Protein

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Genbank accession

CEK40415.1 [GenBank]

Protein name

Putative regulator of chromosome condenstation family protein

RBP type

TSP

Evidence DepoScope

Probability 1,00

Protein sequence

MKKNKLLQRGSLFGNKEFKIEEFNKNFDTFNVKDIFTDMDSGSVFIIKDDLKLYAAGYNVFGNLGLGNKVSPIRYFSKIDIDNVKYVSSSGTHSLLLKNNGDVYSTGLNTDGELGLGDNIDRNTFTKINISNVKQIACGNGYSMLVTNDNELYVCGNNKFGGIGLGNTSTVNTFTKIDNLSVKEIFAGVSCSYILTLNNEVYSTGTNSYGQLGLNDTTNRNIFTKVNLDNVIKISTAQGAVNFLLENGDVYGCGDNSNGQVGVGGGATVTVLTKLSISNVKNIESGRYHKFYIANNNDIYVTGANPDGRLGDKINCDRSTYTPRKSSISIKNISKIKCAHAISFILTSNNELYMTGDNSYSFSYLKRYDKFIYGFEKFEDFDIEECNHIESIDNRLLINKNDERVLDIGLENNFVNISLVKANDTSTFIVVNGNELYAAGYNAYGGLGLGHNRHCYEFTRVPLELEEGVTIKDIYLNLGSYFTFILLSDNTLYSTGYNVFGVLGLGDNINRNTFTKVNISSVDKISVGDNHALLKTTTNELFSTGLNNYGQLGLNDTTNRNIFTKVSTVTYVNEIIAYSNSSYCIDNSRISYAAGYNVFGELSLNDTSSRSVFVKMRYSRYKTDTTVSDVSNIAEIIPFNNGCLIRTTSNNYYVSGRHNYYSTSIKNSVTDDYYSRFGEFVGSKNSNANEVAVLIDEPKLSKVLVSNYNLCLLLDASDGGYKEIKFTGRPSTFGASSQDKNLGLRSLISSSMPYYNHYLGTDNLLYTTSKTRMESKFEIRGRNAGGQRGDSSYYSNSQKYTLSNAFFAYNSQVIYASGLRIVIKDYFGNIYCSGVNSHGCFGIKKPYDVRHDGFVNISKQFSKKYIISNIKEIKSDRQALYILLNNSEGYVCGNNAGNKLGTIKARSEFIKVPIDNIKEFIPSNDCLFILTNNNQVYSIGTNDLGQLGLGDNIDRGTFTKVPIDNVKKVITCYKSSYILTYDNELFSTGSNGYGQLGLGDNINRNTFTKVNISGTIKDIFCGRYVFIILLENDNIISLMGCGNRNYISSNTNSNSLTKINIEGLTDPSTISNLMLEEGKTIITMKNRIFVTGYNSLGGLGVGTSYNNSSGYIEGYKDLAFNSNIKEVALGEYTIFVLLENGDLYSGGNADDGIGFNESGTVVLKKLTSNIKHIYANGKNAYYIDNDNALYVFGSRQLGQINNYSDVVQKTPVRNCLNVKQVYTQHNGLIVQYTNNKLEGKGNAVVGQVGIFNGHEENQIANTSGDNPSDLSFSNEMSIIRNNYGLLVNKKIFLHNDDSINYRIPFGTNAGNYSTSLPFDNIKKMSLSSTHSILILENGDVYGCGSNQFGELAINKSELTTTSEFIKINLTNIIDIACGDNFTYFLKNDGSLFSIGKNSEYQLGIGHNDEVNELQEVLTISNIREIYAYSNYILAITTEGQLYVQGYNINGILGLNENTKNTIIKLFTKVLENVKYIKSYDDKHIFVIKNDKTLYVTGINKETYKIKDVEIGSMLYTFSQIYIPRDVNDIVDALIKDETLYIISKVDSEKTCLEIKNKSYSSIEIDLQNPNNELTKIEMFINNISSSIIEDLSTGTVTFEINPENLVLGENKIVFKAHSDIGNNLYINVYIYKKETGATIVKDSTVLIDGNTYNVSSIVDNSQDVVLTLNKGLLEDLNSNNPIYHLVNKLKVQLKINESDTFKDMVKVETRKTENGYKEIYELKDMNIQSAQPKVIVEEGNTNTTIKKPSMLFNLDVETL

