Protein

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Genbank accession

APD22650.1 [GenBank]

Protein name

hyaluronidase

RBP type

Evidence RBPdetect2

Probability 0,72

Protein sequence

MLYLLNKDVRTVRWNGDPLHEVTSAIVKEIMNGDFTLTVKYPISDSGIYQLIQEDMLIKAPTPVLGAHLFRIKKPVEYNDHLEITAYHISDDVMQRSITPVSVTSQSCGMTLSRMVQNTKTALGDFSFNSDIQDRRTFNTTETETLYSILLDGKHSIVGTWGGELVRDNFAMTVKKSRGENRGVVITTHKNLKNYQRTKNSQNVVTRIHAKSTFKPEGAEKETTIRVTVDSPLINSYPYINEKEYENNNAKTVEELQKWAQSKFSNEGIDKVSDAIKIQAYELDGQVVHMGDTVNLKSWKHNVDAFKKAIAYEFDALKEEYISLTFDDKAGIGGSRASGGLSSAADAILGVTESAQEIALEKALQNADLDFDHKAGLLRQEISDDIELAKARAEEVKRELSDTINQRFNSFDNGPLKETKRKAEEALRNAGASSSLAQESKRIGLDSVARLEAFKSQTTSAQTALSGDLDALKRTIANDIRPKQAQAEAEIAKQVEALSRTKNELAGASSSLAQESKRIGLDSVARLEAFKSQTTSAQTALSGDLDALKRTIANDIRPKQAQAEAEIAKQVEALSRTKNELDGASTLLAQEAKRIELDSVARLEAFKSQTTSAQTALSGDLDVLKRTIANDIRPKQAQAEAEIAKQVEALSRTKNELAGVKSAQATYEETTTRRLSELTNLANGKASKSELTQTAEELASRIASVQASGRNLFLNSLFKQDISKTGIWTTSTYTATIDSESKYLGYNALKIIGLNPSGRDGGNPKVTYPVLGQFGKVIPGSTTNQDVTISFYAKANKNGIMLRSRLGNIGYKTGNVTLSTEIKRYVVHIPKGWTNESKQTTNEWLFNFNQEGTVWIWMPKFEISDVDTSYSEAPEDIEGQISTVESTFKQRVNSLEAGVNRLTEGLRTKVDISALNVTAENIRQSVKSLETDTQNKLNQKLSQAEFEVRAGSIRQEILNATKDKADKTLVVSEAGKLREEFSKMKVGGRNLWIKSKTVGAVIEKLPENHVTGQKECYRLENNSTLTFNLEPDFSSRLYQKVTFSAWIKYENVVQGRNFWNVFNCFKHYLFRKNSETGVQSGPDYATLGMYKGSADWKYITFTYDYSEKTNFDQLKTSLRFNLEGATSGTAWVTGIKVEIGSVATDWSPAPEDGENELLVAKTEFKRTADGLSTKMAAVESYVGQDGQRQEALQRYTREESARQATAVRELVNRDFVGKATYQEDVKGINQRIEAVKTSANKDIASQIASYRQSVDGKFTDISSQITTYKQDVGGQISGLSNRLTSSEQGTTTQISNLSNRINSNKQGADNQISNLKTQVATNKDNAERQMGRISDQVSANKANADSQFANVTNQLVRKVETTDFQRVKETSKLYERILGNTENGIADKVARMALTNQLFQVEVGKVAKGGRNYIRNGQFKNGSKNWLEYQSVNFGLNFNYQHSQNPNNRNRPGLHFYHDSQDVANFFGIQQSFAFEGVRGEKVSVSLLVSKDGSDSYSGLKVALHYIKNKNIIGQEWQNIPSPQITSKYKRFTFTFTLSDDVENLNLMLFGEKGKTINLYVTDVQLERGSVATDYKEAPEDTDEAIRSVQSQLTGSWAVQNINSAGDIISGINLGANGHNRFVGKLTHITGETLIDRAVIKSAMVDKLKTANFEAGSVTTTILDAEAVTAEKLKVDNALIRKLTANDAFIDQLTSKRIFSTKVESVISSSTFLEAYQGRIGGFTLGQFDQGGGRWISGVNQFSVGMGNGAGYGVRTAFWANWGNNWNYAGPKAWNVNTDGKMYCRNEVGFYDQVDFSNSSRANFYGNTTFSRSPVFSNGIELGSKDVLGDGWNPKGGRNAVVWWNQVGSGSVKYWMEQKSDRRLKENITDTAVKALDKINRLRMVAFDFIENKKHEEIGLIAQEAETIVPRIVSRDPENPDGYLHIDYTALVPYLIKAIQELNQKIEKMEKTIA

