Protein

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Genbank accession
UPW36204.1 [GenBank]
Protein name
tailspike protein
RBP type
TSP
Evidence DepoScope
Probability 1,00
TSP
Evidence RBPdetect
Probability 0,91
TSP
Evidence RBPdetect2
Probability 0,95
Protein sequence
MANKPTKPNFPLGLESQDQSVFQEGILNNGVVEHGPDAVMTVPETPDASGVPSAVRYNEDDDQFEGYYNEGGWLPLGGGNGGRWELLPYASSTLLQAGRAYLVDNTDGVSTVLFPSPKRIGDSVTVCDLYGKFSTYPLTVDGNGKSIYGSADSMTISTDNVSATFTWTGEARGWVITSGVGLGQGRVYSREIYSQILSATTPSIILSTQPSIVDVYVDGKRLKESLYTLDGYEVKFDPALASDSDVQIIQYIPIQLGAGGGGSGGTVITWEYNGGSAIGGETQIVLDVVVDSVSEIYIRGQRQQIGRGFTFDAATSTITLADELETGDDVVVIINGDPTVYNQIDRTPWEVARANNVSNAEVILSTDKQTALDGKTILYDVVTQISWGVPEGVPVGAKISNVSSGVLTYNPGGISVNLLELVNRKNIRELWKRSLAELDVTLVAGSFEEGGTVTNAKEALWFQAAGICYTWGGTFNKSVAAKSTPASTGGVNPASWSPVTDSLYSMLSAASGAALIGGLSFVNPQMFGGVGSTTIDNTDAVQAAAAAAEARGCELNLIGGPWRITKTIDMTNIRRVSTDISGRFLVDPTNFTAKHTNGYVITWGNPDTAYGTERCNHNVLVGTLLVTADNRTNSLHGIFVKGALLNFGAMRAVGFNGFGIRLGATWDSTFLSLSTELCGNTTDYALSVDPFGDTSNCLNIGRIQCERAYHKQMRINVIRSEIHNIHAERMYILTLNDGATSLPSGLTYENSYFLLSNSAVYQGVIDALESSAIGTVTTTPSVRLSLYASSAVALGLGTCIVTTTYGQTSTIDSTTFYKYYNPGYPVTLTSCRMISTETNDGLALLGGSGITMINCVMDIIQPDYSTSKLVLRGCTINRDLSNTRTGVSGVLFDACVFGGSIRETGPTDSNEPMKFLNCTIKGTFVGSYQHRCVMEGGWVASINLASRSFAKFINVRSASFNYTGDRGFITRGCEIENVIAWGTPGFGSYKVGERTQRCGAMVSGNGIEFINTTNNGASFVAITSLP
Physico‐chemical
properties
protein length:1026 AA
molecular weight: 109356,30760 Da
isoelectric point:4,84947
aromaticity:0,08772
hydropathy:-0,03470

Domains

Domains [InterPro]
DC_0041
STR
1–632
DC_0041
G3DSA:3.30.2020.50
ATT
342–426
G3DSA:3.30.2020.50 G3DSA:2.10.10.80 DC_1269
IPR040775
RBD
442–501
IPR040775
UPW36204.1
1 1026
Architecture
STR
ATT
STR
ATT
STR
STR 1-341 | ATT 342-426 | STR 427-439 | ATT 440-509 | STR 510-1005 |
Legend: ATT STR RBD CBM LEC ENZ CHP LNK TAS TTP UNK Unmapped

Tail Spike Domain Segmentation

Tail Spike Domain Segmentation

This protein has been segmented into three structural domains: N-terminal, central domain, and C-terminal.

Domain Layout
N-terminal
Central
C-terminal
UPW36204.1
1 1026
Domain Start End Length (AA) Confidence
N-terminal 1 534 534 0,9960
Central domain 535 971 438 0,9920
C-terminal 972 1026 54 0,9709
Legend: N-terminal Central domain C-terminal
3D Structure with Domain Coloring

The structure is colored according to the domain segmentation: N-terminal (blue), Central (green), C-terminal (pink).