Physico‐chemical properties

protein length:	1759 AA
molecular weight:	195674,25020 Da
isoelectric point:	5,77089
aromaticity:	0,10290
hydropathy:	-0,30080

Domains

Domains [InterPro]

IPR009091
STR
14–181

IPR009091 IPR009091 IPR009091 DC_1898 IPR009091 IPR009091 IPR009091 DC_1828

IPR009091
STR
45–361

IPR009091 IPR009091 IPR009091 IPR009091 IPR009091

IPR000408
STR
51–100

IPR000408 IPR000408 IPR000408 IPR000408 IPR000408 IPR000408 IPR000408 PF13540 IPR000408 PF13540 PF13540

IPR000408
STR
101–149

IPR000408 IPR000408 IPR000408 IPR000408

IPR051553
Unmapped
129–360

IPR051553

CEK40415.1

1 1759

Architecture

STR

RBD

STR 14-367 | STR 387-1282 | STR 1295-1520 | RBD 1521-1759

Legend: ATT STR RBD CBM LEC ENZ CHP LNK TAS TTP UNK Unmapped

Domains [InterPro]

Domain ID	Category	Cluster	Start	End	Layer	Name	Pref Zone	Confidence	Evidence	Support
IPR009091	STR	IPR009091	14	181	Merged direct domain	Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II	Central	Low	Positional only	141 proteins / 141 hits
IPR009091	STR	IPR009091	45	361	Merged direct domain	Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II	Central	Low	Positional only	141 proteins / 141 hits
IPR000408	STR	DC_0062	51	100	InterPro cluster	Regulator of chromosome condensation, RCC1	Central	Low	Positional only	52 proteins / 98 hits
IPR000408	STR	DC_0062	100	146	InterPro cluster	Regulator of chromosome condensation, RCC1	Central	Low	Positional only	52 proteins / 98 hits
IPR000408	STR	DC_0062	101	149	InterPro cluster	Regulator of chromosome condensation, RCC1	Central	Low	Positional only	52 proteins / 98 hits
IPR051553	Unmapped	-	129	360	InterPro	Ran GTPase-activating	-	-	-	-
IPR000408	STR	DC_0062	151	167	InterPro cluster	Regulator of chromosome condensation, RCC1	Central	Low	Positional only	52 proteins / 98 hits
IPR009091	STR	IPR009091	182	367	Merged direct domain	Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II	Central	Low	Positional only	141 proteins / 141 hits
IPR000408	STR	DC_0062	201	217	InterPro cluster	Regulator of chromosome condensation, RCC1	Central	Low	Positional only	52 proteins / 98 hits
IPR000408	STR	DC_0062	248	296	InterPro cluster	Regulator of chromosome condensation, RCC1	Central	Low	Positional only	52 proteins / 98 hits
IPR000408	STR	DC_0062	283	299	InterPro cluster	Regulator of chromosome condensation, RCC1	Central	Low	Positional only	52 proteins / 98 hits
IPR000408	STR	DC_0062	299	313	InterPro cluster	Regulator of chromosome condensation, RCC1	Central	Low	Positional only	52 proteins / 98 hits
IPR009091	STR	IPR009091	387	721	Merged direct domain	Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II	Central	Low	Positional only	141 proteins / 141 hits
IPR009091	STR	IPR009091	412	674	Merged direct domain	Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II	Central	Low	Positional only	141 proteins / 141 hits
IPR000408	STR	DC_0062	485	506	InterPro cluster	Regulator of chromosome condensation, RCC1	Central	Low	Positional only	52 proteins / 98 hits
