Protein

View in Explore

Genbank accession

QZI79674.1 [GenBank]

Protein name

tail spike protein

RBP type

Evidence Phold

Probability 1,00

TSP

Evidence DepoScope

Probability 1,00

TSP

Evidence RBPdetect

Probability 0,90

TSP

Evidence RBPdetect2

Probability 0,92

Protein sequence

MAKLTRVTDWLVKVKSRLTGAVERLLEDKLNDTVSVKDFGAKGDGVTDDTQAFAAASAASPQGVYVPDGTYLLPEDINGRFYGSGKRIKAVGDGGIPFTNVAQSHSNLILGYDAAKDYTDEGKGNQLVLLGPSSGRNLTTGTNSIVVGVGGLSGDTLEDALTDKSPFTGTEIISIGINALKKTTTGNNMIGIGRDALNECKDGRFNVAVGMSALQQLHSGEANVAIGRSAGMRTGIFTNEEGVRLGYTKCSGNTLIGNAAGRELKSGNHNTAVGNGAMRGVSSDINPYTGTLEGNFNTAIGVDTLNSLASGELNTMIGARAGRKLPSGSGNIFIGADAGAGINVEKSNTLIINNHTGLPFVEGIMGGAQSGNNYLRVDGSVAPQIDNTRTCGQSSRRWQTVFATNGVIQTSDGRCKDVYDIAKKEYMAGLELASSMIKFKWTDTEEDKYHFGCLAQEVMLIMEKHGLNPLDYSLVTYDAEADMYGVNYAELSCFCIAAMSNHVLGSA

Physico‐chemical properties

protein length:	507 AA
molecular weight:	53342,19620 Da
isoelectric point:	5,41684
aromaticity:	0,06312
hydropathy:	-0,20178

Domains

Domains [InterPro]

DC_1226
STR
2–499

DC_1226

IPR012334
STR
14–205

IPR012334 IPR044914 IPR036388

IPR011050
STR
31–84

IPR011050 IPR030392

IPR011050
STR
32–356

IPR011050

IPR024535
ENZ
34–149

IPR024535

QZI79674.1

1 507

Architecture

STR

STR 2-507

Legend: ATT STR RBD CBM LEC ENZ CHP LNK TAS TTP UNK Unmapped

Domains [InterPro]

Domain ID	Category	Cluster	Start	End	Layer	Name	Pref Zone	Confidence	Evidence	Support
DC_1226	STR	DC_1226	2	499	Novel HMM	DC_1226	Central	Low	Positional only	5 proteins / 5 hits
IPR012334	STR	IPR012334	14	205	Merged direct domain	Pectin lyase fold	Central	Low	Positional only	867 proteins / 867 hits
IPR011050	STR	IPR011050	31	84	Merged direct domain	Pectin lyase fold/virulence factor	Central	Low	Positional only	572 proteins / 572 hits
IPR011050	STR	IPR011050	32	356	Merged direct domain	Pectin lyase fold/virulence factor	Central	Low	Positional only	572 proteins / 572 hits
IPR024535	ENZ	DC_0410	34	149	InterPro cluster	Rhamnogalacturonase A/B/Epimerase-like, pectate lyase domain	Central	High	Text match	420 proteins / 426 hits
IPR044914	RBD	IPR044914	310	415	Merged direct domain	Endosialidase, C-terminal domain superfamily	C-terminal	Low	Positional only	39 proteins / 39 hits
IPR030392	CHP	DC_0088	411	507	InterPro cluster	Intramolecular chaperone auto-processing domain	C-terminal	High	Text match	3502 proteins / 3959 hits
IPR036388	RBD	IPR036388	416	484	Merged direct domain	Winged helix-like DNA-binding domain superfamily	C-terminal	Low	Positional only	96 proteins / 96 hits

Tail Spike Domain Segmentation

This protein has been segmented into three structural domains: N-terminal, central domain, and C-terminal.

Domain Layout

N-terminal

Central

C-terminal

QZI79674.1

1 507

Domain	Start	End	Length (AA)	Confidence
N-terminal	1	50	50	0,9733
Central domain	51	351	302	0,9576
C-terminal	352	507	155	0,9661

Legend: N-terminal Central domain C-terminal

3D Structure with Domain Coloring

The structure is colored according to the domain segmentation: N-terminal (blue), Central (green), C-terminal (pink).

