Protein

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UniProt accession

U5PWB9 [UniProt]

Protein name

Endolysin

RBP type

Evidence Phold

Probability 1,00

Evidence RBPdetect

Probability 0,86

Protein sequence

MFGGGRSEKDIAAGRFDCSSYVRWAYSQLGINLGPLTSTSTETLKNKGTAVKGGIKNAQPGDLLFFDTYKKNGHVVIYLGNNQFIGAQGKTGVGIVDMNSSYGKYFTKRFSGNIRRIAGGGNVGAALGGGGAAMSGAGTGTAYRQAPSNLMGPINNAAKQYGVNPNLIAAIIKKESTFKSGLTSSAGAKGYMQLMPATARAMGVKNPWDTQQNINGGTKYIAQQLKTYKNNIPLALAAYNWGPGNLNKAIRKAGGSKDWNQIRRFAPKETRDYVDKIMGWR

Physico‐chemical properties

protein length:	281 AA
molecular weight:	29955,74800 Da
isoelectric point:	10,16049
aromaticity:	0,09609
hydropathy:	-0,43238

Domains

Domains [InterPro]

IPR000064
ENZ
1–117

IPR000064 IPR023346

G3DSA:3.90.1720.10
RBD
2–120

G3DSA:3.90.1720.10 PTHR37423

IPR000064
ENZ
3–107

IPR000064 G3DSA:1.10.530.10

IPR038765
STR
14–116

IPR038765 IPR008258

G3DSA:1.10.530.10
RBD
160–281

G3DSA:1.10.530.10

cd00254
ENZ
165–279

cd00254

U5PWB9

1 281

Architecture

RBD

STR

RBD 1-13 | STR 14-120 | STR 144-281

Legend: ATT STR RBD CBM LEC ENZ CHP LNK TAS TTP UNK Unmapped

Domains [InterPro]

Domain ID	Category	Cluster	Start	End	Layer	Name	Pref Zone	Confidence	Evidence	Support
IPR000064	ENZ	DC_0076	1	117	InterPro cluster	Endopeptidase, NLPC/P60 domain	Central	High	Text match	22 proteins / 43 hits
G3DSA:3.90.1720.10	RBD	G3DSA:3.90.1720.10	2	120	Merged direct domain	G3DSA:3.90.1720.10	C-terminal	Low	Positional only	22 proteins / 22 hits
IPR000064	ENZ	DC_0076	3	107	InterPro cluster	Endopeptidase, NLPC/P60 domain	Central	High	Text match	22 proteins / 43 hits
IPR038765	STR	IPR038765	14	116	Merged direct domain	Papain-like cysteine peptidase superfamily	Central	Low	Positional only	7 proteins / 7 hits
IPR023346	STR	IPR023346	144	279	Merged direct domain	Lysozyme-like domain superfamily	Central	Low	Positional only	29 proteins / 29 hits
PTHR37423	Unmapped	-	145	279	PANTHER	SOLUBLE LYTIC MUREIN TRANSGLYCOSYLASE-RELATED	-	-	-	-
G3DSA:1.10.530.10	RBD	G3DSA:1.10.530.10	145	281	Merged direct domain	G3DSA:1.10.530.10	C-terminal	Low	Positional only	95 proteins / 95 hits
IPR008258	ENZ	DC_0010	154	261	InterPro cluster	Transglycosylase SLT domain 1	C-terminal	High	Text match	100 proteins / 142 hits
G3DSA:1.10.530.10	RBD	G3DSA:1.10.530.10	160	281	Merged direct domain	G3DSA:1.10.530.10	C-terminal	Low	Positional only	95 proteins / 95 hits
cd00254	ENZ	DC_0010	165	279	InterPro cluster	cd00254	C-terminal	High	Text match	100 proteins / 142 hits

Taxonomy

	Name	Taxonomy ID	Lineage
Phage	Bacillus phage poppyseed [NCBI]	1406787	Viruses > Duplodnaviria > Heunggongvirae > Uroviricota > Caudoviricetes
Host	Bacillus megaterium [NCBI]	1404	cellular organisms > Bacteria > Bacillati > Bacillota > Bacilli > Bacillales

Coding sequence (CDS)

No CDS data available.

Genome Context

Gene Ontology

	Description	Category	Evidence (source)
GO:0008234	cysteine-type peptidase activity	Molecular Function	IEA:UniProtKB-KW (UniProt)
GO:0006508	proteolysis	Biological Process	IEA:UniProtKB-KW (UniProt)
GO:0001897	symbiont-mediated cytolysis of host cell	Biological Process	IEA:UniProtKB-ARBA (UniProt)

Tertiary structure

PDB ID

ddba26970301728bafc244439b554a6fce04a98860a554e1c496f3ba1ef57206

ESMFold

Source ESMFold

Method ESMFold

Resolution 0,8949

Oligomeric State monomer

Download PDB

Model Confidence

Very high
pLDDT > 90

High
90 > pLDDT > 70

Low
70 > pLDDT > 50

Very low
pLDDT < 50

Protein

Domains

Domains [InterPro]

Domains [InterPro]

Taxonomy

Coding sequence (CDS)

Coding sequence (CDS)

Genome Context

Genome Context

Gene Ontology

Tertiary structure

Predicted Aligned Error (PAE)

Model Confidence