PF13540	STR	DC_0403	522	551	InterPro cluster	Regulator of chromosome condensation (RCC1) repeat	Central	Low	Positional only	6 proteins / 8 hits
DC_1898	STR	DC_1898	722	778	Novel HMM	DC_1898	Central	Low	Positional only	3 proteins / 3 hits
IPR009091	STR	IPR009091	779	1065	Merged direct domain	Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II	Central	Low	Positional only	141 proteins / 141 hits
IPR009091	STR	IPR009091	854	1079	Merged direct domain	Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II	Central	Low	Positional only	141 proteins / 141 hits
IPR000408	STR	DC_0062	982	1024	InterPro cluster	Regulator of chromosome condensation, RCC1	Central	Low	Positional only	52 proteins / 98 hits
IPR000408	STR	DC_0062	983	1032	InterPro cluster	Regulator of chromosome condensation, RCC1	Central	Low	Positional only	52 proteins / 98 hits
IPR009091	STR	IPR009091	1080	1282	Merged direct domain	Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II	Central	Low	Positional only	141 proteins / 141 hits
IPR009091	STR	IPR009091	1081	1254	Merged direct domain	Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II	Central	Low	Positional only	141 proteins / 141 hits
IPR009091	STR	IPR009091	1295	1520	Merged direct domain	Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II	Central	Low	Positional only	141 proteins / 141 hits
IPR009091	STR	IPR009091	1316	1500	Merged direct domain	Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II	Central	Low	Positional only	141 proteins / 141 hits
PF13540	STR	DC_0403	1321	1349	InterPro cluster	Regulator of chromosome condensation (RCC1) repeat	Central	Low	Positional only	6 proteins / 8 hits
IPR000408	STR	DC_0062	1338	1388	InterPro cluster	Regulator of chromosome condensation, RCC1	Central	Low	Positional only	52 proteins / 98 hits
PF13540	STR	DC_0403	1372	1401	InterPro cluster	Regulator of chromosome condensation (RCC1) repeat	Central	Low	Positional only	6 proteins / 8 hits
DC_1828	RBD	DC_1828	1521	1759	Novel HMM	DC_1828	C-terminal	Low	Positional only	4 proteins / 4 hits

Tail Spike Domain Segmentation

This protein has been segmented into three structural domains: N-terminal, central domain, and C-terminal.

Domain Layout

N-terminal

Central

C-terminal

CEK40415.1

1 1759

Domain	Start	End	Length (AA)	Confidence
N-terminal	1	29	29	0,6031
Central domain	30	228	200	0,5750
C-terminal	229	1759	1530	0,4041

Note: Constraints were applied during segmentation.
Fixed 23 C-terminal predictions appearing before Central domain

Legend: N-terminal Central domain C-terminal

3D Structure with Domain Coloring

The structure is colored according to the domain segmentation: N-terminal (blue), Central (green), C-terminal (pink).

Domain Coloring

N-terminal
1-29

Central
30-228

C-terminal
229-1759

Taxonomy

	Name	Taxonomy ID	Lineage
Phage	Clostridium phage phiCD211 [NCBI]	1582152	Viruses > Duplodnaviria > Heunggongvirae > Uroviricota > Caudoviricetes
Host	No host information

Coding sequence (CDS)

Genbank protein accession

CEK40415.1 [NCBI]

Genbank nucleotide accession

LN681537 [NCBI]

