Protein

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Genbank accession
QBX28292.1 [GenBank]
Protein name
hyaluronate lyase
RBP type
TSP
Evidence DepoScope
Probability 1,00
TSP
Evidence RBPdetect2
Probability 0,96
Protein sequence
MTETIPLRVQFKRMKAAEWASSDVVLLEGEIGFETDTGFAKFGDGQNTFSKLKYLTGPKGPKGDTGIQGKTGGTGPRGPAGKPGTTDYDQLQNKPDLGAFAQKEETNSKITKLESSKADKSAVYSKAESKIELDKKLSLTGGIVTGQLQFKPNKSGIKPSSSVGGAINIDMSKSEGAAMVMYTNKDTTDGPLMILRSDKDTFDQSAQFVDYSGKTNAVNIVMRQPSAPNFSSALNITSANEGGSAMQIRGVEKALGTLKITHENPNVEAKYDENAAALSIDIVKKQKGGKGTAAQGIYINSTSGTAGKMLRIRNKNEDKFYVGPDGGFHSGANSTVAGNLTVNYPTSEKHAATKKYVDEKIAELKKLILKK
Physico‐chemical
properties
protein length:371 AA
molecular weight: 39538,18920 Da
isoelectric point:9,35593
aromaticity:0,06199
hydropathy:-0,58598

Domains

Domains [InterPro]
SSF69349
STR
7–369
SSF69349
IPR041352
ATT
9–46
IPR041352 G3DSA:1.20.5.320 IPR009860
QBX28292.1
1 371
Architecture
ATT
STR
ATT 7-46 | STR 47-369 |
Legend: ATT STR RBD CBM LEC ENZ CHP LNK TAS TTP UNK Unmapped

Tail Spike Domain Segmentation

Tail Spike Domain Segmentation

This protein has been segmented into three structural domains: N-terminal, central domain, and C-terminal.

Domain Layout
N-terminal
Central
C-terminal
QBX28292.1
1 371
Domain Start End Length (AA) Confidence
N-terminal 1 143 143 0,9482
Central domain 144 342 200 0,1112
C-terminal 343 371 28 0,9843
Legend: N-terminal Central domain C-terminal
3D Structure with Domain Coloring

The structure is colored according to the domain segmentation: N-terminal (blue), Central (green), C-terminal (pink).

Domain Coloring
N-terminal
1-143
Central
144-342
C-terminal
343-371

Taxonomy

  Name Taxonomy ID Lineage
Phage Streptococcus phage Javan448
[NCBI] 		2548174 Viruses > Duplodnaviria > Heunggongvirae > Uroviricota > Caudoviricetes
Host Streptococcus pyogenes Alab49
[NCBI] 		487215 Bacillota > Bacilli > Lactobacillales > Streptococcaceae > Streptococcus > Streptococcus pyogenes

Coding sequence (CDS)

Coding sequence (CDS)
Genbank protein accession
QBX28292.1 [NCBI]
Genbank nucleotide accession
MK448942 [NCBI]
CDS location
range 18033 -> 19148
strand +
CDS
ATGACAGAAACTATACCATTAAGAGTCCAATTTAAGCGGATGAAAGCCGCCGAGTGGGCAAGTAGTGATGTCGTCTTACTGGAGGGTGAGATTGGCTTTGAGACTGACACTGGTTTTGCTAAGTTTGGCGATGGTCAAAACACTTTTAGTAAGCTTAAGTACCTTACTGGTCCCAAAGGTCCTAAAGGAGACACTGGTATCCAAGGTAAAACTGGAGGAACTGGTCCTCGGGGCCCTGCTGGCAAGCCTGGAACGACAGATTATGATCAACTCCAAAATAAACCAGATCTAGGTGCGTTTGCACAAAAAGAAGAAACTAATAGTAAAATCACCAAATTAGAATCAAGCAAAGCAGATAAAAGCGCTGTTTACTCAAAAGCAGAGTCAAAAATAGAGCTAGACAAAAAATTGAGCTTAACAGGCGGCATAGTGACAGGACAACTACAGTTTAAACCTAATAAAAGTGGTATTAAACCCTCATCTTCCGTAGGAGGAGCGATTAACATTGATATGTCTAAATCGGAAGGTGCTGCTATGGTGATGTATACAAATAAAGATACTACTGATGGACCATTGATGATTTTACGTTCTGACAAAGATACGTTTGATCAGTCAGCTCAATTTGTGGATTACAGCGGTAAGACTAATGCTGTAAATATTGTAATGCGCCAGCCAAGCGCACCTAATTTTTCCTCGGCACTTAATATAACCAGTGCCAACGAAGGCGGTAGTGCGATGCAAATTAGAGGCGTCGAAAAAGCGCTAGGAACGCTCAAAATCACACACGAAAACCCAAACGTTGAGGCAAAATACGATGAAAACGCTGCAGCGTTATCTATTGATATCGTTAAAAAACAGAAAGGCGGAAAAGGTACTGCTGCTCAAGGAATCTACATTAACTCAACATCAGGCACAGCTGGTAAAATGCTCAGAATCAGAAATAAAAATGAAGACAAATTTTATGTAGGTCCAGATGGCGGCTTTCACTCAGGTGCAAATTCAACTGTAGCTGGTAATCTAACAGTTAACTATCCAACATCTGAAAAACATGCTGCGACTAAAAAATACGTAGATGAAAAAATTGCTGAGTTAAAAAAACTCATACTAAAAAAATAG

Genome Context

Genome Context

Tertiary structure

PDB ID
0fc658ee9a54edf8b31ba8abbdda969163f02cbfce9fd054ea8af29770198304
ESMFold
Source ESMFold
Method ESMFold
Resolution 0,7586
Oligomeric State monomer
Download PDB
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50

Literature

Title Authors Date PMID Source
Prophages and satellite prophages are widespread among Streptococcus species and may play a role in pneumococcal pathogenesis Rezaei Javan,R., Ramos-Sevillano,E., Akter,A., Brown,J. and Brueggemann,A.B. 2018-12-20 — GenBank