Physico‐chemical properties

protein length:	1954 AA
molecular weight:	216938,12120 Da
isoelectric point:	8,34435
aromaticity:	0,07881
hydropathy:	-0,54278

Domains

Domains [InterPro]

DC_1274
ATT
1–581

DC_1274 Coil Coil DC_0720 DC_0720

IPR007119
Unmapped
31–326

IPR007119 Coil Coil Coil Coil G3DSA:2.60.120.260 DC_0720 IPR008979 IPR030392

G3DSA:2.60.120.260
STR
1411–1574

G3DSA:2.60.120.260 IPR030392

DC_0976
RBD
1910–1954

DC_0976

APD22650.1

1 1954

Architecture

ATT

STR

RBD

ATT 1-581 | STR 734-1921 | RBD 1922-1954

Legend: ATT STR RBD CBM LEC ENZ CHP LNK TAS TTP UNK Unmapped

Domains [InterPro]

Domain ID	Category	Cluster	Start	End	Layer	Name	Pref Zone	Confidence	Evidence	Support
DC_1274	ATT	DC_1274	1	581	Novel HMM	DC_1274	N-terminal	Low	Positional only	124 proteins / 124 hits
IPR007119	Unmapped	-	31	326	InterPro	Phage tail spike protein, N-terminal domain	-	-	-	-
Coil	Unmapped	-	379	406	Coils	Coil	-	-	-	-
Coil	Unmapped	-	484	504	Coils	Coil	-	-	-	-
Coil	Unmapped	-	560	580	Coils	Coil	-	-	-	-
Coil	Unmapped	-	636	656	Coils	Coil	-	-	-	-
Coil	Unmapped	-	688	708	Coils	Coil	-	-	-	-
DC_0720	STR	DC_0720	734	1162	Novel HMM	DC_0720	Central	Low	Positional only	121 proteins / 121 hits
Coil	Unmapped	-	912	932	Coils	Coil	-	-	-	-
G3DSA:2.60.120.260	STR	G3DSA:2.60.120.260	973	1142	Merged direct domain	G3DSA:2.60.120.260	Central	Low	Positional only	264 proteins / 264 hits
DC_0720	STR	DC_0720	1153	1258	Novel HMM	DC_0720	Central	Low	Positional only	121 proteins / 121 hits
DC_0720	STR	DC_0720	1255	1921	Novel HMM	DC_0720	Central	Low	Positional only	121 proteins / 121 hits
IPR008979	STR	IPR008979	1410	1567	Merged direct domain	Galactose-binding-like domain superfamily	Central	Low	Positional only	24 proteins / 24 hits
G3DSA:2.60.120.260	STR	G3DSA:2.60.120.260	1411	1574	Merged direct domain	G3DSA:2.60.120.260	Central	Low	Positional only	264 proteins / 264 hits
IPR030392	CHP	DC_0088	1860	1913	InterPro cluster	Intramolecular chaperone auto-processing domain	C-terminal	High	Text match	3502 proteins / 3959 hits
IPR030392	CHP	DC_0088	1860	1953	InterPro cluster	Intramolecular chaperone auto-processing domain	C-terminal	High	Text match	3502 proteins / 3959 hits
DC_0976	RBD	DC_0976	1910	1954	Novel HMM	DC_0976	C-terminal	Low	Positional only	60 proteins / 60 hits

Taxonomy

	Name	Taxonomy ID	Lineage
Phage	Streptococcus phage IPP28 [NCBI]	1916168	Viruses > Duplodnaviria > Heunggongvirae > Uroviricota > Caudoviricetes
Host	Streptococcus pneumoniae GA41317 [NCBI]	760810	Bacillota > Bacilli > Lactobacillales > Streptococcaceae > Streptococcus > Streptococcus pneumoniae

Coding sequence (CDS)

Genbank protein accession

APD22650.1 [NCBI]

Genbank nucleotide accession

KY065469 [NCBI]