CDS location

range 43298 -> 48577
strand +

CDS

ATGAAAAAGAATAAACTATTACAAAGAGGTTCTTTATTTGGAAACAAAGAATTTAAAATAGAAGAGTTTAATAAAAATTTTGATACTTTTAATGTTAAAGATATATTTACAGATATGGATTCTGGTTCTGTGTTTATAATTAAGGATGATTTAAAGTTATATGCAGCAGGATATAATGTTTTTGGCAATTTAGGACTTGGAAATAAAGTATCACCTATAAGATATTTTTCAAAAATAGATATTGACAATGTTAAGTATGTTTCATCTTCTGGAACTCATTCTCTTTTACTTAAAAATAACGGAGATGTGTATTCTACTGGCTTAAACACAGATGGGGAGTTAGGTTTGGGAGATAATATTGATAGAAATACTTTTACTAAGATAAATATAAGTAATGTAAAACAAATTGCTTGTGGGAATGGCTATTCTATGTTAGTTACAAATGACAACGAGCTTTATGTATGTGGTAATAATAAATTTGGAGGGATAGGCTTAGGAAATACATCTACTGTAAATACATTTACTAAAATTGATAATTTGAGTGTTAAAGAAATATTTGCAGGAGTCAGTTGTTCATATATATTAACTTTAAATAATGAAGTCTATTCAACAGGTACAAATTCCTATGGGCAGTTAGGACTTAATGACACTACTAATAGAAATATTTTTACTAAAGTAAATTTAGATAATGTAATAAAGATTTCTACTGCTCAAGGTGCTGTAAATTTTCTTTTAGAAAATGGGGATGTCTATGGTTGTGGAGATAATTCAAATGGGCAAGTTGGTGTTGGTGGAGGAGCTACAGTAACAGTCTTAACAAAACTATCTATATCTAATGTAAAAAATATAGAAAGTGGTAGATATCATAAATTTTATATAGCTAATAATAATGATATATATGTAACTGGAGCCAACCCAGATGGGCGTTTAGGAGATAAAATAAATTGTGATAGATCAACATATACTCCTAGAAAATCTTCTATTAGTATTAAAAATATAAGTAAAATTAAATGTGCTCATGCTATAAGCTTTATATTAACTAGCAACAATGAATTGTATATGACAGGAGATAACAGTTATAGTTTTTCTTATTTAAAAAGATATGATAAATTTATATATGGATTTGAAAAATTTGAGGACTTTGATATTGAAGAATGTAATCATATTGAGTCTATTGATAATAGATTATTAATAAATAAAAATGATGAAAGAGTTTTAGATATAGGGCTTGAAAATAATTTTGTGAATATCTCTTTAGTGAAAGCAAATGACACCTCTACATTTATTGTTGTGAATGGTAATGAACTATACGCAGCAGGATACAACGCTTATGGAGGTTTAGGTTTAGGTCATAATCGTCATTGTTATGAGTTTACTAGAGTGCCATTGGAATTAGAAGAAGGAGTTACTATAAAAGATATATATTTAAATCTAGGCTCATATTTCACGTTTATATTACTAAGTGATAATACATTATATTCAACAGGATATAATGTATTTGGAGTGTTAGGATTAGGGGATAATATTAATAGAAATACTTTTACTAAAGTAAATATTTCTTCTGTTGACAAAATTTCTGTAGGAGATAACCATGCGTTATTAAAAACAACTACTAATGAATTATTTTCAACTGGTTTAAACAATTATGGGCAGTTAGGACTTAATGACACTACTAATAGAAATATTTTTACTAAAGTAAGTACTGTAACTTATGTAAATGAAATTATTGCATATTCAAATTCTTCATATTGCATAGACAATAGCAGAATATCTTATGCAGCAGGATATAATGTTTTTGGCGAATTAAGTCTTAATGATACCTCAAGTAGGAGCGTTTTTGTTAAGATGAGATATTCAAGATATAAAACAGATACAACAGTATCAGATGTATCTAACATTGCTGAAATTATTCCTTTTAATAATGGATGTTTAATTAGAACTACGTCTAATAACTACTATGTTTCTGGGAGACATAATTATTATAGCACAAGTATTAAAAATTCTGTAACTGATGATTATTATTCAAGGTTTGGAGAGTTTGTAGGAAGTAAAAACTCAAATGCAAATGAAGTCGCAGTTTTAATAGATGAACCTAAATTATCAAAAGTTCTGGTTTCTAACTATAATTTATGTTTATTATTAGATGCTAGTGATGGAGGATATAAAGAAATAAAATTCACAGGAAGACCTTCGACTTTTGGAGCTTCATCCCAAGACAAGAATTTAGGTTTAAGAAGTCTTATATCGTCTTCTATGCCTTATTATAATCATTATCTTGGAACAGACAATCTTTTATATACAACAAGTAAAACAAGGATGGAGTCTAAATTTGAAATAAGAGGTAGAAATGCAGGTGGGCAAAGAGGAGACAGTAGTTATTATTCTAATAGTCAAAAATACACATTATCAAATGCTTTTTTTGCATATAATTCACAAGTAATATATGCTAGTGGATTAAGGATAGTAATTAAAGATTATTTTGGGAACATATATTGTTCTGGAGTAAATTCTCATGGCTGTTTTGGCATAAAAAAACCTTATGATGTTAGACATGATGGTTTTGTAAATATATCAAAACAATTTTCTAAAAAATATATCATATCAAATATAAAAGAAATTAAAAGTGATAGACAAGCTTTATATATATTATTAAATAATAGCGAAGGATATGTCTGTGGTAATAATGCTGGTAACAAGTTAGGGACAATTAAAGCTCGGTCTGAATTTATAAAAGTTCCTATAGATAATATAAAAGAATTTATTCCATCGAATGATTGTTTATTTATTCTTACAAATAATAATCAAGTCTATTCAATTGGAACAAATGACTTAGGGCAATTAGGTTTAGGAGATAATATTGATAGGGGTACTTTTACTAAGGTGCCTATTGATAATGTAAAAAAAGTAATAACATGTTACAAATCTTCTTACATTCTAACCTATGACAATGAATTATTTTCAACTGGTTCAAATGGCTATGGTCAATTAGGATTAGGGGATAATATTAATAGAAATACTTTTACTAAAGTAAATATTTCTGGAACAATAAAGGATATATTTTGTGGAAGGTATGTTTTTATTATATTATTGGAGAATGATAATATAATTTCTTTAATGGGTTGTGGAAATAGAAATTACATAAGTTCAAATACAAATTCAAACAGTTTAACTAAAATAAATATTGAAGGATTAACAGACCCATCAACTATATCAAATTTAATGTTGGAAGAAGGCAAAACTATAATTACAATGAAAAATAGAATATTTGTCACAGGATATAACTCATTAGGAGGTTTAGGTGTTGGTACTTCATATAATAATTCATCAGGATATATTGAAGGATATAAGGATTTAGCGTTTAATAGTAATATAAAAGAGGTTGCTCTAGGAGAATACACTATTTTTGTTTTACTTGAAAATGGAGATTTATATTCTGGAGGAAATGCTGATGATGGTATAGGTTTTAATGAATCTGGTACTGTAGTATTAAAAAAATTAACAAGTAATATAAAGCACATATATGCAAATGGTAAAAATGCTTATTATATAGATAATGATAATGCCTTATATGTGTTTGGTAGTAGACAATTGGGTCAAATCAATAATTATTCTGATGTTGTACAAAAAACACCTGTTAGAAATTGCCTTAATGTAAAACAGGTATATACACAGCATAATGGTCTTATAGTTCAATATACTAATAATAAATTAGAAGGAAAAGGTAATGCTGTAGTTGGTCAAGTAGGTATTTTTAATGGACATGAAGAAAATCAGATTGCAAACACTTCTGGTGATAATCCTAGTGATTTAAGTTTTTCTAATGAAATGTCTATTATAAGAAATAATTATGGACTATTAGTAAATAAGAAGATATTTTTACATAATGATGATAGTATTAATTATAGAATACCATTTGGCACAAATGCTGGAAATTACTCAACTTCATTGCCTTTTGATAATATAAAAAAGATGTCTTTATCATCAACTCATTCAATTTTGATATTAGAAAATGGGGATGTCTATGGTTGTGGTTCAAATCAATTTGGGGAACTTGCTATAAATAAATCTGAGCTAACAACAACTTCTGAATTTATAAAAATTAACTTAACAAATATAATAGATATTGCTTGTGGTGATAATTTTACTTACTTCTTAAAAAATGATGGCTCATTGTTTTCTATTGGTAAAAACTCAGAATATCAACTTGGAATAGGGCATAATGATGAGGTTAATGAGTTACAAGAAGTATTAACTATTTCTAATATAAGGGAGATATATGCTTATAGTAATTATATATTGGCTATAACTACAGAAGGTCAATTATACGTACAAGGATATAATATAAATGGGATTTTAGGACTGAATGAGAATACAAAAAATACAATTATTAAATTATTTACTAAAGTATTAGAAAATGTAAAATATATAAAATCTTATGATGATAAACATATATTTGTTATAAAAAATGATAAGACTTTGTATGTTACAGGGATAAATAAGGAAACATATAAAATTAAAGATGTAGAGATTGGTTCTATGTTATATACTTTCTCACAAATATATATTCCAAGAGATGTTAATGATATAGTGGATGCTTTAATAAAAGATGAAACATTATATATAATCTCAAAAGTAGATTCAGAGAAAACTTGTTTGGAAATAAAGAATAAGTCATACTCATCTATTGAAATAGATTTGCAAAATCCAAATAATGAATTGACAAAAATAGAGATGTTTATAAATAATATTAGTTCAAGTATAATAGAAGACTTATCTACAGGAACAGTCACGTTTGAGATTAATCCAGAGAATTTAGTTCTTGGAGAAAATAAGATTGTATTTAAAGCACATTCTGACATTGGAAATAATTTATATATAAATGTTTATATTTATAAAAAAGAAACAGGAGCAACTATAGTAAAAGATTCAACTGTATTAATCGATGGGAATACTTATAATGTATCTAGTATAGTTGATAATTCACAAGATGTAGTACTTACACTCAATAAAGGTCTGTTAGAAGATTTAAATTCTAACAATCCAATTTATCATTTAGTAAATAAATTAAAAGTACAATTAAAGATAAATGAATCAGATACATTTAAAGATATGGTTAAAGTAGAGACAAGAAAAACTGAGAATGGATATAAGGAGATATATGAGTTAAAAGATATGAATATACAATCTGCACAACCTAAAGTAATAGTAGAAGAAGGAAACACTAATACAACTATAAAAAAACCATCTATGTTATTCAATTTAGATGTTGAAACACTTTAA

Genome Context

Tertiary structure

PDB ID

5b50c9ffb71d5adc8a8ea2630098ba536932f1d9f257ea7a89326c83467ac617

ColabFold

Source ColabFold

Method ColabFold

Resolution 0,6554

Oligomeric State monomer

Download PDB

Model Confidence

Very high
pLDDT > 90

High
90 > pLDDT > 70

Low
70 > pLDDT > 50

Very low
pLDDT < 50

Literature

Title	Authors	Date	PMID	Source
High prevalence and genetic diversity of large phiCD211-like prophages in Clostridium difficile	Garneau,J.R., Sekulovic,O., Dupuy,B., Soutourina,O., Monot,M. and Fortier,L.C.	2018-02	—	GenBank

Protein

Domains

Domains [InterPro]

Domains [InterPro]

Tail Spike Domain Segmentation

Tail Spike Domain Segmentation

3D Structure with Domain Coloring

Domain Coloring

Taxonomy

Coding sequence (CDS)

Coding sequence (CDS)

Genome Context

Genome Context

Tertiary structure

Predicted Aligned Error (PAE)

Model Confidence

Literature