–401

IPR039448

A0AAF0D7Y3

1 613

Architecture

ATT

STR

RBD

ATT 2-35 | STR 36-598 | RBD 599-613

Legend: ATT STR RBD CBM LEC ENZ CHP LNK TAS TTP UNK Unmapped

Domains [InterPro]

Domain ID	Category	Cluster	Start	End	Layer	Name	Pref Zone	Confidence	Evidence	Support
DC_1550	ATT	DC_1550	2	35	Novel HMM	DC_1550	N-terminal	Low	Positional only	65 proteins / 65 hits
IPR011050	STR	IPR011050	29	292	Merged direct domain	Pectin lyase fold/virulence factor	Central	Low	Positional only	572 proteins / 572 hits
IPR012334	STR	IPR012334	34	301	Merged direct domain	Pectin lyase fold	Central	Low	Positional only	867 proteins / 867 hits
IPR024535	ENZ	DC_0410	35	96	InterPro cluster	Rhamnogalacturonase A/B/Epimerase-like, pectate lyase domain	Central	High	Text match	420 proteins / 426 hits
IPR039448	ENZ	DC_0799	103	239	InterPro cluster	Right handed beta helix domain	C-terminal	High	Text match	178 proteins / 183 hits
IPR006626	Unmapped	-	104	133	InterPro	Parallel beta-helix repeat	-	-	-	-
IPR006626	Unmapped	-	134	156	InterPro	Parallel beta-helix repeat	-	-	-	-
IPR006626	Unmapped	-	157	178	InterPro	Parallel beta-helix repeat	-	-	-	-
IPR006626	Unmapped	-	183	205	InterPro	Parallel beta-helix repeat	-	-	-	-
IPR006626	Unmapped	-	212	234	InterPro	Parallel beta-helix repeat	-	-	-	-
IPR006626	Unmapped	-	243	279	InterPro	Parallel beta-helix repeat	-	-	-	-
IPR011050	STR	IPR011050	269	398	Merged direct domain	Pectin lyase fold/virulence factor	Central	Low	Positional only	572 proteins / 572 hits
IPR039448	ENZ	DC_0799	270	401	InterPro cluster	Right handed beta helix domain	C-terminal	High	Text match	178 proteins / 183 hits
IPR006626	Unmapped	-	280	311	InterPro	Parallel beta-helix repeat	-	-	-	-
IPR012334	STR	IPR012334	302	598	Merged direct domain	Pectin lyase fold	Central	Low	Positional only	867 proteins / 867 hits
IPR006626	Unmapped	-	312	334	InterPro	Parallel beta-helix repeat	-	-	-	-
IPR006626	Unmapped	-	352	374	InterPro	Parallel beta-helix repeat	-	-	-	-
DC_1714	RBD	DC_1714	357	613	Novel HMM	DC_1714	C-terminal	Low	Positional only	24 proteins / 24 hits
IPR006626	Unmapped	-	375	397	InterPro	Parallel beta-helix repeat	-	-	-	-
IPR006626	Unmapped	-	407	429	InterPro	Parallel beta-helix repeat	-	-	-	-
IPR006626	Unmapped	-	452	473	InterPro	Parallel beta-helix repeat	-	-	-	-
IPR006626	Unmapped	-	475	496	InterPro	Parallel beta-helix repeat	-	-	-	-
IPR057996	ENZ	DC_0294	520	592	InterPro cluster	Depolymerase 2 capsule K5-specific, C-terminal domain	C-terminal	High	Text match	14 proteins / 14 hits
IPR006626	Unmapped	-	557	578	InterPro	Parallel beta-helix repeat	-	-	-	-

Tail Spike Domain Segmentation

This protein has been segmented into three structural domains: N-terminal, central domain, and C-terminal.

Domain Layout

N-terminal

Central

C-terminal

A0AAF0D7Y3

1 613

Domain	Start	End	Length (AA)	Confidence
N-terminal	1	48	48	0,9575
Central domain	49	516	469	0,9958
C-terminal	517	613	96	0,9863

Legend: N-terminal Central domain C-terminal

3D Structure with Domain Coloring

The structure is colored according to the domain segmentation: N-terminal (blue), Central (green), C-terminal (pink).

Domain Coloring

N-terminal
1-48

Central
49-516

C-terminal
517-613

Taxonomy

	Name	Taxonomy ID	Lineage
Phage	Klebsiella phage Whistle [NCBI]	3018531	Uroviricota > Caudoviricetes > Autographivirales > Studiervirinae > Przondovirus
Host	Klebsiella variicola [NCBI]	244366	cellular organisms > Bacteria > Pseudomonadati > Pseudomonadota > Gammaproteobacteria > Enterobacterales

Coding sequence (CDS)

Genbank protein accession

WEU80649.1 [NCBI]

Genbank nucleotide accession

OQ579032 [NCBI]