Domain Coloring
N-terminal
1-534
Central
535-971
C-terminal
972-1026

Taxonomy

  Name Taxonomy ID Lineage
Phage Klebsiella phage K751
[NCBI] 		2930395 Viruses > Duplodnaviria > Heunggongvirae > Uroviricota > Caudoviricetes
Host Klebsiella pneumoniae
[NCBI] 		573 cellular organisms > Bacteria > Pseudomonadati > Pseudomonadota > Gammaproteobacteria > Enterobacterales

Coding sequence (CDS)

Coding sequence (CDS)
Genbank protein accession
UPW36204.1 [NCBI]
Genbank nucleotide accession
ON202820 [NCBI]
CDS location
range 149128 -> 152208
strand +
CDS
ATGGCTAATAAACCCACGAAACCAAATTTTCCGCTTGGGCTTGAATCACAAGATCAATCCGTATTTCAAGAAGGTATTCTGAATAATGGTGTTGTAGAACATGGCCCAGATGCGGTAATGACTGTGCCAGAAACTCCTGACGCATCTGGGGTTCCTTCTGCTGTCCGTTATAACGAAGACGACGATCAATTCGAAGGCTACTACAACGAAGGCGGCTGGTTGCCGCTTGGTGGCGGTAACGGTGGGCGCTGGGAACTCCTTCCGTATGCCTCCTCTACCCTGTTACAAGCAGGACGTGCATATCTGGTAGATAATACGGACGGCGTCTCTACGGTGCTGTTCCCTTCCCCTAAACGTATTGGTGACAGTGTTACTGTCTGTGACCTTTATGGTAAATTTTCCACTTATCCTCTGACTGTTGACGGTAACGGTAAATCGATCTATGGCTCTGCTGATAGCATGACGATTTCTACCGATAATGTCAGTGCGACTTTCACATGGACTGGTGAAGCCCGTGGCTGGGTTATTACATCAGGCGTCGGTCTGGGGCAAGGCCGGGTTTATAGCCGCGAAATTTACAGCCAAATTTTGTCAGCGACAACACCATCTATTATCCTGAGCACTCAACCATCTATTGTAGATGTGTACGTTGATGGAAAACGTTTGAAAGAATCCCTGTATACTCTCGACGGGTATGAAGTCAAATTCGATCCGGCGTTGGCCTCTGATTCTGATGTGCAGATTATTCAGTACATCCCAATTCAGCTCGGCGCGGGCGGTGGGGGTTCTGGTGGTACTGTGATCACCTGGGAATACAACGGTGGTTCAGCTATCGGCGGCGAAACCCAAATCGTGTTGGATGTGGTAGTGGACTCAGTATCTGAAATCTATATTCGCGGCCAGCGTCAACAAATAGGGCGCGGATTTACATTTGATGCAGCAACTAGCACAATCACACTTGCTGATGAGTTGGAAACAGGTGATGATGTCGTCGTTATTATTAACGGTGATCCCACGGTTTACAACCAAATAGATCGCACTCCTTGGGAAGTCGCCCGCGCGAATAATGTAAGCAATGCCGAAGTTATTCTCAGCACCGACAAGCAAACTGCGTTGGATGGCAAAACAATTCTTTATGATGTGGTAACTCAGATTAGTTGGGGTGTTCCAGAAGGTGTTCCGGTCGGAGCAAAGATTTCTAACGTTTCTTCTGGTGTTTTGACCTACAACCCTGGTGGTATCAGTGTTAACCTTCTTGAACTCGTAAACCGAAAGAACATTCGTGAGTTGTGGAAGCGTTCCCTCGCTGAATTGGATGTGACTCTCGTGGCGGGTAGTTTTGAAGAAGGCGGCACTGTCACCAACGCGAAAGAAGCGCTGTGGTTTCAGGCGGCGGGTATCTGCTATACTTGGGGTGGCACGTTTAATAAATCTGTCGCGGCCAAATCTACTCCGGCGAGCACTGGCGGCGTTAACCCGGCGTCGTGGTCTCCAGTCACTGATTCTCTCTATAGCATGTTGTCAGCAGCTTCTGGGGCAGCACTTATCGGTGGATTATCTTTCGTGAATCCACAGATGTTTGGTGGTGTCGGCAGCACGACGATTGATAACACTGATGCTGTTCAGGCTGCTGCCGCAGCAGCTGAAGCCCGTGGTTGTGAGTTGAATCTCATCGGTGGTCCTTGGAGAATTACCAAAACCATTGATATGACGAATATTCGCCGGGTGAGCACTGATATCTCTGGACGTTTCTTGGTTGATCCAACGAACTTCACGGCCAAGCACACCAACGGTTATGTTATCACTTGGGGCAACCCAGACACTGCTTATGGAACTGAACGTTGCAACCATAACGTCCTGGTGGGAACACTGTTGGTTACTGCTGACAATCGCACAAATTCTCTTCACGGCATTTTCGTCAAAGGCGCTCTGTTAAACTTTGGTGCAATGCGCGCTGTGGGTTTCAACGGTTTCGGCATTCGGCTTGGGGCGACTTGGGATTCTACGTTCCTGAGTTTGTCTACTGAACTTTGTGGTAACACGACTGACTATGCTCTGTCGGTAGATCCGTTTGGTGACACATCAAACTGTCTGAATATCGGTCGTATTCAATGCGAACGAGCATACCACAAACAGATGCGTATCAACGTTATCCGTTCGGAAATCCATAATATTCACGCAGAACGCATGTATATTTTGACTCTCAACGATGGCGCCACCAGTCTGCCGTCTGGTCTGACTTACGAAAACAGTTATTTCCTGTTGAGTAACTCTGCCGTCTATCAAGGGGTGATTGATGCCCTTGAAAGTTCTGCAATCGGCACAGTGACGACTACACCTTCCGTCCGACTGAGTCTCTATGCTTCCTCGGCGGTGGCTCTCGGTTTGGGTACTTGTATTGTCACTACAACCTATGGCCAGACTTCTACGATTGATAGTACCACGTTCTACAAATATTACAACCCTGGCTATCCGGTAACGTTAACATCTTGCCGAATGATTTCTACAGAAACAAATGATGGTCTGGCGTTGTTAGGTGGTTCCGGTATCACGATGATCAACTGCGTTATGGATATTATCCAGCCAGATTATTCGACCTCGAAATTGGTTCTAAGAGGGTGTACCATCAACAGAGATTTGTCAAACACTCGTACTGGCGTATCTGGTGTTCTGTTTGACGCATGTGTGTTTGGAGGCAGCATTCGTGAAACTGGTCCGACAGATTCCAATGAGCCGATGAAGTTCTTGAACTGTACGATCAAAGGCACGTTTGTTGGTTCGTACCAACACCGTTGTGTGATGGAAGGTGGGTGGGTGGCATCAATCAATTTGGCAAGTCGTTCATTCGCTAAATTCATTAATGTGCGGAGCGCCTCCTTCAACTACACAGGCGACCGTGGGTTTATAACCAGAGGCTGTGAGATTGAAAACGTTATAGCATGGGGAACTCCAGGGTTCGGTTCATACAAAGTCGGTGAGCGTACACAACGTTGTGGTGCAATGGTGAGCGGTAACGGTATCGAATTTATCAATACCACCAACAACGGTGCATCATTCGTGGCGATAACCAGTTTACCATAA

Genome Context

Genome Context

Tertiary structure

PDB ID
1c260e5cf5ec3e16a48f372687d938b87ebec1b4e450c6b6ee64de6f31a55a31
ESMFold
Source ESMFold
Method ESMFold
Resolution 0,6667
Oligomeric State monomer
Download PDB
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50

Literature

Title Authors Date PMID Source
Phenotypic and genotypic characterization of lytic phages against Klebsiella pneumoniae resistant to carbapenems Nolivos,K.V., Cabezas-Mera,F.S., Tisalema,E.E., Reyes,J.A., Fierro,I.M. and Pazmino,L.A. 2023-06-01 — GenBank