CDS location

range 24808 -> 30672
strand +

CDS

TTGCTTTATCTACTTAATAAAGATGTGAGAACCGTTCGGTGGAACGGGGATCCACTTCATGAAGTGACTTCGGCGATTGTTAAAGAGATCATGAATGGCGATTTCACCTTAACTGTGAAATATCCCATTTCCGACTCTGGTATTTATCAGCTCATCCAAGAAGATATGTTGATAAAAGCGCCGACTCCTGTTCTTGGTGCGCATCTATTTCGCATTAAGAAACCTGTTGAATACAATGATCATCTGGAAATCACAGCCTATCACATTTCAGACGATGTGATGCAACGTTCTATCACACCAGTAAGTGTGACTAGTCAGAGCTGTGGCATGACTCTTTCTCGCATGGTTCAAAACACCAAAACTGCTTTGGGAGATTTTTCTTTCAATAGCGATATCCAGGACCGTAGGACCTTCAATACGACTGAAACAGAAACCCTATACTCTATATTGCTGGACGGTAAGCACAGCATTGTTGGTACATGGGGAGGCGAGCTGGTTCGTGATAACTTTGCGATGACTGTCAAGAAGAGTCGTGGGGAGAATCGTGGTGTTGTTATTACAACGCACAAAAATCTGAAGAACTACCAACGCACAAAAAACAGTCAGAATGTTGTCACAAGAATTCACGCAAAGTCGACTTTTAAACCTGAAGGTGCTGAAAAAGAAACGACTATCAGAGTGACTGTTGATAGTCCTCTTATCAACTCATACCCTTATATCAATGAAAAAGAGTATGAGAACAACAATGCTAAAACTGTTGAAGAGTTGCAGAAGTGGGCACAGTCTAAGTTCTCAAATGAGGGAATTGACAAGGTCTCTGATGCTATCAAGATTCAAGCTTATGAACTTGATGGGCAAGTGGTCCATATGGGCGACACGGTCAATCTCAAGAGCTGGAAACATAATGTCGATGCATTCAAGAAAGCTATTGCTTATGAGTTCGATGCCTTAAAAGAAGAATACATCTCTCTGACTTTCGATGATAAGGCAGGTATTGGTGGTTCTAGAGCTTCTGGTGGCCTATCTAGCGCAGCCGATGCAATTCTTGGAGTGACAGAATCTGCACAAGAAATCGCCCTTGAAAAGGCTCTTCAAAATGCTGACTTAGACTTTGATCATAAGGCTGGATTGCTTAGACAGGAAATTTCTGACGATATTGAACTGGCCAAAGCCAGAGCTGAAGAAGTCAAGAGAGAACTGTCTGACACTATCAATCAGCGATTTAATAGCTTTGACAACGGGCCATTGAAAGAAACTAAGCGCAAGGCTGAGGAAGCTTTGCGAAATGCTGGCGCAAGTAGTTCTCTTGCTCAGGAATCCAAGCGGATTGGGCTGGATTCTGTTGCTAGACTTGAAGCGTTTAAGTCGCAGACTACGAGCGCACAAACGGCTCTGTCGGGTGACTTGGACGCTCTGAAACGGACTATCGCGAATGATATTCGACCGAAGCAAGCACAGGCTGAAGCTGAGATTGCCAAGCAAGTTGAAGCACTTAGCCGGACTAAAAATGAACTGGCTGGCGCAAGTAGTTCTCTTGCTCAGGAATCCAAGCGGATTGGGCTGGATTCTGTTGCTAGACTTGAAGCGTTTAAGTCGCAGACTACGAGCGCACAAACGGCTCTGTCGGGTGACTTGGACGCTCTGAAACGGACTATCGCGAATGATATTCGACCGAAGCAAGCACAGGCTGAAGCTGAGATTGCCAAGCAAGTTGAAGCACTTAGCCGGACTAAAAATGAACTGGATGGCGCAAGTACCCTGCTTGCACAGGAAGCTAAGCGGATTGAGCTGGATTCTGTTGCTAGACTTGAAGCGTTTAAGTCGCAGACTACGAGCGCACAAACGGCTCTGTCAGGTGACTTGGATGTTCTAAAACGAACTATCGCAAACGATATTCGACCGAAGCAAGCACAGGCTGAAGCTGAGATTGCCAAGCAAGTTGAAGCACTTAGCCGGACTAAAAATGAACTGGCTGGCGTGAAGTCAGCGCAAGCGACGTATGAGGAGACGACGACTCGTAGACTGTCAGAACTGACCAACTTGGCCAATGGTAAAGCCAGCAAGTCAGAACTCACGCAGACAGCTGAGGAGCTAGCTAGTCGGATTGCGAGTGTGCAGGCATCCGGTCGAAATCTATTCTTGAACTCACTATTCAAGCAGGATATTTCAAAAACAGGAATTTGGACAACGAGTACATATACGGCTACTATCGATAGCGAAAGTAAGTATCTTGGATATAACGCTCTTAAAATTATAGGTCTGAATCCATCTGGCCGTGATGGAGGGAATCCCAAGGTTACTTATCCAGTTCTGGGTCAATTCGGGAAAGTAATTCCCGGAAGTACGACTAATCAAGATGTAACCATTAGTTTTTATGCTAAGGCAAATAAAAATGGAATAATGCTAAGATCTCGATTAGGGAATATCGGATATAAAACTGGAAATGTGACATTGTCGACAGAAATTAAACGATATGTTGTCCATATTCCAAAAGGTTGGACAAACGAATCCAAGCAGACCACAAATGAATGGTTGTTCAATTTCAACCAGGAAGGAACCGTTTGGATTTGGATGCCGAAGTTTGAAATAAGCGATGTAGATACTTCTTATTCAGAAGCTCCTGAAGATATAGAAGGTCAGATTTCAACAGTTGAATCGACCTTTAAACAACGAGTCAACTCGCTCGAAGCTGGTGTGAATCGTCTGACTGAAGGCCTTAGAACCAAAGTGGATATCAGCGCACTCAACGTGACTGCTGAAAATATCCGGCAATCTGTGAAGAGTCTTGAGACAGACACGCAGAACAAGCTAAATCAGAAGTTGAGTCAGGCTGAATTTGAGGTGCGAGCCGGCTCTATCCGTCAGGAAATCCTGAACGCAACCAAGGATAAGGCAGATAAGACTTTAGTTGTATCTGAAGCTGGGAAATTGCGTGAAGAATTTTCAAAAATGAAGGTGGGAGGCCGGAATCTATGGATAAAATCCAAGACGGTTGGAGCTGTAATTGAAAAATTACCTGAAAACCATGTCACAGGTCAAAAAGAATGTTATAGGTTAGAGAACAACTCTACTTTAACGTTCAACCTTGAACCAGATTTCAGCTCAAGGTTGTATCAAAAAGTTACTTTTAGCGCTTGGATCAAGTACGAAAATGTAGTCCAAGGTCGAAACTTTTGGAATGTATTTAATTGCTTCAAACATTATCTTTTTAGAAAAAATAGTGAGACCGGAGTACAGAGTGGTCCAGATTATGCTACGCTTGGTATGTATAAAGGTTCGGCAGATTGGAAATATATTACATTCACTTATGACTACTCTGAAAAAACAAATTTTGATCAATTGAAGACATCATTGCGATTCAATCTTGAAGGTGCTACAAGCGGTACAGCTTGGGTAACAGGAATCAAGGTTGAAATCGGTAGTGTGGCGACGGACTGGTCACCAGCACCAGAAGACGGAGAAAATGAGCTTTTAGTCGCTAAAACCGAGTTCAAGAGGACAGCTGATGGCCTATCTACTAAGATGGCAGCAGTTGAGAGCTATGTTGGTCAAGACGGTCAGCGACAGGAAGCCCTACAGCGCTATACTCGTGAGGAAAGCGCGAGACAAGCGACAGCAGTCCGTGAGCTGGTCAATCGTGATTTCGTTGGTAAGGCTACTTATCAAGAAGATGTTAAGGGTATCAATCAAAGGATTGAAGCTGTTAAAACTAGTGCGAATAAAGACATCGCTAGTCAAATCGCTAGCTATCGTCAATCTGTAGATGGTAAGTTCACGGATATTTCAAGTCAGATAACTACTTATAAGCAAGATGTGGGCGGTCAAATCAGTGGCCTTTCAAATAGACTTACAAGCAGTGAGCAAGGAACCACTACTCAGATTTCAAATCTTTCAAATCGGATAAACAGTAATAAACAAGGCGCAGATAATCAGATTTCAAATTTAAAGACTCAGGTCGCTACAAACAAGGATAATGCTGAACGACAAATGGGTAGAATATCTGATCAGGTTTCTGCAAACAAAGCGAATGCTGATAGTCAATTTGCGAATGTGACCAATCAACTAGTGCGAAAAGTAGAGACTACTGACTTCCAGCGTGTTAAGGAAACCAGTAAACTTTACGAGCGGATTTTGGGCAATACTGAAAATGGAATTGCGGATAAGGTTGCTCGCATGGCTCTGACCAATCAACTGTTTCAGGTTGAGGTTGGGAAGGTTGCCAAAGGTGGTCGAAATTATATCAGAAATGGTCAATTTAAGAACGGTTCGAAAAACTGGCTTGAATATCAATCTGTTAATTTTGGTTTGAATTTCAACTATCAACACTCTCAAAATCCTAATAATCGAAATCGTCCAGGACTACACTTCTATCACGATTCTCAAGATGTTGCTAATTTTTTTGGAATTCAGCAATCTTTTGCTTTTGAAGGTGTTCGAGGAGAAAAAGTGAGTGTATCTCTTCTTGTTTCAAAGGATGGCAGTGATAGCTACAGCGGTTTGAAAGTTGCATTGCACTACATCAAAAACAAAAACATTATTGGGCAAGAGTGGCAAAATATCCCAAGTCCACAAATAACATCGAAGTATAAGCGTTTCACATTTACGTTTACTTTATCAGACGATGTAGAGAATCTGAATTTGATGTTGTTTGGTGAAAAAGGGAAGACCATCAACCTCTATGTTACAGATGTTCAACTCGAAAGAGGTTCTGTCGCGACGGATTACAAAGAAGCTCCTGAAGACACGGACGAAGCGATTCGCTCTGTTCAAAGCCAACTAACTGGCTCATGGGCAGTTCAAAACATCAACTCGGCTGGAGATATCATCTCTGGAATCAATCTTGGCGCCAATGGACATAACCGATTTGTTGGGAAATTGACCCACATCACTGGAGAGACCCTGATTGACAGAGCAGTCATCAAGTCTGCCATGGTTGATAAGCTCAAAACGGCCAATTTTGAAGCTGGTTCGGTCACGACTACGATATTAGACGCTGAAGCGGTAACTGCTGAGAAGTTGAAAGTTGACAATGCGCTTATTAGAAAATTAACTGCAAATGATGCTTTTATTGACCAACTGACATCTAAACGTATCTTCTCTACTAAGGTTGAGTCCGTCATTTCTAGTTCAACCTTCCTAGAAGCCTATCAAGGTCGAATTGGTGGATTCACACTTGGTCAATTTGACCAGGGTGGCGGTCGCTGGATTTCAGGTGTCAATCAGTTCTCTGTTGGTATGGGGAATGGTGCCGGGTATGGAGTCCGGACAGCCTTCTGGGCGAACTGGGGAAATAATTGGAACTATGCCGGACCTAAAGCATGGAACGTCAATACTGATGGGAAAATGTACTGTAGGAATGAAGTCGGTTTTTATGATCAAGTGGATTTTTCGAATTCATCGAGAGCAAACTTCTATGGGAATACTACTTTTTCTCGTTCTCCTGTGTTTTCAAATGGTATCGAACTTGGAAGTAAAGATGTGCTTGGTGATGGTTGGAATCCCAAAGGCGGAAGGAATGCGGTTGTTTGGTGGAATCAGGTCGGTAGCGGTAGCGTGAAGTATTGGATGGAACAAAAATCAGACAGACGCTTAAAAGAGAACATCACAGATACAGCTGTGAAAGCCTTGGATAAAATCAACAGATTAAGAATGGTTGCATTTGATTTCATCGAAAATAAGAAACATGAGGAGATTGGTCTAATAGCTCAAGAGGCTGAAACCATCGTTCCAAGAATTGTCTCACGAGATCCTGAGAATCCAGATGGCTATCTACATATCGACTATACCGCTTTAGTTCCTTACTTAATCAAGGCTATTCAAGAATTAAATCAAAAAATAGAAAAAATGGAGAAAACAATAGCATGA

Genome Context

Tertiary structure

PDB ID

87bbaa9c57c01a4061baa9c13e7fd9962d8152050de572e74fdf0e3924fb797e

ColabFold

Source ColabFold

Method ColabFold

Resolution 0,6243

Oligomeric State monomer

Download PDB

Model Confidence

Very high
pLDDT > 90

High
90 > pLDDT > 70

Low
70 > pLDDT > 50

Very low
pLDDT < 50

Protein

Domains

Domains [InterPro]

Domains [InterPro]

Taxonomy

Coding sequence (CDS)

Coding sequence (CDS)

Genome Context

Genome Context

Tertiary structure

Predicted Aligned Error (PAE)

Model Confidence