Protein

View in Explore
Genbank accession
QBX29146.1 [GenBank]
Protein name
hyaluronate lyase
RBP type
TSP
Evidence DepoScope
Probability 1,00
TSP
Evidence RBPdetect2
Probability 0,96
Protein sequence
MSENIPLRVQFKRMKAAEWARSDVILLESEIGFETDTGFARAGDGHNRFSDLGYISPLDYNLLTNKPNIDGLATKVETAQKLQQKADKETVYTKAESKQELDKKLNLKGGVMTGQLKFKPAATVAYSSSTGGAVNIDLSSTRGAGVVVYSDNDTSDGPLMSLRTGKETFNQSALFVDYKGTTNAVNIAMRQPTTPNFSSALNITSGNENGSAMQLRGSEKALGTLKITHENPSIGADYDKNAAALSIDIVKKTNGAGTAAQGIYINSTSGTTGKLLRIRNLSDDKFYVKSDGGFYAKETSQIDGNLKLKDPTANDHAATKAYVDKAISELKKLILKK
Physico‐chemical
properties
protein length:337 AA
molecular weight: 36283,39200 Da
isoelectric point:9,10753
aromaticity:0,06528
hydropathy:-0,48487

Domains

Domains [InterPro]
SSF69349
STR
7–335
SSF69349
IPR041352
ATT
9–45
IPR041352 IPR009860
QBX29146.1
1 337
Architecture
ATT
STR
ATT 7-45 | STR 46-335 |
Legend: ATT STR RBD CBM LEC ENZ CHP LNK TAS TTP UNK Unmapped

Tail Spike Domain Segmentation

Tail Spike Domain Segmentation

This protein has been segmented into three structural domains: N-terminal, central domain, and C-terminal.

Domain Layout
N-terminal
Central
C-terminal
QBX29146.1
1 337
Domain Start End Length (AA) Confidence
N-terminal 1 112 112 0,9888
Central domain 113 311 200 0,1863
C-terminal 312 337 25 0,9888
Legend: N-terminal Central domain C-terminal
3D Structure with Domain Coloring

The structure is colored according to the domain segmentation: N-terminal (blue), Central (green), C-terminal (pink).

Domain Coloring
N-terminal
1-112
Central
113-311
C-terminal
312-337

Taxonomy

  Name Taxonomy ID Lineage
Phage Streptococcus phage Javan484
[NCBI] 		2548199 Viruses > Duplodnaviria > Heunggongvirae > Uroviricota > Caudoviricetes
Host Streptococcus pyogenes HSC5
[NCBI] 		1336746 Bacillota > Bacilli > Lactobacillales > Streptococcaceae > Streptococcus > Streptococcus pyogenes

Coding sequence (CDS)

Coding sequence (CDS)
Genbank protein accession
QBX29146.1 [NCBI]
Genbank nucleotide accession
MK448957 [NCBI]
CDS location
range 37046 -> 38059
strand +
CDS
ATGAGTGAAAATATACCGCTGCGAGTCCAATTTAAGCGCATGAAAGCCGCCGAGTGGGCTCGTAGTGATGTCATCTTACTGGAGAGCGAGATAGGCTTTGAGACAGACACAGGTTTTGCCAGAGCAGGTGATGGGCACAATCGATTTAGTGACCTTGGATACATTAGTCCACTCGATTACAATCTACTGACTAACAAGCCAAATATTGATGGATTAGCGACAAAAGTCGAGACCGCTCAGAAACTACAACAAAAAGCAGATAAAGAGACCGTCTATACAAAAGCTGAATCGAAGCAAGAGCTTGACAAGAAATTAAATCTCAAAGGTGGCGTTATGACAGGTCAACTAAAATTTAAGCCAGCCGCCACTGTTGCTTATTCCTCGTCAACGGGTGGAGCGGTCAATATTGACTTGTCGTCTACCAGAGGTGCTGGTGTTGTTGTCTATTCTGACAATGATACCAGTGATGGGCCGTTAATGAGCTTGCGGACGGGTAAAGAGACCTTTAATCAATCGGCGCTTTTTGTCGACTATAAGGGGACAACAAATGCCGTTAATATTGCGATGCGTCAGCCAACCACCCCCAATTTTTCATCGGCGCTTAATATTACTAGCGGCAATGAAAATGGTAGTGCAATGCAGCTACGAGGGTCAGAAAAAGCGCTAGGAACGCTAAAAATTACTCATGAGAACCCAAGTATTGGAGCGGATTATGATAAAAATGCGGCAGCGTTATCCATTGATATTGTCAAAAAGACAAACGGTGCAGGAACAGCCGCTCAGGGAATCTACATTAACTCAACCTCAGGCACGACAGGGAAGTTGCTTAGGATTAGAAACCTTAGTGATGATAAGTTCTACGTCAAGTCTGACGGTGGTTTTTATGCCAAGGAAACTTCGCAGATTGATGGCAACCTGAAACTCAAGGACCCCACAGCGAATGATCATGCGGCAACCAAAGCTTATGTAGATAAAGCAATTTCTGAGTTAAAAAAACTCATACTAAAAAAATAG

Genome Context

Genome Context

Tertiary structure

PDB ID
83342f70d424df2731f1191112ebd8d1fbfed9e9ff29a370e820d7b99ea93e7e
ESMFold
Source ESMFold
Method ESMFold
Resolution 0,7844
Oligomeric State monomer
Download PDB
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50

Literature

Title Authors Date PMID Source
Prophages and satellite prophages are widespread among Streptococcus species and may play a role in pneumococcal pathogenesis Rezaei Javan,R., Ramos-Sevillano,E., Akter,A., Brown,J. and Brueggemann,A.B. 2018-12-20 — GenBank