CDS location

range 35307 -> 37148
strand +

CDS

ATGATAAAGACCGATTTTAACCAGCCGAAAGGCTCAACAATTGGTGTGCTCAAGGATGGGCGCACCGTCCAGCAGGCATTCGACCAATCGGTCTACGTGCCTATCGAGCAGTTCGGGGCCAAGGGTGACGGTATCTCGGATGACACCGCAGCGCTTCAGTTGGCACTGTCCAGTGGTAAGAACCTCTCGTTGTACGGGACGTATTTGGTAAAATCAACCCTATCGATTACCAAAGATGGACAGAAACTGGCGGGGTCTGGTACGCTCAAAATCGACGTTGCGGCTACGACTTTATTAAAGTCATTAGGTGCGTCTAACGTTAGAATTGAGGGGATTACGTTACAAAGCTCCTCAGCTGATACCAACACCTACAATGGCTCCTGCATCTGGGCAGAGAACTGCTCAGGTTGGGTTATCTCTGGGTGCCTATTCCGTGACTACAAAGCGTCGGCTGTGTTCATTAACAAGTCGTCTAACTTCAGGGTGACACATAACACCTTTCGTGGTGCTGCTGGTGCTGCTGGTGATGTGACAATGTGGCGCTCATGCTCTGGCAACCTTGTGAGTGCCAACGATATGACCTCAGGGTCGGACACAGCGATAGTCCTTCAGACAATTGAAGATGGTGACGTTTCTGTGGACAACATGATATCGTTCAACAGGATAGCGAATTGTACGCGTTACGGTATAGTCGTATATAACAGTTTGGAGCGCAAGGTTGGCTCTCTTCTGAGGACGCGTATAATCGGCAACAGTATAGACACCATCCATGGCTCGGTTACCAACCCGTCAGCTGGCAACGCTAAGACCTATGGGGCTGGCATCTACGTCCTATCGGCAGAGGGCATTGTTGTAAGCGACAACGTTGTCAGTCGGTGCAACCTAGAGACGAACTCGTCTACTCTGTCTCCTGGCTGCATCGGGGTAAACGCTACATCTAGCGCAATCATCTCTAATAACGCAGTTTCTGGTGGTGGGTATCATGGTATATTCATCTCTGACGCGTTGCAGCAGGGTGCTGGTAATTCTGCTGGAAGTGCTGCCTATAGACCAATCGGCGGAGTAGTGCTGTCTGGGAATACGGCAACCAGCTGTGTTCGTGACGGTATTCACATCGAGAACAAACACTCGGTCAAACTTATTGGTAACACCTGCACCCACAACTCTGGGAACGGTGTGGTAGTCTACACTACAAGCGGTGGGGTCAACTACCCGTCGATGGTAGACATCGCTGTACTGTCATGCACAAGTCTACGCAACGGACTAGCAGGACTCTCTCTGTCTAACTGTCAGTCACCTCAGGCCATTGGTGGCTCCTTCTCTTGGAACTCTGGCGATGGCGTGTCCACAAGTAGCCCAGCGAGCGTGTTGTCAAACCTCATGACTGAAGGAAACTCTCGTGGTATCGTGATGTCGGCGGCAGCGCTGAACTGCTCGGTGACCTTGTGTCGGGTGAATGGTAACGCCACAGGACTCGTGGCATTCTCTCCGTACTTGTTCGACAACAACAGCATCAATGGGAACACCACCGACTTTAATGGAAACTATGGACCTGTGAAGAACCTCACTGGCTCCTCGACTCCATCTGCAAAGTTCGTTAAGGTTATAACGTTGGGTGATGCCACTACGATAACTGATCTTCTCGATGGGGAGCTGGGTCAGACTGTGGTAATTCGTGCAGCTGCAAATGGGACAACTATTACACACAACACCAACTCAATTCGCTTGAATGGTAGTGTAGACTTTGTCATGCAAGCTGGCGACACCCTTACCTTGACTAAGTTCTTCCAGAACCAGTGGGATGAGGTCAGTAGGATGACGCGGGCAGTGGTGACATCATAA

Genome Context

Gene Ontology

	Description	Category	Evidence (source)
GO:0098015	virus tail	Cellular Component	IEA:UniProtKB-KW (UniProt)
GO:0098671	adhesion receptor-mediated virion attachment to host cell	Biological Process	IEA:UniProtKB-KW (UniProt)
GO:0098994	symbiont entry into host cell via disruption of host cell envelope	Biological Process	IEA:UniProtKB-KW (UniProt)
GO:0098996	symbiont entry into host cell via disruption of host cell glycocalyx	Biological Process	IEA:UniProtKB-KW (UniProt)

Tertiary structure

PDB ID

9608ab424ad17fb1c2bd8a4b9469b096ac2efe233ace3ff710a66cb60cbdd9f3

ESMFold

Source ESMFold

Method ESMFold

Resolution 0,8846

Oligomeric State monomer

Download PDB

Model Confidence

Very high
pLDDT > 90

High
90 > pLDDT > 70

Low
70 > pLDDT > 50

Very low
pLDDT < 50

Protein

Domains

Domains [InterPro]

Domains [InterPro]

Tail Spike Domain Segmentation

Tail Spike Domain Segmentation

3D Structure with Domain Coloring

Domain Coloring

Taxonomy

Coding sequence (CDS)

Coding sequence (CDS)

Genome Context

Genome Context

Gene Ontology

Tertiary structure

Predicted Aligned Error (PAE)

Model Confidence