Protein

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UniProt accession

I6SN53 [UniProt]

Protein name

Pre neck appendage protein

RBP type

TSP

Evidence DepoScope

Probability 1,00

TSP

Evidence RBPdetect

Probability 0,90

TSP

Evidence RBPdetect2

Probability 0,93

Protein sequence

MKLDNLITKLHSYFSQKFVSQLENNFEQIKYWTNKSDDSFNEHLTTQKNAHTTDQIKHKTTKGKDVVLSNHENYQDELIEHLVLGHNGDGNNELKASHTSMDAQSFDSLHQRLYHDFLRESNAREELRADLTKKIQRIVNVDDFGGDPTGQKDSTKAFQDALGNGNVQVTMSGGTYLTTGIKMPNNSRLVGQGKDITTIKFMDETPAENIGITNLKMSGGAENISLESFSFNGNKFRQNKTLKATGGSRSSNIRFAGVTNGYIYNVKSYDALLHCIDVTYANDNYYYEGDGNRVPYALESKHIHIDNCEVYGCGDDGITTHHSRYITISNCYAHTPTGGSNNNGVEIDDGSQYVFLSNNRTKGNFGGLEIKAHSNASAASGVFVNGHVSIEDTRAYNIRHIGHHRAKTDNKSLTAYDVVLNNCLALNPKYNGVYPGSTPRALLISAYKNVSVNNFTAIGDDDFGKLEGGKLDKKQPAIAIQFMSENISLNNINVRNFKNAEVDIRLFGGDNRPSRVILNNINIWNSSNNIGIGVGSKIYDTKITNCNLHGNGSGIGLRLTNNHAMISGITANNYSTPAWIAGEKYDTPPTVGKGGASIASTGSAGVANASAVIASTGGSKAYSNRSFVLGSGANSKSYGSRSGIINSLNSETDKSGHTQLILNSNRVKSPGNYHVVAGYGSSGNASTSNIKFDLSTYSGNLTLAGQLKQDSADIAELFESQNGLAIDLGTIVTLDGDKIRKAQPNDTPIGVISGTAALVANEKTFHHKDRFLKNEYGVTITNRKQVEFVDDEGNVSFEWRDIPVENPEYNDKIDYQSRSERPEWNVVGLLGQIYTNIEKDVIPGDYINGRAGVGYKDNVNGKGRVMKITSEYTEERGCAIALVLWGAK

Physico‐chemical properties

protein length:	888 AA
molecular weight:	96899,07450 Da
isoelectric point:	6,62796
aromaticity:	0,07995
hydropathy:	-0,55203

Domains

Domains [InterPro]

DC_0125
ATT
1–265

DC_0125 IPR006626 IPR006626 IPR006626 IPR006626 IPR006626 IPR006626 G3DSA:2.160.10.20 G3DSA:2.40.300.10

IPR012334
STR
122–589

IPR012334 IPR021865

IPR011050
STR
133–527

IPR011050 G3DSA:4.10.80.40

IPR024535
ENZ
138–367

IPR024535 DC_0616

IPR006626
Unmapped
258–280

IPR006626

I6SN53

1 888

Architecture

ATT

STR

RBD

ATT 1-265 | STR 266-659 | RBD 660-884 |

Legend: ATT STR RBD CBM LEC ENZ CHP LNK TAS TTP UNK Unmapped

Domains [InterPro]