Domain Coloring

N-terminal
1-50

Central
51-351

C-terminal
352-507

Taxonomy

	Name	Taxonomy ID	Lineage
Phage	Escherichia phage vB_EcoP-101118B1 [NCBI]	2865797	Viruses > Duplodnaviria > Heunggongvirae > Uroviricota > Caudoviricetes
Host	Escherichia coli [NCBI]	562	cellular organisms > Bacteria > Pseudomonadati > Pseudomonadota > Gammaproteobacteria > Enterobacterales

Coding sequence (CDS)

Genbank protein accession

QZI79674.1 [NCBI]

Genbank nucleotide accession

MZ234020.1 [NCBI]

CDS location

range 40262 -> 41785
strand +

CDS

ATGGCTAAACTAACGAGAGTCACTGACTGGCTTGTTAAGGTGAAGTCTAGACTCACTGGTGCAGTAGAGCGACTGCTTGAAGATAAGTTAAATGACACGGTTAGTGTTAAGGACTTCGGTGCTAAGGGTGACGGTGTGACAGACGACACACAAGCATTTGCTGCCGCCTCAGCCGCATCGCCTCAAGGTGTTTATGTGCCTGACGGAACATATTTATTACCAGAAGATATTAATGGCAGGTTCTATGGTTCTGGTAAACGCATCAAGGCTGTAGGTGATGGTGGTATTCCTTTTACCAATGTAGCTCAGTCACATAGTAACCTAATATTAGGATATGATGCTGCAAAGGATTACACGGACGAAGGGAAAGGCAACCAATTAGTATTACTTGGCCCAAGCTCCGGTCGTAACCTTACCACTGGTACTAACTCCATTGTGGTAGGTGTTGGTGGCCTATCGGGTGATACATTAGAAGATGCACTAACAGATAAATCACCTTTCACTGGTACAGAGATTATTAGCATTGGTATCAATGCTCTTAAGAAAACTACCACTGGCAACAACATGATTGGTATTGGTCGTGATGCCTTGAACGAGTGTAAAGATGGAAGATTTAACGTAGCTGTAGGTATGTCTGCTTTGCAGCAGCTACACTCTGGTGAGGCTAACGTAGCAATAGGGCGTTCAGCCGGTATGCGTACTGGCATCTTCACTAACGAAGAGGGTGTACGATTAGGCTATACAAAATGTAGCGGTAATACCTTAATAGGTAACGCGGCTGGTCGTGAATTGAAGTCAGGTAATCATAACACCGCCGTAGGCAATGGTGCTATGCGAGGTGTCAGTTCTGATATTAATCCATATACTGGCACTCTAGAGGGTAATTTTAATACAGCTATTGGTGTTGATACATTAAACTCCTTAGCATCTGGTGAGTTGAACACCATGATTGGCGCAAGGGCTGGACGTAAATTACCTAGTGGCTCTGGTAACATCTTCATAGGTGCGGATGCAGGTGCAGGTATTAACGTTGAAAAGTCTAACACTCTCATTATTAACAACCACACTGGCTTACCTTTCGTAGAAGGTATTATGGGTGGTGCTCAGAGTGGGAATAACTACTTACGTGTTGATGGCAGTGTAGCACCTCAGATTGATAACACAAGAACTTGTGGTCAGTCTAGCCGTAGATGGCAGACTGTCTTTGCTACCAATGGTGTTATCCAGACATCGGATGGACGATGCAAGGATGTCTACGATATTGCCAAGAAGGAGTACATGGCTGGTCTAGAGTTAGCCTCTAGTATGATTAAGTTCAAATGGACAGATACTGAAGAAGATAAGTATCACTTCGGTTGTCTGGCACAAGAGGTCATGCTGATTATGGAGAAACATGGGTTAAACCCTCTGGATTATTCCCTCGTTACCTATGATGCTGAAGCAGATATGTATGGTGTTAACTATGCAGAATTGTCTTGCTTCTGTATCGCAGCAATGTCCAATCATGTACTAGGCAGTGCGTAA

Genome Context

Tertiary structure

PDB ID

0e4e7d5718a031efbb82b59a56db7d96f7672279435cd6ee4370fe929b2fb564

ESMFold

Source ESMFold

Method ESMFold

Resolution 0,7763

Oligomeric State monomer

Download PDB

Model Confidence

Very high
pLDDT > 90

High
90 > pLDDT > 70

Low
70 > pLDDT > 50

Very low
pLDDT < 50

Literature

Title	Authors	Date	PMID	Source
Naturally bred epsilon2 phages have an improved host range and effectivity in uropathogenic E. coli over their ancestor phages	Saez,D., Loose,M., Mutti,M., Visram,Z., Hitzenhammer,E., Dippel,D., Tisakova,L., Schertler,S., Wittmann,J., Corsini,L. and Wagenlehner,F.	2020-05-19	—	GenBank

Protein

Domains

Domains [InterPro]

Domains [InterPro]

Tail Spike Domain Segmentation

Tail Spike Domain Segmentation

3D Structure with Domain Coloring

Domain Coloring

Taxonomy

Coding sequence (CDS)

Coding sequence (CDS)

Genome Context

Genome Context

Tertiary structure

Predicted Aligned Error (PAE)

Model Confidence

Literature