Domain ID	Category	Cluster	Start	End	Layer	Name	Pref Zone	Confidence	Evidence	Support
DC_0125	ATT	DC_0125	1	265	Novel HMM	DC_0125	N-terminal	Low	Positional only	68 proteins / 68 hits
IPR012334	STR	IPR012334	122	589	Merged direct domain	Pectin lyase fold	Central	Low	Positional only	867 proteins / 867 hits
IPR011050	STR	IPR011050	133	527	Merged direct domain	Pectin lyase fold/virulence factor	Central	Low	Positional only	572 proteins / 572 hits
IPR024535	ENZ	DC_0410	138	367	InterPro cluster	Rhamnogalacturonase A/B/Epimerase-like, pectate lyase domain	Central	High	Text match	420 proteins / 426 hits
IPR006626	Unmapped	-	258	280	InterPro	Parallel beta-helix repeat	-	-	-	-
IPR006626	Unmapped	-	300	322	InterPro	Parallel beta-helix repeat	-	-	-	-
IPR006626	Unmapped	-	323	349	InterPro	Parallel beta-helix repeat	-	-	-	-
IPR006626	Unmapped	-	351	372	InterPro	Parallel beta-helix repeat	-	-	-	-
DC_0616	STR	DC_0616	368	659	Novel HMM	DC_0616	Central	Low	Positional only	58 proteins / 58 hits
IPR006626	Unmapped	-	415	437	InterPro	Parallel beta-helix repeat	-	-	-	-
IPR006626	Unmapped	-	513	536	InterPro	Parallel beta-helix repeat	-	-	-	-
IPR006626	Unmapped	-	538	559	InterPro	Parallel beta-helix repeat	-	-	-	-
G3DSA:2.160.10.20	RBD	G3DSA:2.160.10.20	590	707	Merged direct domain	G3DSA:2.160.10.20	C-terminal	Low	Positional only	6 proteins / 6 hits
IPR021865	CHP	DC_0580	659	884	InterPro cluster	Peptidase G2, IMC autoproteolytic cleavage domain	C-terminal	High	Text match	84 proteins / 84 hits
G3DSA:2.40.300.10	RBD	G3DSA:2.40.300.10	713	884	Merged direct domain	G3DSA:2.40.300.10	C-terminal	Low	Positional only	19 proteins / 19 hits
G3DSA:4.10.80.40	RBD	G3DSA:4.10.80.40	766	813	Merged direct domain	G3DSA:4.10.80.40	C-terminal	Low	Positional only	3 proteins / 3 hits

Tail Spike Domain Segmentation

This protein has been segmented into three structural domains: N-terminal, central domain, and C-terminal.

Domain Layout

N-terminal

Central

C-terminal

I6SN53

1 888

Domain	Start	End	Length (AA)	Confidence
N-terminal	1	153	153	0,9926
Central domain	154	615	463	0,9829
C-terminal	616	888	272	0,8363

Legend: N-terminal Central domain C-terminal

3D Structure with Domain Coloring

The structure is colored according to the domain segmentation: N-terminal (blue), Central (green), C-terminal (pink).

Domain Coloring

N-terminal
1-153

Central
154-615

C-terminal
616-888

Taxonomy

	Name	Taxonomy ID	Lineage
Phage	Staphylococcus phage vB_SepiS-phiIPLA7 [NCBI]	2922989	Uroviricota > Caudoviricetes > Rockefellervirus >
Host	Staphylococcus epidermidis [NCBI]	1282	cellular organisms > Bacteria > Bacillati > Bacillota > Bacilli > Bacillales

Coding sequence (CDS)

No CDS data available.

Genome Context

Gene Ontology

	Description	Category	Evidence (source)
GO:0044423	virion component	Cellular Component	IEA:UniProtKB-KW (UniProt)
GO:0051701	biological process involved in interaction with host	Biological Process	IEA:UniProtKB-ARBA (UniProt)
GO:0019058	viral life cycle	Biological Process	IEA:UniProtKB-ARBA (UniProt)

Tertiary structure

PDB ID

a2ea2ee82eeb2749f70c65ff4c3b9efe0df68c973b77ec500d500e213b80fa4b

ESMFold

Source ESMFold

Method ESMFold

Resolution 0,7900

Oligomeric State monomer

Download PDB

Model Confidence

Very high
pLDDT > 90

High
90 > pLDDT > 70

Low
70 > pLDDT > 50

Very low
pLDDT < 50

Protein

Domains

Domains [InterPro]

Domains [InterPro]

Tail Spike Domain Segmentation

Tail Spike Domain Segmentation

3D Structure with Domain Coloring

Domain Coloring

Taxonomy

Coding sequence (CDS)

Coding sequence (CDS)

Genome Context

Genome Context

Gene Ontology

Tertiary structure

Predicted Aligned Error (PAE)

Model Confidence